Biotrexate

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  • Contains / Salt: Methotrexate (15 mg)
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Biotrexate Information



Biotrexate Benefits & Uses

Biotrexate is used to treat the following -

Other Benefits

Biotrexate Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 15 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 15 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 12 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 12 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Infant (1 month to 2 years)
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 6 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult(Female)
  • Disease: Breast Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 60 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor


Biotrexate Side Effects

Based on research, the following side effects have been observed when Biotrexate is used -

Moderate

  • Stomatitis (Inflammation of the mouth)

Mild

Common

  • पेट दर्द

Biotrexate Related Warnings

  • Is the use of Biotrexate safe for pregnant women?


    Biotrexate can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

    Severe
  • Is the use of Biotrexate safe during breastfeeding?


    Women who are breastfeeding may experience severe harmful effects after taking Biotrexate . It should only be taken after medical advice.

    Severe
  • What is the effect of Biotrexate on the Kidneys?


    There can be some harmful effects on your kidneys after taking Biotrexate . If you witness any side effects, discontinue its use. Consult your medical practitioner, do as he/she suggests.

    Moderate
  • What is the effect of Biotrexate on the Liver?


    There may be an adverse effect on the liver after taking Biotrexate . If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.

    Moderate
  • What is the effect of Biotrexate on the Heart?


    Biotrexate may have mild side effects on the heart. Most people will never see any effect on the heart.

    Mild


Severe Interaction of Biotrexate with Other Drugs

Biotrexate should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Biotrexate Contraindications

If you are suffering from any of the following diseases, you should not take Biotrexate unless your doctor advises you to do so -



Frequently asked Questions about Biotrexate

  • Is this Biotrexate habit forming or addictive?


    Biotrexate does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can operate a vehicle or heavy machinery after taking Biotrexate since it does not cause drowsiness.

    Safe
  • Is it safe?


    Yes, Biotrexate is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Biotrexate in mental disorders is not effective.

    No

Biotrexate Interactions with Food and Alcohol

  • Interaction between Food and Biotrexate


    There is no information on the effects of taking Biotrexate with food, because this topic has not been scientifically researched yet.

    Unknown
  • Interaction between Alcohol and Biotrexate


    Drinking alcohol while taking Biotrexate may lead to slight side effects. If you experience any side effects, contact your doctor.

    Mild


Frequently asked Questions about Biotrexate

Question over 4 years ago

Can Biotrexate cause hair loss?

Dr. Suhas Bhargav MBBS , General Physician

Yes, Biotrexate causes hair loss (alopecia). It is a known side effect of this drug. This side effect is reversible in nature and it is resolved after the discontinuation of this drug.

Question almost 5 years ago

Is Biotrexate safe to use?

Aakash Shah MBBS, MBBS , General Physician

Yes, Biotrexate is safe to use, if taken in prescribed amount and duration as advised by the doctor. However, certain side effects have been associated with this drug such as gingivitis (inflammation of gum), mouth ulcers, and diarrhoea. If you experience above-mentioned side effects after taking this medicine then inform your doctor and follow his/her instructions.

Question over 4 years ago

Can Biotrexate cure psoriasis?

Dr. Sameer Awadhiya MBBS , Pediatrics

Biotrexate can help in curing psoriasis which is caused by the overactive immune system. It is used in the treatment of severe cases of psoriasis when another treatment with other medications is not working. Biotrexate contains methotrexate that suppresses the body's overactive immune system. This helps in reducing the severity of psoriasis so that patient can use milder therapy for relief. 

Question about 5 years ago

What is Biotrexate ?

Dr. R.K Singh MBBS , Diabetology

Biotrexate is a brand name of methotrexate and it comes in the form of tablet and injection. It is a chemotherapy drug that belongs to the class of drug known as antimetabolites and it also has immunosuppressant properties. It is a prescription drug which is used for the treatment of various types of cancers such as breast cancer, bone cancer, head, and neck cancer. It is also used in the treatment of autoimmune and inflammatory diseases such as psoriasis, rheumatoid arthritis, and Crohn's disease.

Question over 4 years ago

Can Biotrexate raise blood pressure?

Dr. Gaurav MBBS , General Physician

No, Biotrexate does not raise blood pressure (hypertension). It has not been reported by the patients who are taking this drug.



See all substitutes for Biotrexate


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Methotrexate

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 862-863

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 832-834



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