Cozapine

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  • Contains / Salt: Clozapine (25 mg)
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Cozapine Information

Cozapine is a prescription drug, available for use as Tablet. It is typically used for the treatment of Schizophrenia. Secondary and off-label uses of Cozapine have also been mentioned below.

The optimal dosage of Cozapine is largely dependent on the individual's body weight, medical history, gender and age. Individual symptoms and route of administration also determines the right dosage. Refer to the dosage section for a detailed discussion.

The side effects typically associated with Cozapine include Blurred vision. While these are the most often observed Cozapine side effects, there are can be others also. These have been listed below. Normally, these side effects of Cozapine are not long lasting and go away when the treatment is finished. However, if these continue for a longer time, consult your doctor right away.

It is also important to note that Cozapine has a Mild effect for pregnant women and Severe effect on lactating mothers. Further, the section on Cozapine related warnings talks about Cozapine's effects on the liver, heart and kidney.

Individuals suffering from medical conditions like Tardive Dyskinesia, Depression, Parkinson's Disease must refrain from the use of Cozapine since this can cause severe adverse effects. The section on Cozapine contraindications lists all such conditions.

Additionally, Cozapine may also adversely react with other medicines. See below for a complete list.

Along with the above-mentioned precautions, remember that taking Cozapine is considered not safe while driving, and is not addictive.



Cozapine Benefits & Uses

Cozapine is used to treat the following -

Main Benefits

Other Benefits

Cozapine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Schizophrenia
  • Before or After Meal: After Meal
  • Single Maximum Dose: 12.5 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: gradually increase 25 - 50 mg/day over a period of 2 week up to target dose of 300 - 450 mg/day
Geriatric
  • Disease: Schizophrenia
  • Before or After Meal: After Meal
  • Single Maximum Dose: 12.5 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: gradually increase 25 - 50 mg/day over a period of 2 week up to target dose of 300 - 450 mg/day


Cozapine Side Effects

Based on research, the following side effects have been observed when Cozapine is used -

Moderate

Mild

Common

  • Blurred vision

Cozapine Related Warnings

  • Is the use of Cozapine safe for pregnant women?


    Cozapine has mild to no side effects in pregnant women.

    Mild
  • Is the use of Cozapine safe during breastfeeding?


    Taking Cozapine may lead to serious side effects if you are breastfeeding. Cozapine should not be taken by breastfeeding women unless prescribed by the doctor.

    Severe
  • What is the effect of Cozapine on the Kidneys?


    Cozapine has very mild side effects on the kidneys.

    Mild
  • What is the effect of Cozapine on the Liver?


    Cozapine may have mild side effects on the liver. Most people will never see any effect on the liver.

    Mild
  • What is the effect of Cozapine on the Heart?


    Cozapine can have moderate side effects on the heart. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate


Severe Interaction of Cozapine with Other Drugs

Cozapine should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate

AcarboseChlorpheniramine,Dextromethorphan,Paracetamol,Phenylephrine
    Paracetamol,Tramadol


      Cozapine Contraindications

      If you are suffering from any of the following diseases, you should not take Cozapine unless your doctor advises you to do so -



      Frequently asked Questions about Cozapine

      • Is this Cozapine habit forming or addictive?


        Forming a habit of Cozapine has not been reported.

        No
      • Is it safe to drive or operate heavy machinery when consuming?


        You may feel sleepy or tired after taking Cozapine. So it is best to avoid driving.

        Dangerous
      • Is it safe?


        Cozapine should be used only after doctor's advice.

        Safe, but take only on Doctor's advise
      • Is it able to treat mental disorders?


        Yes, Cozapine is useful in treating mental disorders.

        Yes

      Cozapine Interactions with Food and Alcohol

      • Interaction between Food and Cozapine


        Eating certain foods may increase the time it takes Cozapine to have an effect. You should consult your doctor about it.

        Mild
      • Interaction between Alcohol and Cozapine


        Taking Cozapine with alcohol can have severely harmful effects on your health.

        Severe


      See all substitutes for Cozapine


      This medicine data has been created by -

      Vikas Chauhan

      B.Pharma, Pharmacy
      5 Years of Experience


      References

      US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Clozaril® (clozapine)

      KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 175,471

      April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 56-58

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