Doxorubicin

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Doxorubicin Information

Doxorubicin is a commercial drug that is prescribed in the form of Injection. It is primarily used for the treatment of Blood Cancer. Other than this, Doxorubicin has some other therapeutic uses, which have been discussed ahead.

The right dosage of Doxorubicin depends on the age, gender, and medical history of the patient. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Detailed information has been provided in the dosage section.

The most common side effects of Doxorubicin are Hair Loss. Some other side effects of Doxorubicin have been listed ahead. Such side effects of Doxorubicin normally do not last long and go away once the treatment is completed. Please speak with your doctor if these side effects worsen or persist for a longer duration.

Furthermore, you should know that effect of Doxorubicin is Severe for pregnant women and Severe for women who are breastfeeding. It is important to know if Doxorubicin has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Doxorubicin related warnings section.

Doxorubicin is not recommended if you suffer from certain medical conditions as it can have adverse effects. Heart Failure are examples of such conditions. The section on Doxorubicin contraindications lists all such conditions.

Besides this, Doxorubicin may also have severe interaction with some medicines. A complete list of these interactions is given below.

You should also be aware that Doxorubicin is not safe while driving, and is not addiction.



Doxorubicin Benefits & Uses

Doxorubicin is used to treat the following -

Main Benefits

Other Benefits

Doxorubicin Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Blood Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 110 mg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult(Female)
  • Disease: Breast Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 110 mg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Blood Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 110 mg
  • Dosage Route: Parenteral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor


Doxorubicin Side Effects

Based on research, the following side effects have been observed when Doxorubicin is used -

Moderate

  • Stomatitis (Inflammation of the mouth)
  • Decreased Blood Cells (Red cells, White cells and Platelets)

Mild

Common

Doxorubicin Related Warnings

  • Is the use of Doxorubicin safe for pregnant women?


    Pregnant women may get severe side effects after taking Doxorubicin. If you are pregnant, do not take Doxorubicin without a doctor's advice.

    Severe
  • Is the use of Doxorubicin safe during breastfeeding?


    Doxorubicin may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

    Severe
  • What is the effect of Doxorubicin on the Kidneys?


    There are no side effects of Doxorubicin on the kidneys.

    Safe
  • What is the effect of Doxorubicin on the Liver?


    The liver can be affected by Doxorubicin. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Doxorubicin only after medical advice.

    Moderate
  • What is the effect of Doxorubicin on the Heart?


    You may experience side effects on your heart after taking Doxorubicin. If this happens, then discontinue its use. Consult your medical practitioner, and do as he/she suggests.

    Moderate


Severe Interaction of Doxorubicin with Other Drugs

Doxorubicin should not be taken with following medicines due to severe side effects it may cause to patients -

Severe



Doxorubicin Contraindications

If you are suffering from any of the following diseases, you should not take Doxorubicin unless your doctor advises you to do so -



Frequently asked Questions about Doxorubicin

  • Is this Doxorubicin habit forming or addictive?


    No, there is no any evidence that Doxorubicin is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should not drive or operate heavy machinery after taking Doxorubicin as you may feel sleepy.

    Dangerous
  • Is it safe?


    Doxorubicin should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Doxorubicin for mental disorders.

    No

Doxorubicin Interactions with Food and Alcohol

  • Interaction between Food and Doxorubicin


    Taking Doxorubicin with food is safe.

    Safe
  • Interaction between Alcohol and Doxorubicin


    Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Doxorubicin.

    Unknown


See all substitutes for Doxorubicin


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 463-465

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 867

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Adriamycin (doxorubicin hydrochloride)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Doxorubicin Hydrochloride (doxorubicin hydrochloride)



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