Trend

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  • Contains / Salt: Divalproex (500 mg)
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Trend Information

Trend is a prescription medicine that is available as a Tablet. Epilepsy, Migraine are some of its major therapeutic uses. Trend also has some secondary and off-label uses. These are listed below.

The correct dosage of Trend depends on the patient's age, gender, and medical history. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. This information has been provided in detail in the dosage section.

Some other side effects of Trend have been listed ahead. Usually, these side effects of Trend go away soon, and do not persist beyond the duration of the treatment. Consult your doctor if these side effects become worse or stay for a longer duration.

It is also important to note that Trend has a Severe effect for pregnant women and Mild effect on lactating mothers. In addition, Trend's effects on the liver, heart and kidney are discussed below in the Trend related warnings section.

Trend can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Trend in conditions like Depression, Liver Disease. Other conditions have been mentioned below in the Trend contraindications section.

Additionally, Trend may also adversely react with other medicines. A complete list of these interactions is given below.

Along with the above-mentioned precautions, remember that taking Trend is considered not safe while driving, and is not addictive.



Trend Benefits & Uses

Trend is used to treat the following -

Main Benefits

Other Benefits

Trend Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Epilepsy
  • Before or After Meal: After Meal
  • Single Maximum Dose: 5 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dose can be increased by 5 - 10 mg /kg/day every week until seizures are controlled.
13 - 18 years (Adolescent)
  • Disease: Epilepsy
  • Before or After Meal: After Meal
  • Single Maximum Dose: 5 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dose can be increased by 5 - 10 mg /kg/day every week until seizures are controlled
Geriatric
  • Disease: Mania
  • Before or After Meal: After Meal
  • Single Maximum Dose: 250 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: delayed-release tablet

Trend Related Warnings

  • Is the use of Trend safe for pregnant women?


    Trend should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.

    Severe
  • Is the use of Trend safe during breastfeeding?


    Trend may have very limited harmful effects for breastfeeding women.

    Mild
  • What is the effect of Trend on the Kidneys?


    Very few cases of side effects of Trend on kidney have been reported.

    Mild
  • What is the effect of Trend on the Liver?


    Very few cases of side effects of Trend on the liver have been reported.

    Mild
  • What is the effect of Trend on the Heart?


    You can take Trend without any fear of damage to the heart.

    Safe


Severe Interaction of Trend with Other Drugs

Trend should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate

Mild



Trend Contraindications

If you are suffering from any of the following diseases, you should not take Trend unless your doctor advises you to do so -



Frequently asked Questions about Trend

  • Is this Trend habit forming or addictive?


    No, there is no any evidence that Trend is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should not drive or operate heavy machinery after taking Trend as you may feel sleepy.

    Dangerous
  • Is it safe?


    Trend is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Yes, this Trend works for mental disorders.

    Yes

Trend Interactions with Food and Alcohol

  • Interaction between Food and Trend


    Taking Trend with food is safe.

    Safe
  • Interaction between Alcohol and Trend


    Consuming Trend with alcohol can have many serious effects on your body.

    Severe


Frequently asked Questions about Trend

Question almost 5 years ago

Does Trend cause stomach upset?

Dr. Roshni Poonja MBBS , General Physician, Internal Medicine

Yes, Trend can cause stomach upset. Please inform your doctor if you are experiencing stomach upset after taking this medicine.

Question almost 5 years ago

Does Trend cause weight fluctuations?

Dr. Madhur Anand MBBS, MS , General Surgery

Yes, Trend may cause weight fluctuations (weight gain or loss). It is a rare side effect of this drug. If you are experiencing unusual weight fluctuations after taking this drug, then you are advised to discuss it with your doctor without further delay.

Question over 4 years ago

Can Trend cause low blood pressure?

Dr. Madhur Anand MBBS, MS , General Surgery

Yes, Trend causes low blood pressure (hypotension) in the patients who are taking it. However, the exact cause behind this is unknown. If you are experiencing dizziness or lightheadedness which is a symptom of low blood pressure after taking this drug, then please consult with your doctor.

Question about 5 years ago

Can I take Trend with ibuprofen?

Dr. Vipin Khadse MBBS , General Physician

Yes, Trend can be taken with ibuprofen. No harmful interaction has been reported between them. However, it doesn't mean that no interaction exists between them. Always consult your doctor before taking these two medicines at the same time.

Question over 5 years ago

What is Trend?

Dr. Saurabh Shakya MBBS , General Physician

Trend is a brand name for divalproex. It is a prescription drug that belongs to the class of drug called anti-epileptic drug, also known as an anticonvulsant and anti-seizure medication. It is used in the treatment of epilepsy (seizure). Trend is also used to treat mania associated with bipolar disorder and to prevent episodes of migraine headache. 



See all substitutes for Trend


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 418

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Depakote (divalproex sodium)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Depakote Er (divalproex sodium)



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