Mifeprin

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  • Contains / Salt: Mifepristone (200 mg)
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Mifeprin Information

Mifeprin is a prescription medicine that is available as a Tablet. It is typically used for the treatment of Abortion. Other than this, Mifeprin has some other therapeutic uses, which have been discussed ahead.

Medical history of the patient along with age and gender determines the dosage of Mifeprin. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Refer to the dosage section for a detailed discussion.

Common side effects of Mifeprin include Uterine Cramps, Uterine Bleeding. Besides the aforementioned side effects, there are other adverse effects of Mifeprin as well, which are listed below. These side effects of Mifeprin are usually temporary and subside with the completion of treatment. Please speak with your doctor if these side effects worsen or persist for a longer duration.

Furthermore, you should know that effect of Mifeprin is Severe for pregnant women and Moderate for women who are breastfeeding. Further, the section on Mifeprin related warnings talks about Mifeprin's effects on the liver, heart and kidney.

Mifeprin can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Mifeprin in conditions like Bleeding, Porphyria, Diabetes. Some other conditions that can be affected by Mifeprin are listed in the contraindications section below.

Besides this, Mifeprin may also have severe interaction with some medicines. See below for a complete list.

In addition to these precautions, you may also note that Mifeprin is not safe while driving, and is is not addictive in nature.



Mifeprin Benefits & Uses

Mifeprin is used to treat the following -

Main Benefits

  • Abortion

Other Benefits

Mifeprin Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Cushing's Syndrome
  • Before or After Meal: With meal
  • Single Maximum Dose: 300 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Cushing's Syndrome
  • Before or After Meal: With meal
  • Single Maximum Dose: 300 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult(Female)
  • Disease: Abortion
  • Before or After Meal: Either
  • Single Maximum Dose: 200 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: once only
  • Course Duration: 3 days
  • Special Instructions: 24 to 48 hrs after 1st dose patient should place two 200 mcg misoprostol tablets in each cheek pouch and swallow it after 30min

Mifeprin Related Warnings

  • Is the use of Mifeprin safe for pregnant women?


    Mifeprin has many dangerous side effects in pregnant women. If you are pregnant, do not consume Mifeprin without medical advice.

    Severe
  • Is the use of Mifeprin safe during breastfeeding?


    Women who are breastfeeding can experience some moderate side effects of Mifeprin. Immediately discontinue Mifeprin if you observe any side effects. Contact your doctor, and restart using it only if your doctor considers it safe for you.

    Moderate
  • What is the effect of Mifeprin on the Kidneys?


    Mifeprin may have mild side effects on the kidneys.

    Mild
  • What is the effect of Mifeprin on the Liver?


    Mifeprin may cause harmful effects on liver. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.

    Moderate
  • What is the effect of Mifeprin on the Heart?


    Mifeprin has very mild side effects on the heart.

    Mild


Severe Interaction of Mifeprin with Other Drugs

Mifeprin should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate

Mild



Mifeprin Contraindications

If you are suffering from any of the following diseases, you should not take Mifeprin unless your doctor advises you to do so -



Frequently asked Questions about Mifeprin

  • Is this Mifeprin habit forming or addictive?


    Forming a habit of Mifeprin has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Mifeprin you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Mifeprin is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Mifeprin cannot treat any kind of mental disorder.

    No

Mifeprin Interactions with Food and Alcohol

  • Interaction between Food and Mifeprin


    There is no information on the effects of taking Mifeprin with food, because this topic has not been scientifically researched yet.

    Unknown
  • Interaction between Alcohol and Mifeprin


    Due to lack of research, there is no information about the side effects of taking Mifeprin with alcohol.

    Unknown


Frequently asked Questions about Mifeprin

Question about 5 years ago

What does Mifeprin treat?

Dr. Ayush Pandey MBBS, PG Diploma , General Physician

Mifeprin is used in combination with misoprostol to terminate early pregnancy. Early pregnancy means it has been 10 weeks or less since your last menstrual cycle began. It is also used to control hyperglycemia in people with Cushing syndrome.

Question over 4 years ago

Can I take Mifeprin and misoprostol at the same time?

Dr. Joydeep Sarkar MBBS , Internal Medicine

No, Mifeprin and misoprostol can't be taken at the same time, because it will be less effective if taken at the same time. You should always take 24 to 48 hours apart or consult your doctor regarding the exact gap between these two medicines.

Question about 5 years ago

Is Mifeprin safe to use?

Dr. Haleema Yezdani MBBS , General Physician

Yes, Mifeprin is safe to use, if taken in a prescribed amount for a specified time as advised by the doctor. However, few side effects such as diarrhea, pelvic pain, weakness, and fever may occur. 

Question over 4 years ago

Can I take Mifeprin with alcohol?

Dr. Bharat MBBS , General Physician

No harmful interactions are found between Mifeprin and alcohol, it does not reduce the effectiveness of the drug. However, alcohol can cause liver damage and dehydration in some people which may increase the severity of side effects, if taken together. So, it is better to avoid taking Mifeprin with alcohol.

Question almost 5 years ago

Does Mifeprin cause birth defects?

Dr. Madhur Anand MBBS, MS , General Surgery

Yes, If abortion has not happened after taking this Mifeprin. You are highly recommended to take a doctor's advise because this drug may cause teratogenic (birth defects of mental & physical) origin in the unborn fetus.



See all substitutes for Mifeprin


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 858-859

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 319-320

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Mifeprex® (mifepristone)



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₹387
10 Tablet in 1 Strip