Topgraf

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Topgraf Information

Topgraf, a prescription drug, is manufactured in various forms such as Ointment. It is primarily used for the treatment of Liver transplant, Kidney transplant, Heart Transplant. Other than this, Topgraf has some other therapeutic uses, which have been discussed ahead.

The correct dosage of Topgraf depends on the patient's age, gender, and medical history. The condition it has been prescribed for, and the route of administration also determine the right dosage. Refer to the dosage section for a detailed discussion.

Apart from the aforementioned side effects, Topgraf can also lead to other problems, which have been listed below. These side effects of Topgraf are usually temporary and subside with the completion of treatment. Please speak with your doctor if these side effects worsen or persist for a longer duration.

Topgraf's effect during pregnancy is Moderate and Moderate while nursing. It is important to know if Topgraf has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Topgraf related warnings section.

Topgraf is not recommended if you suffer from certain medical conditions as it can have adverse effects. Infections, Diabetes Type 2 are examples of such conditions. Other contraindications of Topgraf have been discussed in the sections ahead.

Additionally, Topgraf may also adversely react with other medicines. See below for a complete list.

In addition to these precautions, you may also note that Topgraf is safe while driving, and is is addictive in nature.



Topgraf Benefits & Uses

Topgraf is used to treat the following -

Main Benefits

Other Benefits

Topgraf Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Atopic Dermatitis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: Apply in appropriate quantity on affected area
  • Dosage Form: Ointment
  • Dosage Route: Topical
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice
Geriatric
  • Disease: Atopic Dermatitis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: Apply in appropriate quantity on affected area
  • Dosage Form: Ointment
  • Dosage Route: Topical
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice
13 - 18 years (Adolescent)
  • Disease: Atopic Dermatitis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: Apply in appropriate quantity on affected area
  • Dosage Form: Ointment
  • Dosage Route: Topical
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice
2 - 12 years (Child)
  • Disease: Atopic Dermatitis
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: Apply in appropriate quantity on affected area
  • Dosage Form: Ointment
  • Dosage Route: Topical
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice

Topgraf Related Warnings

  • Is the use of Topgraf safe for pregnant women?


    Topgraf may cause moderate side effects during pregnancy. If you feel its harmful effects, then stop taking this drug immediately, and do not take Topgraf again without your doctor's advice.

    Moderate
  • Is the use of Topgraf safe during breastfeeding?


    Topgraf may lead to some side effects in breastfeeding women. If you witness any unusal symptoms after taking Topgraf, discontinue its use and call your doctor right away. Follow your doctor's advice regarding the use of Topgraf.

    Moderate
  • What is the effect of Topgraf on the Kidneys?


    Topgraf can have moderate side effects on the kidney. If you notice any harmful effects, stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Topgraf on the Liver?


    Topgraf can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Topgraf on the Heart?


    Use of Topgraf may be dangerous for the heart. Do not use it without doctor's advice.

    Severe


Severe Interaction of Topgraf with Other Drugs

Topgraf should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Topgraf Contraindications

If you are suffering from any of the following diseases, you should not take Topgraf unless your doctor advises you to do so -



Frequently asked Questions about Topgraf

  • Is this Topgraf habit forming or addictive?


    Topgraf is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Topgraf does not cause dizziness or sleep, so you can drive a vehicle or operate machinery also.

    Safe
  • Is it safe?


    Topgraf is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Topgraf is not used to treat mental disorders.

    No

Topgraf Interactions with Food and Alcohol

  • Interaction between Food and Topgraf


    Due to the absence of research, it is difficult to say how Topgraf and food will interact.

    Unknown
  • Interaction between Alcohol and Topgraf


    Consult your doctor before consuming alcohol while taking Topgraf as it can have severe side effects.

    Severe


Frequently asked Questions about Topgraf

Question about 5 years ago

How does Topgraf work?

Dr. Vinod Verma MBBS , Diabetology

Topgraf work by reducing the activity of the immune system so it cannot attack the transplanted organ. Hence in this way, it prevents the rejection of organ transplants.

Question over 4 years ago

Can Topgraf cause hair loss?

Dr. Vipin Khadse MBBS , General Physician

Yes, Topgraf may cause hair loss. The patients who are taking this drug are at risk of alopecia (hair loss). If you are experiencing the same after taking this drug, you are advised to consult about it with your doctor immediately.

Question about 5 years ago

Can I discontinue Topgraf on my own without doctors advice?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

Yes, you can discontinue the Topgraf once you get the relief from burns. You are recommended to consult a doctor before discontinuing this medicine.

Question almost 5 years ago

Is Topgraf safe to use?

Dr. Uday Nath Sahoo MBBS , Internal Medicine

Yes, Topgraf is safe to use, if taken in prescribed amount and duration as advised by the doctor. However, certain side effects have been associated with this drug such as headache, diarrhea, constipation, nausea, vomiting. If you experience any discomfort after taking this do inform your doctor.

Question over 4 years ago

Can Topgraf cause headache?

Dr. Abhijit MBBS , General Physician

Yes, Topgraf may cause a headache. It has been reported by the patients who are taking this drug. If you are experiencing the same after taking this drug, you are advised to consult about it with your doctor.



See all substitutes for Topgraf


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Prograf® (tacrolimus)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 881

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1165-1167

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