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What is soft tissue sarcoma?

Soft tissue sarcoma is an umbrella term used for a group of rare cancers that affect the connective tissues of the body. There are multiple types of soft tissue sarcomas depending on the location and the type of soft tissue affected.

The connective tissues of the body include blood vessels, muscles, fats, tendons, ligaments, deep skin tissues, and nerves.

These sarcomas (cancerous tumours) can develop in the arms, legs, torso, and the head and neck region.

What are its main signs and symptoms?

  • Symptoms tend to have a gradual onset, hence, a patient may be asymptomatic in the early stage of the disease.
  • As the size of the tumour grows, it may produce pain due to impinging of an underlying structure.
  • If the sarcoma is in the chest region, near the lungs, then the patient can have difficulty in breathing.
  • Abdominal soft tissue sarcomas may present with stomach pain or cramps.
  • Vomiting blood, loss of appetite, weakness, and fever are other common signs of soft tissue sarcomas.

What are the main causes?

  • Sarcomas do not have a specific cause.
  • They may often have a genetic cause or are linked to a family history of sarcomas.
  • A person who is undergoing radiation therapy for some other kind of cancer can also develop sarcomas due to adverse effects of radiotherapy.
  • Exposure to chemicals like arsenic and herbicides increases the risk of developing soft tissue sarcomas.

How is it diagnosed and treated?

  • Common investigations that are used to detect sarcomas include computed tomography (CT), X-ray, magnetic resonance imaging (MRI), and ultrasound.
  • A biopsy, in which a tissue sample of the tumour is examined, can help to confirm the malignant (cancerous) nature of the tumour.


  • Treatment of malignant tumours comprises of surgical removal of the tumour. In surgery, a part of the surrounding healthy tissue may also be removed.
  • Sometimes, if the sarcoma is in the limbs, surgery is avoided to overcome the risk of amputation.
  • Radiation therapy is also used to shrink the size of the tumour before surgically removing it.
  • Radiation is known to have side effects like joint problems, swellings, etc.
  • Chemotherapy in the form of intravenous medicines or pills may also be used for the treatment of a sarcoma.
  • The final treatment plan depends on the type of sarcoma, the size of the tumour, and the overall condition of the patient.
  1. Medicines for Soft Tissue Sarcoma

Medicines for Soft Tissue Sarcoma

Medicines listed below are available for Soft Tissue Sarcoma. Please note that you should not take any medicines without doctor consultation. Taking any medicine without doctor's consultation can cause serious problems.

Medicine NamePack SizePrice (Rs.)
VotrientVotrient 200 Mg Tablet5800
YondelisYondelis 1 Mg Injection97188
ActinocinActinocin 0.5 Mg Injection329
CosmegenCosmegen 500 Mcg Injection72
DacilonDacilon 0.5 Mg Injection356
DoxiglanDoxiglan 50 Mg Injection799
AdriamycinAdriamycin RTU 10 mg Injection139
AdriblastinaAdriblastina Injection1047
Adronex RdAdronex Rd 10 Mg Injection148
AdrosalAdrosal 10 Mg Injection156
CadriaCadria 10 Mg Injection132
CardiaroneCardiarone 100 Mg Tablet52
DoxilydDoxilyd 10 Mg Injection95
DoxohopeDoxohope 20 Mg Injection6530
DoxorexDoxorex 10 Mg Injection103
DoxorubicinDoxorubicin 10 Mg Injection92
Doxorubicin (Plain)Doxorubicin 10 Mg Injection160
DoxorubinDoxorubin 10 Mg Injection104
DoxotarDoxotar 10 Mg Injection228

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  1. J J Lewis, D Leung, J M Woodruff, M F Brennan. Retroperitoneal soft-tissue sarcoma: analysis of 500 patients treated and followed at a single institution. Ann Surg. 1998 Sep; 228(3): 355–365. PMID: 9742918
  2. Hoefkens F et al. Soft tissue sarcoma of the extremities: pending questions on surgery and radiotherapy. Radiat Oncol. 2016 Oct 12;11(1):136. PMID: 27733179
  3. National Cancer Institute [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; Soft Tissue Sarcoma—Health Professional Version
  4. National Center for Advancing and Translational Sciences. Soft tissue sarcoma. Genetic and Rare Diseases Information Center
  5. PDQ Adult Treatment Editorial Board. Adult Soft Tissue Sarcoma Treatment (PDQ®): Patient Version. 2019 May 21. In: PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-.
  6. MedlinePlus Medical Encyclopedia: US National Library of Medicine; Soft Tissue Sarcoma
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