Metsafe

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10 Tablet in 1 Strip Out of Stock
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10 TABLET 1 Strip ₹ 28
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  • Contains / Salt: Metformin (1000 mg)
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Metsafe Information

Metsafe, a prescription drug, is manufactured in various forms such as Tablet. It is typically used for the treatment of Diabetes.

Medical history of the patient along with age and gender determines the dosage of Metsafe. Individual symptoms and route of administration also determines the right dosage. For detailed information on this, read through the dosage section.

The most common side effects of Metsafe are Stomach Upset, Difficulty urinating. Some other side effects of Metsafe have been listed ahead. Normally, these side effects of Metsafe are not long lasting and go away when the treatment is finished. Please speak with your doctor if these side effects worsen or persist for a longer duration.

It is also important to note that Metsafe has a Mild effect for pregnant women and Moderate effect on lactating mothers. Further, the section on Metsafe related warnings talks about Metsafe's effects on the liver, heart and kidney.

Metsafe can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Metsafe in conditions like Congestive Heart Failure (CHF), Anemia, Shock. The section on Metsafe contraindications lists all such conditions.

Drug reaction of Metsafe with other medicines has been reported. See below for a complete list.

In addition to the above precautions for Metsafe, it is important to know that it is safe while driving, and is habit-forming.



Metsafe Benefits & Uses

Metsafe is used to treat the following -

Main Benefits

Metsafe Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 500 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 500 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 500 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 500 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor


Metsafe Side Effects

Based on research, the following side effects have been observed when Metsafe is used -

Severe

  • Blurred vision

Moderate

Mild

  • Nausea or vomiting
  • Altered taste
  • Diarrhoea
  • पेट दर्द
  • Loss of appetite
  • Headache
  • पेट की गैस
  • Dyspepsia

Common

  • Stomach Upset
  • Difficulty urinating

Metsafe Related Warnings

  • Is the use of Metsafe safe for pregnant women?


    Metsafe has mild to no side effects in pregnant women.

    Mild
  • Is the use of Metsafe safe during breastfeeding?


    Breastfeeding women may feel side effects of Metsafe. If you see any side effects, stop taking Metsafe immediately and talk to your doctor. Take Metsafe again, only after your doctor's advice.

    Moderate
  • What is the effect of Metsafe on the Kidneys?


    Metsafe does not damage the kidneys.

    Safe
  • What is the effect of Metsafe on the Liver?


    Metsafe is not harmful for the liver.

    Safe
  • What is the effect of Metsafe on the Heart?


    You can take Metsafe without any fear of damage to the heart.

    Safe


Severe Interaction of Metsafe with Other Drugs

Metsafe should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Metsafe Contraindications

If you are suffering from any of the following diseases, you should not take Metsafe unless your doctor advises you to do so -



Frequently asked Questions about Metsafe

  • Is this Metsafe habit forming or addictive?


    Metsafe does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can comfortably use machinery or drive after taking Metsafe since it will not make you feel sleepy.

    Safe
  • Is it safe?


    Metsafe should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Metsafe cannot treat any kind of mental disorder.

    No

Metsafe Interactions with Food and Alcohol

  • Interaction between Food and Metsafe


    There is no information on the effects of taking Metsafe with food, because this topic has not been scientifically researched yet.

    Unknown
  • Interaction between Alcohol and Metsafe


    Consult your doctor before consuming alcohol while taking Metsafe as it can have severe side effects.

    Severe


Frequently asked Questions about Metsafe

Question almost 5 years ago

Does Metsafe cause sweating?

Dr. Joydeep Sarkar MBBS , Internal Medicine

Yes, Metsafe can cause night sweat, the exact mechanism of sweating is not known. But some research suggests that Metsafe causes hypoglycemia (low blood sugar) especially at night which can cause night sweats. Need to monitor your blood glucose level regularly, and talk to your doctor as your dose of Metsafe may need to be adjusted.

Question about 5 years ago

How long should I take Metsafe for?

Dr. Ram Saini MD, MBBS , General Physician

Metsafe can be taken forever, diabetes is a progressive disease it's possible that more medication and/or insulin may eventually need to be added to the regime. 

Question over 4 years ago

How does Metsafe increase lactic acidosis?

Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with Metsafe treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Metsafe induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst. 

Question about 5 years ago

How does Metsafe work?

Dr. Rahul Poddar MBBS, DNB, MBBS, DNB , General Surgery

Metsafe works by decreasing the hepatic glucose production. It also works to lower blood sugar by increasing your sensitivity to insulin and decreasing the amount of glucose that is absorbed from the food you eat.

Question over 4 years ago

Does Metsafe cause stomach ulcers?

Dr. Mayank Yadav MBBS , General Physician

Yes, Metsafe commonly cause stomach upset like diarrhea, abdominal pain, nausea, and vomiting. To avoid these side effects you should take Metsafe with your meal and increase the dose gradually.



See all substitutes for Metsafe


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glucophage® (metformin hydrochloride)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275-276

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 825-826

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