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Clokit, a prescription drug, is manufactured in various forms such as Tablet. It is primarily used for the treatment of Malaria.
The optimal dosage of Clokit is largely dependent on the individual's body weight, medical history, gender and age. The condition it has been prescribed for, and the route of administration also determine the right dosage. This information has been provided in detail in the dosage section.
Some other side effects of Clokit have been listed ahead. Usually, these side effects of Clokit go away soon, and do not persist beyond the duration of the treatment. Consult your doctor if these side effects become worse or stay for a longer duration.
It is also important to note that Clokit has a Severe effect for pregnant women and Severe effect on lactating mothers. Further, the section on Clokit related warnings talks about Clokit's effects on the liver, heart and kidney.
Individuals suffering from medical conditions like Porphyria must refrain from the use of Clokit since this can cause severe adverse effects. Other contraindications of Clokit have been discussed in the sections ahead.
Additionally, Clokit may also adversely react with other medicines. See below for a complete list.
In addition to these precautions, you may also note that Clokit is not safe while driving, and is is not addictive in nature.
Clokit is used to treat the following -
Main Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
13 - 18 years (Adolescent) |
|
2 - 12 years (Child) |
|
Infant (1 month to 2 years) |
|
Based on research, the following side effects have been observed when Clokit is used -
Is the use of Clokit safe for pregnant women?
Clokit has many dangerous side effects in pregnant women. If you are pregnant, do not consume Clokit without medical advice.
Is the use of Clokit safe during breastfeeding?
Women who are breastfeeding may experience severe harmful effects after taking Clokit. It should only be taken after medical advice.
What is the effect of Clokit on the Kidneys?
Clokit can have moderate side effects on the kidney. If you notice any harmful effects, stop taking this drug right away. Consult your doctor before using this medicine again.
What is the effect of Clokit on the Liver?
There may be an adverse effect on the liver after taking Clokit. If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.
What is the effect of Clokit on the Heart?
There may be an adverse effect on the heart after taking Clokit. If you observe any side effects on your body then stop taking this drug. Restart this medicine only if your doctor advises you to do so.
Clokit should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Clokit unless your doctor advises you to do so -
Is this Clokit habit forming or addictive?
No, you will not get addicted to Clokit.
Is it safe to drive or operate heavy machinery when consuming?
After taking Clokit, you should not drive or work on any heavy machine, as Clokit can make you drowsy.
Is it safe?
Yes, but consume Clokit only on doctor's advice.
Is it able to treat mental disorders?
No, Clokit is not used to treat mental disorders.
Interaction between Food and Clokit
There is no information on the effects of taking Clokit with food, because this topic has not been scientifically researched yet.
Interaction between Alcohol and Clokit
It is difficult to say anything about the effect of Clokit and alcohol. No research has been done on this yet.
Yes, long-term use of Clokit may cause weight loss but this occurs rarely. It is a rare side effect of Clokit. However, if you are experiencing unusual rapid weight loss and you are in doubt that Clokit is causing weight loss then discuss with your doctor instantly.
Clokit contains chloroquine. It has antimalarial, amebicidal, and immunosuppressant activity. It is presumed that Clokit works by increasing pH in the acid vesicles of parasite which interferes in the parasite's ability to break down and digest hemoglobin. Malarial parasites need hemoglobin for growth and survival. This results in starvation and death of parasites. Clokit works in rheumatoid arthritis and systemic lupus erythematosus (SLE) by suppressing the immune system which provides relief to the patient from pain and inflammation. However, the exact mechanism how it works in these autoimmune diseases is still unknown.
Clokit is a brand name of chloroquine and it comes in the form of a tablet, capsule, injection, and oral suspension. It belongs to the class of drugs known as antimalarials which have amebicidal activity. It is a prescription drug that is used in the treatment of malaria which is a vector-borne infectious disease caused by parasites Plasmodium species. These are Plasmodium falciparum, Plasmodium malariae, Plasmodium ovale, and Plasmodium vivax. Apart from this Clokit is also used in the treatment of extraintestinal amebiasis which is the protozoal infection caused by parasite Entamoeba histolytica. It is also used in the treatment of rheumatoid arthritis and systemic lupus erythematosus (SLE) both are autoimmune diseases which causes inflammation and pain. Clokit is also used off-label for the treatment of porphyria cutanea tarda (PCT) a blood disorder that affects the skin.
Rarely, Clokit causes hair loss (alopecia). This problem goes away after discontinuation of this drug. For partial hair loss, you are advised to use hair tonic and discuss with the doctor for best possible treatment to hair loss.
Yes Clokit can be taken with aspirin. Aspirin does not appear to interfere with the efficacy of Clokit. Hence, it is best to take them together. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
KD Tripathi. Package leaflet information for the user; Aralen® Chloroquine phosphate. Eighth Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2019
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 211