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What is Paget’s disease?

Paget’s disease is a medical condition characterized by faulty bone formation and bone deformities. The new bones formed are usually weak and brittle. After osteoporosis, it is the second most common bone metabolism disorder. When these bones fracture, they take much longer to heal. This is due to defects in the bone renewal process. It is most commonly seen in the legs, skull, pelvis and spine.

What are its main signs and symptoms?

The common signs and symptoms are:

What are the main causes?

The exact cause is still unknown. However, it is believed that the factors mentioned below might cause it:

  • Abnormal functioning of the osteoclasts (cells that absorb the old bone) and osteoblasts (cells that form the new bone).
  • Some kind of infection in bone cells caused by the rubeola virus.
  • Heredity is another factor as the condition tends to be found running in families.
  • The age factor is also important as it is rarely seen in persons under 40 years.

How is it diagnosed and treated?

It can be diagnosed by various methods such as:

  • Physical examination
    It helps in finding any irregularities in the bone shape and size.
  • Blood tests
    Presence of phosphatase in blood as it is an indicator of Paget’s disease.
  • X-ray  
    It confirms the disease and also helps in detecting fractures and low bone density.

Though full recovery is impossible, treatments can slow down the bone turnover and control the impact of the disease. The treatments are:

  • If there are severe bone fractures or damage or deformation of bones due to Paget’s disease, then surgery is the treatment of choice.
  • Anti-inflammatory drugs.
  • Analgesics (pain relievers).
  • Bisphosphonate drugs that help in blocking the action of osteoclasts.
  1. Medicines for Paget's Disease

Medicines for Paget's Disease

Medicines listed below are available for Paget's Disease. Please note that you should not take any medicines without doctor consultation. Taking any medicine without doctor's consultation can cause serious problems.

Medicine NamePack SizePrice (Rs.)
ActonelActonel 35 Mg Tablet2310.0
FossicalFossical 35 Mg Tablet94.0
GemfosGemfos 150 Mg Tablet199.0
OsedrateOsedrate 35 Mg Tablet155.0
RisoweekRisoweek 35 Mg Tablet156.0
RisofosRisofos 150 Mg Tablet196.0
AlendrateAlendrate 70 Mg Tablet75.0
AlenfosAlenfos 10 Mg Tablet60.0
AlenostAlenost 10 Mg Tablet49.0
BifosaBifosa 70 Mg Tablet134.0
Newbona JellyNewbona Jelly 70 Mg Sachet59.0
OsteofosOsteofos 35 Mg Tablet88.0
RestofosRestofos 10 Mg Tablet62.0
ZophostZophost 10 Mg Tablet40.0
BlaztereBlaztere 4 Mg Injection3212.0
NatzoldNatzold Infusion2990.0
NewbonaNewbona Capsule109.0
RokfosRokfos 5 Mg Infusion2950.0
VacosteoVacosteo 5 Mg Infusion2650.0
ZoboneZobone 5 Mg Infusion2697.95
ZoldonatZoldonat 4 Mg Injection2990.0
ZolephosZolephos 5 Mg Infusion3000.0
ZyclastinZyclastin 4 Mg Injection2949.52
ZyfossZyfoss 4 Mg Injection2933.0
AclastaAclasta 5 Mg Infusion23456.7
DronicadDronicad 4 Mg Injection2500.0
GemdronicGemdronic 5 Mg Infusion2380.95
LedronzolLedronzol 4 Mg Injection1371.42
WellboneWellbone 5 Mg Infusion2999.0
XolnicXolnic 4 Mg Injection1500.0
ZolastaZolasta 4 Mg Injection416.66
ZoldaroZoldaro 4 Mg Injection1540.0
ZoldriaZoldria 4 Mg Injection2800.0
ZoledronZoledron 4 Mg Injection1357.47
ZolestoZolesto 4 Mg Injection2500.0
ZoletrustZoletrust 4 Mg Injection1519.05
ZolfracZolfrac 5 Mg Injection3500.0
ZolonZolon 4 Mg Injection918.75
ZometaZometa 4 Mg Injection18110.7
ZorrentZorrent 4 Mg Injection937.5
ZyronaZyrona 5 Mg Infusion6500.0
BiodronateBiodronate 30 Mg Injection1168.12
AredronetAredronet 30 Mg Injection1830.4
PamidriaPamidria 30 Mg Injection2306.0
BiocalcinBiocalcin 100 Iu Injection184.42
KalnaseKalnase Nasal Spray950.0
UnicalcinUnicalcin 100 Iu Injection185.0
Rockbon CRockbon C 100 Iu Spray1520.0
CalsprayCalspray 100 Iu Spray1310.0
DisonateDisonate 200 Mg Tablet237.5
EtifemEtifem 200 Mg Tablet105.0
FosavanceFosavance 70 Mg/5600 Iu Tablet499.0
OstonatOstonat Kit175.0
Alenost DAlenost D Tablet171.0
T ScoreT Score Tablet166.67
GemcalGemcal Kit160.5

Do you or anyone in your family have this disease? Please do a survey and help others

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