Topamate

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  • Contains / Salt: Topiramate (100 mg)
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Topamate Information

Topamate is a prescription drug, available for use as Tablet. Epilepsy are some of its major therapeutic uses. Other than this, Topamate has some other therapeutic uses, which have been discussed ahead.

Medical history of the patient along with age and gender determines the dosage of Topamate. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. This information has been provided in detail in the dosage section.

Apart from the aforementioned side effects, Topamate can also lead to other problems, which have been listed below. Normally, these side effects of Topamate are not long lasting and go away when the treatment is finished. Please speak with your doctor if these side effects worsen or persist for a longer duration.

Topamate's effect during pregnancy is Moderate and Mild while nursing. Further, the section on Topamate related warnings talks about Topamate's effects on the liver, heart and kidney.

Topamate is contraindicated in people with pre-existing medical conditions like Suicidal Tendency, Liver Disease as it can result in adverse effects. Other conditions have been mentioned below in the Topamate contraindications section.

Additionally, Topamate may also adversely react with other medicines. Refer to the list below for further details.

Along with the above-mentioned precautions, remember that taking Topamate is considered not safe while driving, and is not addictive.



Topamate Benefits & Uses

Topamate is used to treat the following -

Main Benefits

Other Benefits

Topamate Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Migraine
  • Before or After Meal: Either
  • Single Maximum Dose: 25 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: gradually increases upto 50 mg twice daily
Geriatric
  • Disease: Migraine
  • Before or After Meal: Either
  • Single Maximum Dose: 25 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: gradually increases upto 50 mg twice daily
13 - 18 years (Adolescent)
  • Disease: Migraine
  • Before or After Meal: Either
  • Single Maximum Dose: 25 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: gradually increases upto 50 mg twice daily
2 - 12 years (Child)
  • Disease: Epilepsy
  • Before or After Meal: Either
  • Single Maximum Dose: 25 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: gradually increases upto 350 mg/day


Topamate Side Effects

Based on research, the following side effects have been observed when Topamate is used -

Moderate

Mild

  • Dizziness
  • Sleepiness
  • Nausea or vomiting
  • Paresthesia
  • Diarrhoea
  • Fatigue
  • पेट दर्द
  • Tiredness

Topamate Related Warnings

  • Is the use of Topamate safe for pregnant women?


    Topamate may cause moderate side effects during pregnancy. If you feel its harmful effects, then stop taking this drug immediately, and do not take Topamate again without your doctor's advice.

    Moderate
  • Is the use of Topamate safe during breastfeeding?


    Side effects of Topamate on breastfeeding women are very mild.

    Mild
  • What is the effect of Topamate on the Kidneys?


    Topamate has very mild side effects on the kidneys.

    Mild
  • What is the effect of Topamate on the Liver?


    Very few cases of side effects of Topamate on the liver have been reported.

    Mild
  • What is the effect of Topamate on the Heart?


    Topamate is completely safe for the heart.

    Safe


Severe Interaction of Topamate with Other Drugs

Topamate should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate



Topamate Contraindications

If you are suffering from any of the following diseases, you should not take Topamate unless your doctor advises you to do so -



Frequently asked Questions about Topamate

  • Is this Topamate habit forming or addictive?


    No, you will not get addicted to Topamate.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should not drive or operate heavy machinery after taking Topamate as you may feel sleepy.

    Dangerous
  • Is it safe?


    Topamate is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Yes, Topamate is useful in treating mental disorders.

    Yes

Topamate Interactions with Food and Alcohol

  • Interaction between Food and Topamate


    Taking Topamate with food is safe.

    Safe
  • Interaction between Alcohol and Topamate


    Taking alcohol with Topamate can be dangerous.

    Severe


See all substitutes for Topamate


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1018-1019

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 420

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Topamax® (topiramate)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Trokendi XR (topiramate)



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