Zondel

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Zondel Information

Zondel is a commercial drug that is prescribed in the form of Tablet, Syrup. It is typically used for the treatment of Nausea and Vomiting.

The correct dosage of Zondel depends on the patient's age, gender, and medical history. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Refer to the dosage section for a detailed discussion.

While these are the most often observed Zondel side effects, there are can be others also. These have been listed below. These side effects of Zondel are usually temporary and subside with the completion of treatment. If, however, they worsen or do not go away, please speak with your physician.

Zondel's effect during pregnancy is Safe and Mild while nursing. It is important to know if Zondel has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Zondel related warnings section.

Zondel can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Zondel in conditions like Heart Disease, Calcium Deficiency, Potassium Deficiency. Other contraindications of Zondel have been discussed in the sections ahead.

Besides this, Zondel may also have severe interaction with some medicines. Refer to the list below for further details.

In addition to the above precautions for Zondel, it is important to know that it is not safe while driving, and is not habit-forming.



Zondel Benefits & Uses

Zondel is used to treat the following -

Zondel Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Nausea and Vomiting
  • Before or After Meal: Either
  • Single Maximum Dose: 8 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 2 days
  • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy
Geriatric
  • Disease: Nausea and Vomiting
  • Before or After Meal: Either
  • Single Maximum Dose: 8 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 2 days
  • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy
13 - 18 years (Adolescent)
  • Disease: Nausea and Vomiting
  • Before or After Meal: Either
  • Single Maximum Dose: 8 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 5 days
  • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy
2 - 12 years (Child)
  • Disease: Nausea and Vomiting
  • Before or After Meal: Either
  • Single Maximum Dose: 4 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: 5 days
  • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy

Zondel Related Warnings

  • Is the use of Zondel safe for pregnant women?


    Pregnant women can take Zondel safely.

    Safe
  • Is the use of Zondel safe during breastfeeding?


    Zondel may have very limited harmful effects for breastfeeding women.

    Mild
  • What is the effect of Zondel on the Kidneys?


    Zondel is not harmful for kidneys.

    Safe
  • What is the effect of Zondel on the Liver?


    There may be an adverse effect on the liver after taking Zondel. If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.

    Moderate
  • What is the effect of Zondel on the Heart?


    The heart can be affected by Zondel. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart the medicine only after medical advice.

    Moderate


Severe Interaction of Zondel with Other Drugs

Zondel should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Zondel Contraindications

If you are suffering from any of the following diseases, you should not take Zondel unless your doctor advises you to do so -



Frequently asked Questions about Zondel

  • Is this Zondel habit forming or addictive?


    No, there is no any evidence that Zondel is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Zondel you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Zondel is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Zondel is not used to treat mental disorders.

    No

Zondel Interactions with Food and Alcohol

  • Interaction between Food and Zondel


    Taking Zondel with food does not harm your health.

    Safe
  • Interaction between Alcohol and Zondel


    Consumption of alcohol and Zondel together may have severe effects on your health.

    Severe


Frequently asked Questions about Zondel

Question about 5 years ago

Is Zondel an antibiotic?

Dr. Yogesh Kumar MBBS , General Physician

No, Zondel is not an antibiotic. It is an anti-emetic medication which is used to prevent vomiting associated with chemotherapy and radiation therapy. 

Question almost 5 years ago

Is it safe to take Zondel?

Dr. Vedprakash Verma MBBS, MD , Cardiology

Yes, it is safe to take Zondel for as long as it is prescribed by your doctor. Do not take more or less of Zondel, more frequently or less frequently. It is important to follow the recommendations of your doctor completely. 

Question almost 5 years ago

Can Zondel be taken with tramadol?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

No, Zondel should not be ideally taken with tramadol as the action of both the drugs decreases upon concomitant use. Tramadol is an opioid medication used to treat mild to moderate pain. Take it only when a doctor has prescribed it. ​

Question over 4 years ago

Why Zondel is prescribed post surgery?

Dr. Yogesh Kumar MBBS , General Physician

Yes, Zondel is usually administered before and after surgery for treating post-anesthesia shivering (PAS) and nausea. PAS is a condition in which tremors of head, neck, trunk, shoulder, and extremities. It greatly reduces the quality of life of a patient since it causes discomfort and increases pain. It disturbs surgical care and increases the stress on cardiopulmonary functions. Hence as a precautionary measure, this medicine is administered to prevent unpleasant anesthetic effects.

Question about 5 years ago

How does Zondel work?

Dr. Uday Nath Sahoo MBBS , Internal Medicine

Zondel belongs to a class of compounds known as 5 -HT3 receptor antagonists. It blocks the action of serotonin completely at the 5-HT3 receptor sites present in our brain (vomiting centre) which provides relief to the patient from nausea and vomiting.



See all substitutes for Zondel


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 947-948

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 668

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran (ondansetron hydrochloride)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran® (ondansetron hydrochloride)

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