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What is Wilms tumour?

Wilms tumour is an embryonal type of renal or kidney cancer. It is the most common type of solid malignant neoplasm (cancerous tumour) in children. This condition was first described under a different name by Dr Max Wilms, a surgeon, and was initially known as congenital sarcoma of the kidney.

What are its main signs and symptoms?

The tumour is almost always found before the child reaches 10 years of age. Common symptoms of Wilms tumour include:

  • Palpable abdominal mass
  • Abdominal pain
  • Loss of appetite
  • Nausea
  • Vomiting
  • Haematuria (presence of blood in urine)
  • Hepatomegaly (enlarged liver)
  • Ascites (accumulation of fluid in the abdomen)
  • Congestive heart failure
  • Increased blood pressure
  • Dysmorphism (abnormal body structure)
  • Pallor

What are the main causes?

Wilms tumour is a rare disease and genetic factors play a vital role. Substantial genetics and molecular studies have contributed to an understanding of the pathogenesis of Wilms tumour. Changes in chromosome 11 have been associated with Wilms tumour.

How is it diagnosed and treated?

Wilms tumour is diagnosed by:

  • Presence of upper abdominal swelling
  • History and family history
  • Ultrasonography of the abdomen and pelvis
  • Hypoglycaemia (low blood sugar) in infants
  • Computed tomography (CT) scan
  • Complete blood count (CBC)
  • Renal (kidney) function test
  • Urinalysis
  • Liver function tests

Treatment of Wilms tumour includes surgery, chemotherapy, and radiotherapy. The role of surgery is critical, as there may be chances of tumour rupture. Transperitoneal radical removal, a type of surgery where the kidney is removed by opening the abdomen, of the kidney is the most preferred operative procedure for unilateral renal tumour. Partial removal of the kidney and excision is also considered in many cases. Recovery happens rapidly once removal is done. Dialysis might be needed going ahead to prevent complications related to overload on one kidney.

 

  1. Medicines for Wilms Tumor

Medicines for Wilms Tumor

Medicines listed below are available for Wilms Tumor. Please note that you should not take any medicines without doctor consultation. Taking any medicine without doctor's consultation can cause serious problems.

Medicine NamePack SizePrice (Rs.)
AdriamycinAdriamycin 10 Mg Injection221.61
AdriblastinaAdriblastina Injection1309.52
Adronex RdAdronex Rd 10 Mg Injection185.71
AdrosalAdrosal 10 Mg Injection196.43
CadriaCadria 10 Mg Injection166.66
CardiaroneCardiarone 100 Mg Tablet65.47
DoxilydDoxilyd 10 Mg Injection119.04
DoxohopeDoxohope 20 Mg Injection8163.26
DoxorexDoxorex 10 Mg Injection321.75
Doxorubicin (Dr. Reddys)Doxorubicin 10 Mg Injection116.66
DoxorubicinDoxorubicin 10 Mg Injection200.0
DoxorubinDoxorubin 10 Mg Injection130.95
DoxotarDoxotar 10 Mg Injection285.0
DoxoteroDoxotero 10 Mg Injection165.0
DoxulipDoxulip 20 Mg Injection7890.0
DoxutecDoxutec 10 Mg Injection170.0
DuxocinDuxocin 10 Mg Injection190.94
LyphidoxLyphidox 10 Mg Injection198.91
MetodoxMetodox 10 Mg Injection63.09
OncodriaOncodria 10 Mg Injection199.64
PiglitPiglit 2 Mg Injection6184.52
ZodoxZodox 10 Mg Injection196.19
ZubidoxZubidox 10 Mg Injection200.0
BiocristinBiocristin 1 Mg Injection52.63
Biocristin AqBiocristin Aq 1 Mg Injection48.38
IvinIvin 1 Mg Injection105.31
OnvincOnvinc 1 Mg Injection48.07
UnicristinUnicristin 1 Mg Injection55.0
VinlonVinlon 1 Mg Injection50.79
VinstinVinstin 1 Mg Injection226.19
AlcristAlcrist 1 Mg Injection51.93
CytocristinCytocristin 1 Mg Injection56.89
Oncocristin AqOncocristin Aq 1 Mg Injection61.0
ParacristineParacristine Injection69.64
VcadVcad 1 Mg Injection89.79
ActinocinActinocin 0.5 Mg Injection412.5
CosmegenCosmegen 500 Mcg Injection90.58
DacilonDacilon 0.5 Mg Injection445.0
AdrimAdrim 10 Mg Injection214.28
DoxiglanDoxiglan 50 Mg Injection999.0

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