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Diethylcarbamazine is used to treat the following -
Main Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
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Geriatric |
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Based on research, the following side effects have been observed when Diethylcarbamazine is used -
Severe
Mild
Is the use of Diethylcarbamazine safe for pregnant women?
Diethylcarbamazine has many dangerous side effects in pregnant women. If you are pregnant, do not consume Diethylcarbamazine without medical advice.
Is the use of Diethylcarbamazine safe during breastfeeding?
No research work has been carried out till date on effect of Diethylcarbamazine on breastfeeding women. So it is not known whether taking Diethylcarbamazine will cause side effects or not.
What is the effect of Diethylcarbamazine on the Kidneys?
Kidney can be affected by Diethylcarbamazine. If you experience any unwanted effects of this drug, stop taking it. You should take it again only after medical advice.
What is the effect of Diethylcarbamazine on the Liver?
Diethylcarbamazine has very mild side effects on the liver.
What is the effect of Diethylcarbamazine on the Heart?
There may be an adverse effect on the heart after taking Diethylcarbamazine. If you observe any side effects on your body then stop taking this drug. Restart this medicine only if your doctor advises you to do so.
Diethylcarbamazine should not be taken with following medicines due to severe side effects it may cause to patients -
Moderate
If you are suffering from any of the following diseases, you should not take Diethylcarbamazine unless your doctor advises you to do so -
Is this Diethylcarbamazine habit forming or addictive?
Diethylcarbamazine is not addictive in nature.
Is it safe to drive or operate heavy machinery when consuming?
Yes, you can comfortably use machinery or drive after taking Diethylcarbamazine since it will not make you feel sleepy.
Is it safe?
Diethylcarbamazine should be used only after doctor's advice.
Is it able to treat mental disorders?
No, Diethylcarbamazine cannot treat any kind of mental disorder.
Interaction between Food and Diethylcarbamazine
There isn't any research available on the side effects of taking Diethylcarbamazine with food.
Interaction between Alcohol and Diethylcarbamazine
Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Diethylcarbamazine.
Diethylcarbamazine when used against the microfilariae of o.vulvus in skin and eye can cause permanent damage due to the reactions like uveitis (swelling of the middle layer of the eye), punctuate keratitis (death of cells on the surface of the cornea) and retinal pigment epithelium atrophy (degeneration of retinal pigment epithelium).
Diethylcarbamazine alters the muscular activity of the filaria, also alters its surface membranes making it more susceptible to the host. The destruction of organisms and release of antigens can lead to toxicity and produce an inflammatory reaction which may be present in the form of severe itching, rash, edema, hypotension, fever, presence of protein in urine, painful joints, swollen or enlarged lymph nodes, and abnormal enlargement of the spleen. These complications can be lessened by pre-treatment with corticosteroids.
Diethylcarbamazine side effects can be minimized by a simultaneous administration of an antihistamine or a corticosteroid. Due to the destruction of a large number of microfilariae, there is a risk of renal and central nervous system complications. This risk can be minimized by withholding the treatment with an anthelmintic drug, removal of microfilariae before the administration of Diethylcarbamazine and administering a single dose of ivermectin.
Yes, Diethylcarbamazine may cause an allergic reaction. Call your doctor immediately if you suffer from any kind of an allergic reaction. Also inform your doctor if you are allergic to any food, preservative, dye or an animal.
Diethylcarbamazine belongs to a group of medicines known as anthelmintics which are used against the parasitic worms. It is used against the larval and adult forms of parasitic worms which give rise to lymphatic filariasis. Lymphatic filariasis is a disorder in which the legs, arms, male genitals and female breasts may get swollen and disfigured. It kills adult worms of Wuchereria bancrofti, Brugia malayi and B. timori. It is also used against topical pulmonary eosinophilia [Also known as Loeffler syndrome, pulmonary eosinophilia is a temporary and a rare disorder characterized by the accumulation of eosinophils (a type of white blood cells) in the lungs] and loiasis (Also known as African eye worm, loiasis is caused by parasite Loa loa. The parasite is passed on to humans through the repeated bites of the deer flies). The infection leads to itchy swellings of the body.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 853