Methotrexate: Uses, Price, Dosage, Side Effects, Substitute, Buy Online

Methotrexate Benefits

Methotrexate is used to treat the following -

Other Benefits

Rheumatoid Arthritis
Psoriasis (Read More - Home remedies for psoriasis)

Methotrexate Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: B-Cell Acute Lymphoblastic Leukemia Before or After Meal: Either Single Maximum Dose: 5 mg Dosage Form: Tablet Dosage Route: Oral Frequency: 1 daily Course Duration: As directed by the doctor Special Instructions: As prescribed by the doctor
Geriatric	Disease: B-Cell Acute Lymphoblastic Leukemia Before or After Meal: Either Single Maximum Dose: 5 mg Dosage Form: Tablet Dosage Route: Oral Frequency: 1 daily Course Duration: As directed by the doctor Special Instructions: As prescribed by the doctor

Methotrexate Side Effects

Based on research, the following side effects have been observed when Methotrexate is used -

Moderate

Stomatitis (Inflammation of the mouth)

Mild

Nausea or vomiting
Loss of appetite
Diarrhoea
Joint pain
Photosensitivity
Hair Loss
Dizziness
Itching or burning
Rash
Headache
Infection
Fever (Read More - Home remedies for fever)
Cough

Common

पेट दर्द

Methotrexate Related Warnings

Is the use of Methotrexate safe for pregnant women?

Methotrexate shows severe effect on pregnant women. For this reason, take it after medical advice only. Taking it with your desire can be harmful.

Severe
Is the use of Methotrexate safe during breastfeeding?

Methotrexate may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

Severe
What is the effect of Methotrexate on the Kidneys?

Kidney can be affected by Methotrexate. If you experience any unwanted effects of this drug, stop taking it. You should take it again only after medical advice.

Moderate
What is the effect of Methotrexate on the Liver?

You may experience side effects on your liver after taking Methotrexate. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.

Moderate
What is the effect of Methotrexate on the Heart?

Methotrexate has very mild side effects on the heart.

Mild

Severe Interaction of Methotrexate with Other Drugs

Methotrexate should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Omeprazole

Esomeprazole

Rotavirus Vaccine (Live Attenuated)

Moderate

Ketoconazole

Atorvastatin

Paracetamol,Chlorpheniramine,Dextromethorphan

Methotrexate Contraindications

If you are suffering from any of the following diseases, you should not take Methotrexate unless your doctor advises you to do so -

Infections
Allergy
Liver Disease
Anemia
Kidney Disease
Mouth Ulcer

How to use Methotrexate?

General precautions for Methotrexate

Frequently asked Questions about Methotrexate

Question over 4 years ago

Can Methotrexate cure rheumatoid arthritis?

Dr. Manoj Meena MBBS , General Physician

Unfortunately, there is no such drug available till now that can cure rheumatoid arthritis. Methotrexate is effectively used in combination with other drugs to relieve the symptoms that associated with rheumatoid arthritis such as pain and swelling.

Question about 4 years ago

Is Methotrexate a steroid?

Dr. MBBS , Dermatology, General Physician, Dietician, Infectious Disease, Sexual Medicine & Marital Therapy, Obstetrics & Gynaecology, AIDS/HIV Sexually Transmitted Infections

No, Methotrexate is not a steroid. It is an antimetabolite (a chemotherapy drug) and disease-modifying antirheumatic drug (DMARDs) which have immunosuppressant properties. It is used in the treatment of various types of cancer and other diseases such as psoriasis, rheumatoid arthritis, and Crohn's disease.

Question over 4 years ago

Can Methotrexate cause hair loss?

Dr. Suhas Bhargav MBBS , General Physician

Yes, Methotrexate causes hair loss (alopecia). It is a known side effect of this drug. This side effect is reversible in nature and it is resolved after the discontinuation of this drug.

Question almost 4 years ago

Can I take Methotrexate with paracetamol?

Dr. Uday Nath Sahoo MBBS , Internal Medicine

Yes Methotrexate can be taken with paracetamol. Paracetamol does not appear to interfere with the efficacy of Methotrexate. Hence, it is alright to take them together. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.

Question almost 5 years ago

Can Methotrexate cause drowsiness?

Dr. Chinmaya Bal MBBS , General Physician

Yes, Methotrexate may cause drowsiness and dizziness in a few cases only. It is a rare side effect of this medicine. However, the exact cause of drowsiness is not known.