Topril

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Topril Information

Topril is a commercial drug that is prescribed in the form of Capsule. It is primarily used for the treatment of High BP. Topril also has some secondary and off-label uses. These are listed below.

Medical history of the patient along with age and gender determines the dosage of Topril. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Detailed information has been provided in the dosage section.

The most common side effects of Topril are Confusion. While these are the most often observed Topril side effects, there are can be others also. These have been listed below. These side effects of Topril are usually temporary and subside with the completion of treatment. If, however, they worsen or do not go away, please speak with your physician.

In addition, Topril's effect is Severe during pregnancy and Mild for lactating mothers. Warnings related to Topril's effects on the liver, heart and kidney, if any, have been listed below.

Topril is not recommended if you suffer from certain medical conditions as it can have adverse effects. Angioedema, Heart Failure, Low Blood Pressure (Hypotension) are examples of such conditions. Some other conditions that can be affected by Topril are listed in the contraindications section below.

Besides this, Topril may also have severe interaction with some medicines. A complete list of these interactions is given below.

Along with the above-mentioned precautions, remember that taking Topril is considered not safe while driving, and is not addictive.



Topril Benefits & Uses

Topril is used to treat the following -

Main Benefits

Other Benefits

Topril Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: High Blood Pressure
  • Before or After Meal: After Meal
  • Single Maximum Dose: 2.5 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dose slowly may increase up to 20 mg/day
Geriatric
  • Disease: High Blood Pressure
  • Before or After Meal: After Meal
  • Single Maximum Dose: 2.5 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dose slowly may increase up to 20 mg/day

Topril Related Warnings

  • Is the use of Topril safe for pregnant women?


    Topril shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

    Severe
  • Is the use of Topril safe during breastfeeding?


    Topril may have very limited harmful effects for breastfeeding women.

    Mild
  • What is the effect of Topril on the Kidneys?


    Topril has very mild side effects on the kidneys.

    Mild
  • What is the effect of Topril on the Liver?


    Very few cases of side effects of Topril on the liver have been reported.

    Mild
  • What is the effect of Topril on the Heart?


    Topril has very mild side effects on the heart.

    Mild


Severe Interaction of Topril with Other Drugs

Topril should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate

Chlorpheniramine,Dextromethorphan,Paracetamol,Phenylephrine
    Amitriptyline


    Topril Contraindications

    If you are suffering from any of the following diseases, you should not take Topril unless your doctor advises you to do so -



    Frequently asked Questions about Topril

    • Is this Topril habit forming or addictive?


      No, there is no any evidence that Topril is addictive.

      No
    • Is it safe to drive or operate heavy machinery when consuming?


      You may feel sleepy or tired after taking Topril. So it is best to avoid driving.

      Dangerous
    • Is it safe?


      Topril should be used only after doctor's advice.

      Safe, but take only on Doctor's advise
    • Is it able to treat mental disorders?


      Topril is unable to treat or cure mental disorders.

      No

    Topril Interactions with Food and Alcohol

    • Interaction between Food and Topril


      Taking Topril with some specific foods may delay its effect. Talk to your doctor about this.

      Mild
    • Interaction between Alcohol and Topril


      No research has been done on this till date. Therefore, it is not known what the effect of taking Topril with alcohol will be.

      Unknown


    Frequently asked Questions about Topril

    Question over 4 years ago

    Can I take Topril with telmisartan?

    Dr. OP Kholwad MBBS , General Physician

    Yes, Topril can be taken with telmisartan. As per clinical studies, no harmful interaction has been reported after taking them. However, do not take it without doctors advise. A fixed-dose combination of [Medicinie] and telmisartan is available in the market which is used in the treatment of hypertension (high blood pressure).

    Question about 5 years ago

    How long can I safely take Topril?

    Dr. , General Physician

    Take Topril as directed by your doctor. Do not discontinue the drug suddenly or take it longer than prescribed by your doctor.

    Question about 5 years ago

    Can I take Topril without consulting a doctor?

    Dr. K. M. Bhatt MBBS, PG Dip , Cardiology, Pediatrics, General Surgery, General Physician, Emergency Medicine, Physical Medicine

    Topril is a prescription drug so do not take it without consulting a doctor. It can be harmful for the patient to take this medicine without a doctor's recommendation.

    Question almost 5 years ago

    Does Topril cause erectile dysfunction?

    Dr. R.K Singh MBBS , Diabetology

    Yes, Topril may cause erectile dysfunction. It is an uncommon side effect of this drug. If you experience erectile dysfunction after consuming this drug, please inform a doctor, they might give you alternate treatment.

    Question over 4 years ago

    Does Topril cause arrhythmia (Irregular heart beat)?

    Dr. Ashish Mishra MBBS , Pathology

    Rarely, Topril causes arrhythmia (Irregular heartbeat). However, if you experience any fluctuation in heart rate after consuming this drug, please inform a doctor and follow his/her instructions.



    See all substitutes for Topril


    This medicine data has been created by -

    Vikas Chauhan

    B.Pharma, Pharmacy
    5 Years of Experience


    References

    US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Altace (ramipril)

    April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 163-169

    KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 503

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