Mefipil

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₹ 329
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  • Contains / Salt: Mifepristone (200 mg)
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Mefipil Information

Mefipil is a commercial drug that is prescribed in the form of Tablet. It is typically used for the treatment of Abortion. Mefipil also has some secondary and off-label uses. These are listed below.

The correct dosage of Mefipil depends on the patient's age, gender, and medical history. The condition it has been prescribed for, and the route of administration also determine the right dosage. This information has been provided in detail in the dosage section.

The most common side effects of Mefipil are Uterine Cramps, Uterine Bleeding. Apart from the aforementioned side effects, Mefipil can also lead to other problems, which have been listed below. Such side effects of Mefipil normally do not last long and go away once the treatment is completed. If, however, they worsen or do not go away, please speak with your physician.

Furthermore, you should know that effect of Mefipil is Severe for pregnant women and Moderate for women who are breastfeeding. Warnings related to Mefipil's effects on the liver, heart and kidney, if any, have been listed below.

Mefipil can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Mefipil in conditions like Bleeding, Porphyria, Diabetes. Other conditions have been mentioned below in the Mefipil contraindications section.

Besides this, Mefipil may also have severe interaction with some medicines. A complete list of these interactions is given below.

You should also be aware that Mefipil is not safe while driving, and is not addiction.



Mefipil Benefits & Uses

Mefipil is used to treat the following -

Main Benefits

  • Abortion

Other Benefits

Mefipil Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Cushing's Syndrome
  • Before or After Meal: With meal
  • Single Maximum Dose: 300 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Cushing's Syndrome
  • Before or After Meal: With meal
  • Single Maximum Dose: 300 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult(Female)
  • Disease: Abortion
  • Before or After Meal: Either
  • Single Maximum Dose: 200 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: once only
  • Course Duration: 3 days
  • Special Instructions: 24 to 48 hrs after 1st dose patient should place two 200 mcg misoprostol tablets in each cheek pouch and swallow it after 30min


Mefipil Side Effects

Based on research, the following side effects have been observed when Mefipil is used -

Severe

Moderate

Mild

Common

  • Uterine Cramps
  • Uterine Bleeding

Mefipil Related Warnings

  • Is the use of Mefipil safe for pregnant women?


    Mefipil shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

    Severe
  • Is the use of Mefipil safe during breastfeeding?


    Mefipil may lead to some side effects in breastfeeding women. If you witness any unusal symptoms after taking Mefipil, discontinue its use and call your doctor right away. Follow your doctor's advice regarding the use of Mefipil.

    Moderate
  • What is the effect of Mefipil on the Kidneys?


    Mefipil rarely harms the kidneys.

    Mild
  • What is the effect of Mefipil on the Liver?


    Mefipil can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Mefipil on the Heart?


    Very few cases of side effects of Mefipil on the heart have been reported.

    Mild


Severe Interaction of Mefipil with Other Drugs

Mefipil should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate

Mild



Mefipil Contraindications

If you are suffering from any of the following diseases, you should not take Mefipil unless your doctor advises you to do so -



Frequently asked Questions about Mefipil

  • Is this Mefipil habit forming or addictive?


    Mefipil is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should do not do anything that requires concentration and attention as the Mefipil can make you feel drowsy.

    Dangerous
  • Is it safe?


    Yes, but take Mefipil only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Mefipil cannot treat any kind of mental disorder.

    No

Mefipil Interactions with Food and Alcohol

  • Interaction between Food and Mefipil


    Due to a lack of research, nothing can be said about the consequences of taking Mefipil together with food.

    Unknown
  • Interaction between Alcohol and Mefipil


    No research has been done on this till date. Therefore, it is not known what the effect of taking Mefipil with alcohol will be.

    Unknown


Frequently asked Questions about Mefipil

Question about 5 years ago

Does Mefipil cause birth defects?

Dr. Madhur Anand MBBS, MS , General Surgery

Yes, If abortion has not happened after taking this Mefipil. You are highly recommended to take a doctor's advise because this drug may cause teratogenic (birth defects of mental & physical) origin in the unborn fetus.

Question about 5 years ago

Is Mefipil safe to use?

Dr. Haleema Yezdani MBBS , General Physician

Yes, Mefipil is safe to use, if taken in a prescribed amount for a specified time as advised by the doctor. However, few side effects such as diarrhea, pelvic pain, weakness, and fever may occur. 

Question about 5 years ago

What is Mefipil?

Dr. Amit Singh MBBS , General Physician

Mefipil is a brand name of mifepristone, also known as an abortion pill. It belongs to the class of synthetic steroids, which has antiprogesterone and antiglucocorticoid properties. It is used in combination with misoprostol to result in abortion. It is also used in the treatment of Cushing syndrome.

Question over 4 years ago

Can I take Mefipil on empty stomach?

Yes, you can take Mefipil on empty stomach. It does not irritate the stomach lining if taken in an empty stomach. However, it is best to consult your doctor 

Question over 4 years ago

Can I take Mefipil with Ibuprofen?

Dr. Abhijit MBBS , General Physician

Yes, you can take Mefipil with ibuprofen, no harmful interaction reported between them. However, It's doesn't mean that no interaction exists between them. Before taking such kind of combination you always consult your doctor.



See all substitutes for Mefipil


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 858-859

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 319-320

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Mifeprex® (mifepristone)



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