Tvaptan

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Tvaptan Information

Tvaptan, a prescription drug, is manufactured in various forms such as Tablet. It is typically used for the treatment of Inappropriate Antidiuretic Hormone Secretion.

The optimal dosage of Tvaptan is largely dependent on the individual's body weight, medical history, gender and age. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Refer to the dosage section for a detailed discussion.

The most common side effects of Tvaptan are Increased thirst, Weakness. Some other side effects of Tvaptan have been listed ahead. Usually, these side effects of Tvaptan go away soon, and do not persist beyond the duration of the treatment. If, however, they worsen or do not go away, please speak with your physician.

It is also important to note that Tvaptan has a Severe effect for pregnant women and Severe effect on lactating mothers. Further, the section on Tvaptan related warnings talks about Tvaptan's effects on the liver, heart and kidney.

Tvaptan can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Tvaptan in conditions like Liver Disease, Kidney Disease, Hyperkalemia.

Besides this, Tvaptan may also have severe interaction with some medicines. A complete list of these interactions is given below.

In addition to these precautions, you may also note that Tvaptan is not safe while driving, and is is not addictive in nature.



Tvaptan Benefits & Uses

Tvaptan is used to treat the following -

Other Benefits

Tvaptan Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Inappropriate Antidiuretic Hormone Secretion (SIADH)
  • Before or After Meal: Either
  • Single Maximum Dose: 15 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 1 months
  • Special Instructions: gradually increases upto 60 mg/day
Geriatric
  • Disease: Inappropriate Antidiuretic Hormone Secretion (SIADH)
  • Before or After Meal: Either
  • Single Maximum Dose: 15 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 1 months
  • Special Instructions: gradually increases upto 60 mg/day

Tvaptan Related Warnings

  • Is the use of Tvaptan safe for pregnant women?


    Tvaptan should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.

    Severe
  • Is the use of Tvaptan safe during breastfeeding?


    Tvaptan may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

    Severe
  • What is the effect of Tvaptan on the Kidneys?


    Tvaptan has very mild side effects on the kidneys.

    Mild
  • What is the effect of Tvaptan on the Liver?


    Tvaptan is not harmful for the liver.

    Safe
  • What is the effect of Tvaptan on the Heart?


    You can take Tvaptan without any fear of damage to the heart.

    Safe


Severe Interaction of Tvaptan with Other Drugs

Tvaptan should not be taken with following medicines due to severe side effects it may cause to patients -

Severe



Tvaptan Contraindications

If you are suffering from any of the following diseases, you should not take Tvaptan unless your doctor advises you to do so -



Frequently asked Questions about Tvaptan

  • Is this Tvaptan habit forming or addictive?


    Tvaptan does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Tvaptan, you should not drive or work on any heavy machine, as Tvaptan can make you drowsy.

    Dangerous
  • Is it safe?


    Tvaptan is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Tvaptan is unable to treat or cure mental disorders.

    No

Tvaptan Interactions with Food and Alcohol

  • Interaction between Food and Tvaptan


    Tvaptan may take longer to act if you eat some foods while taking it. Follow your doctor's advice on this.

    Mild
  • Interaction between Alcohol and Tvaptan


    Consumption of alcohol and Tvaptan together may have severe effects on your health.

    Severe


See all substitutes for Tvaptan


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1216-1217

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 525

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Samsca® (tolvaptan)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Jynarque (tolvaptan)



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