Periset

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  • Contains / Salt: Ondansetron (2 mg)
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Periset Information

Periset is a prescription drug, available for use as Injection, Syrup, Tablet. It is typically used for the treatment of Nausea and Vomiting.

The optimal dosage of Periset is largely dependent on the individual's body weight, medical history, gender and age. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Refer to the dosage section for a detailed discussion.

Besides the aforementioned side effects, there are other adverse effects of Periset as well, which are listed below. Usually, these side effects of Periset go away soon, and do not persist beyond the duration of the treatment. Please speak with your doctor if these side effects worsen or persist for a longer duration.

It is also important to note that Periset has a Safe effect for pregnant women and Mild effect on lactating mothers. In addition, Periset's effects on the liver, heart and kidney are discussed below in the Periset related warnings section.

Periset is contraindicated in people with pre-existing medical conditions like Heart Disease, Calcium Deficiency, Potassium Deficiency as it can result in adverse effects. Other conditions have been mentioned below in the Periset contraindications section.

Additionally, Periset may also adversely react with other medicines. See below for a complete list.

In addition to these precautions, you may also note that Periset is not safe while driving, and is is not addictive in nature.



Periset Benefits & Uses

Periset is used to treat the following -

Periset Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
Geriatric
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
13 - 18 years (Adolescent)
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
2 - 12 years (Child)
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
Infant (1 month to 2 years)
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy. Given dose older then 6 month

Periset Related Warnings

  • Is the use of Periset safe for pregnant women?


    Pregnant women can take Periset without worrying about any side effects.

    Safe
  • Is the use of Periset safe during breastfeeding?


    Periset may have very limited harmful effects for breastfeeding women.

    Mild
  • What is the effect of Periset on the Kidneys?


    Using Periset does not have any harmful effects on kidneys.

    Safe
  • What is the effect of Periset on the Liver?


    You may experience side effects on your liver after taking Periset. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.

    Moderate
  • What is the effect of Periset on the Heart?


    There may be an adverse effect on the heart after taking Periset. If you observe any side effects on your body then stop taking this drug. Restart this medicine only if your doctor advises you to do so.

    Moderate


Severe Interaction of Periset with Other Drugs

Periset should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Periset Contraindications

If you are suffering from any of the following diseases, you should not take Periset unless your doctor advises you to do so -



Frequently asked Questions about Periset

  • Is this Periset habit forming or addictive?


    No, there is no any evidence that Periset is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Periset you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Yes, Periset is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Periset cannot treat any kind of mental disorder.

    No

Periset Interactions with Food and Alcohol

  • Interaction between Food and Periset


    Taking Periset with food does not cause any problems.

    Safe
  • Interaction between Alcohol and Periset


    Consult your doctor before consuming alcohol while taking Periset as it can have severe side effects.

    Severe


Frequently asked Questions about Periset

Question about 5 years ago

Is Periset safe for children?

Dr. R.K Singh MBBS , Diabetology

Yes, Periset is safe to be used in children from 6 months to 12 years of age. Apart from preventing nausea and vomiting related to chemotherapy and radiation, Periset can be used in this population group for managing acute gastritis. Acute gastritis presents itself as a self-limited infection with vomiting leading to dehydration and electrolyte imbalances. Always check with a child specialist and do not administer this drug yourself.

Question about 5 years ago

What is Periset?

Dr Anjum Mujawar MBBS, MBBS , Emergency Medicine

Periset is a brand name for ondansetron. It belongs to a class of compounds known as serotonin type 3 receptor antagonists. It is available in the form of tablet and injection. It is used to prevent nausea and vomiting that is caused by anti-cancer drugs, chemotherapy and radiation therapy. It is also used to prevent post-surgical nausea and vomiting. 

Question over 4 years ago

Can Periset be taken with pantoprazole?

Dr. Ramraj Meena MBBS , General Physician

Yes, Periset can be taken with pantoprazole as there are no records of any drug interaction. Pantoprazole is a proton pump inhibitor which is used for treating acidity. Acidity can be managed by avoiding eating acidic and spicy foods, avoiding smoking, and avoiding sleep within 3 hours of taking meals.

Question about 5 years ago

How to take Periset?

Dr. Saurabh Shakya MBBS , General Physician

Periset is available in form of tablet, syrup, and injection. It should be taken as per your doctor's instructions. Ideally, Periset has to be taken with food to avoid stomach upset. The initial dose is usually taken half an hour before chemotherapy, 1 to 2 hours before radiation therapy and 1 hour before a surgery. Additional doses can be suggested by the doctor as per the individual requirements.

Question over 4 years ago

Can Periset be taken with tramadol?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

No, Periset should not be ideally taken with tramadol as the action of both the drugs decreases upon concomitant use. Tramadol is an opioid medication used to treat mild to moderate pain. Take it only when a doctor has prescribed it. ​



See all substitutes for Periset


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 947-948

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 668

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran (ondansetron hydrochloride)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran® (ondansetron hydrochloride)



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