Unitrexate

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1 Injection in 1 Packet Out of Stock
₹ 48
1 INJECTION 1 Packet ₹ 48
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  • Contains / Salt: Methotrexate (15 mg)
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Unitrexate Information

Unitrexate is a prescription medicine that is available as a Injection. Non-Hodgkin Lymphoma, Lymphoma are some of its major therapeutic uses. Other than this, Unitrexate has some other therapeutic uses, which have been discussed ahead.

Medical history of the patient along with age and gender determines the dosage of Unitrexate. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Refer to the dosage section for a detailed discussion.

The side effects typically associated with Unitrexate include Abdominal Pain. Besides the aforementioned side effects, there are other adverse effects of Unitrexate as well, which are listed below. These side effects of Unitrexate are usually temporary and subside with the completion of treatment. However, if these continue for a longer time, consult your doctor right away.

Unitrexate's effect during pregnancy is Severe and Severe while nursing. Further, the section on Unitrexate related warnings talks about Unitrexate's effects on the liver, heart and kidney.

Unitrexate is not recommended if you suffer from certain medical conditions as it can have adverse effects. Infections, Liver Disease, Anemia are examples of such conditions. Other contraindications of Unitrexate have been discussed in the sections ahead.

Additionally, Unitrexate may also adversely react with other medicines. See below for a complete list.

In addition to these precautions, you may also note that Unitrexate is safe while driving, and is is addictive in nature.



Unitrexate Benefits & Uses

Unitrexate is used to treat the following -

Other Benefits

Unitrexate Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 15 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 15 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 12 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 12 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Infant (1 month to 2 years)
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 6 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult(Female)
  • Disease: Breast Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 60 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor


Unitrexate Side Effects

Based on research, the following side effects have been observed when Unitrexate is used -

Moderate

  • Stomatitis (Inflammation of the mouth)

Mild

Common

  • पेट दर्द

Unitrexate Related Warnings

  • Is the use of Unitrexate safe for pregnant women?


    Pregnant women may get severe side effects after taking Unitrexate. If you are pregnant, do not take Unitrexate without a doctor's advice.

    Severe
  • Is the use of Unitrexate safe during breastfeeding?


    Women who are breastfeeding may experience severe harmful effects after taking Unitrexate. It should only be taken after medical advice.

    Severe
  • What is the effect of Unitrexate on the Kidneys?


    Unitrexate can have moderate side effects on the kidney. If you notice any harmful effects, stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Unitrexate on the Liver?


    Unitrexate may cause harmful effects on liver. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.

    Moderate
  • What is the effect of Unitrexate on the Heart?


    Unitrexate may have mild side effects on the heart. Most people will never see any effect on the heart.

    Mild


Severe Interaction of Unitrexate with Other Drugs

Unitrexate should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Unitrexate Contraindications

If you are suffering from any of the following diseases, you should not take Unitrexate unless your doctor advises you to do so -



Frequently asked Questions about Unitrexate

  • Is this Unitrexate habit forming or addictive?


    Forming a habit of Unitrexate has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can operate a vehicle or heavy machinery after taking Unitrexate since it does not cause drowsiness.

    Safe
  • Is it safe?


    Yes, but consume Unitrexate only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Unitrexate cannot treat any kind of mental disorder.

    No

Unitrexate Interactions with Food and Alcohol

  • Interaction between Food and Unitrexate


    Due to a lack of research, nothing can be said about the consequences of taking Unitrexate together with food.

    Unknown
  • Interaction between Alcohol and Unitrexate


    Side effects of drinking alcohol and taking Unitrexate at the same time are rare and minor. However, if you face any side effects, talk to your doctor immediately.

    Mild


Frequently asked Questions about Unitrexate

Question about 5 years ago

What is Unitrexate?

Dr. R.K Singh MBBS , Diabetology

Unitrexate is a brand name of methotrexate and it comes in the form of tablet and injection. It is a chemotherapy drug that belongs to the class of drug known as antimetabolites and it also has immunosuppressant properties. It is a prescription drug which is used for the treatment of various types of cancers such as breast cancer, bone cancer, head, and neck cancer. It is also used in the treatment of autoimmune and inflammatory diseases such as psoriasis, rheumatoid arthritis, and Crohn's disease.

Question over 4 years ago

Can Unitrexate cause hair loss?

Dr. Suhas Bhargav MBBS , General Physician

Yes, Unitrexate causes hair loss (alopecia). It is a known side effect of this drug. This side effect is reversible in nature and it is resolved after the discontinuation of this drug.

Question almost 5 years ago

Is Unitrexate safe to use?

Aakash Shah MBBS, MBBS , General Physician

Yes, Unitrexate is safe to use, if taken in prescribed amount and duration as advised by the doctor. However, certain side effects have been associated with this drug such as gingivitis (inflammation of gum), mouth ulcers, and diarrhoea. If you experience above-mentioned side effects after taking this medicine then inform your doctor and follow his/her instructions.

Question over 4 years ago

Does Unitrexate raise blood sugar?

Dr. Abhijit MBBS , General Physician

No, Unitrexate does not raise blood sugar levels (hyperglycemia). It has not been reported by the patients who are taking it. However, if you are experiencing increased thirst, trouble concentrating, and frequent urination which are symptoms of increased blood sugar levels (hyperglycemia) then do discuss with your doctor.

Question almost 4 years ago

Can I take Unitrexate with clindamycin?

Dr. Saikat Mukherjee MBBS , General Physician

Yes, Unitrexate can be taken with clindamycin. No harmful drug interaction has been reported between them. It is safe to take Unitrexate along with clindamycin. 



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This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Methotrexate

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 862-863

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 832-834

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