Methofast

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1 Injection in 1 Packet Out of Stock
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1 INJECTION 1 Packet ₹ 61
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  • Contains / Salt: Methotrexate (15 mg)
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Methofast Information

Methofast is a prescription drug, available for use as Injection. It is primarily used for the treatment of Non-Hodgkin Lymphoma, Lymphoma. Secondary and off-label uses of Methofast have also been mentioned below.

The optimal dosage of Methofast is largely dependent on the individual's body weight, medical history, gender and age. Individual symptoms and route of administration also determines the right dosage. For detailed information on this, read through the dosage section.

Methofast also has some side effects, the most common being Abdominal Pain. Besides the aforementioned side effects, there are other adverse effects of Methofast as well, which are listed below. Such side effects of Methofast normally do not last long and go away once the treatment is completed. Consult your doctor if these side effects become worse or stay for a longer duration.

Furthermore, you should know that effect of Methofast is Severe for pregnant women and Severe for women who are breastfeeding. Further, the section on Methofast related warnings talks about Methofast's effects on the liver, heart and kidney.

Individuals suffering from medical conditions like Infections, Liver Disease, Anemia must refrain from the use of Methofast since this can cause severe adverse effects. The section on Methofast contraindications lists all such conditions.

Additionally, Methofast may also adversely react with other medicines. See below for a complete list.

In addition to the above precautions for Methofast, it is important to know that it is safe while driving, and is habit-forming.



Methofast Benefits & Uses

Methofast is used to treat the following -

Other Benefits

Methofast Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 15 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 15 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 12 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 12 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Infant (1 month to 2 years)
  • Disease: B-Cell Acute Lymphoblastic Leukemia
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 6 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult(Female)
  • Disease: Breast Cancer
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 60 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor


Methofast Side Effects

Based on research, the following side effects have been observed when Methofast is used -

Moderate

  • Stomatitis (Inflammation of the mouth)

Mild

Common

  • पेट दर्द

Methofast Related Warnings

  • Is the use of Methofast safe for pregnant women?


    Methofast has many dangerous side effects in pregnant women. If you are pregnant, do not consume Methofast without medical advice.

    Severe
  • Is the use of Methofast safe during breastfeeding?


    Women who are breastfeeding may experience severe harmful effects after taking Methofast. It should only be taken after medical advice.

    Severe
  • What is the effect of Methofast on the Kidneys?


    Kidney can be affected by Methofast. If you experience any unwanted effects of this drug, stop taking it. You should take it again only after medical advice.

    Moderate
  • What is the effect of Methofast on the Liver?


    You may experience side effects on your liver after taking Methofast. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.

    Moderate
  • What is the effect of Methofast on the Heart?


    Methofast is rarely harmful for the heart.

    Mild


Severe Interaction of Methofast with Other Drugs

Methofast should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Methofast Contraindications

If you are suffering from any of the following diseases, you should not take Methofast unless your doctor advises you to do so -



Frequently asked Questions about Methofast

  • Is this Methofast habit forming or addictive?


    Methofast does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Methofast will not make you feel sleepy or drowsy. So you drive or operate machinery safely.

    Safe
  • Is it safe?


    Yes, but consume Methofast only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Methofast is not used to treat mental disorders.

    No

Methofast Interactions with Food and Alcohol

  • Interaction between Food and Methofast


    There is no information on the effects of taking Methofast with food, because this topic has not been scientifically researched yet.

    Unknown
  • Interaction between Alcohol and Methofast


    Side effects of drinking alcohol and taking Methofast at the same time are rare and minor. However, if you face any side effects, talk to your doctor immediately.

    Mild


Frequently asked Questions about Methofast

Question about 5 years ago

What is Methofast?

Dr. R.K Singh MBBS , Diabetology

Methofast is a brand name of methotrexate and it comes in the form of tablet and injection. It is a chemotherapy drug that belongs to the class of drug known as antimetabolites and it also has immunosuppressant properties. It is a prescription drug which is used for the treatment of various types of cancers such as breast cancer, bone cancer, head, and neck cancer. It is also used in the treatment of autoimmune and inflammatory diseases such as psoriasis, rheumatoid arthritis, and Crohn's disease.

Question almost 5 years ago

Can I take Methofast without consulting a doctor?

Dr. Rahul Poddar MBBS, DNB, MBBS, DNB , General Surgery

No, Methofast is a prescription drug so do not take it without consulting a doctor. It can be harmful for the patient to take this medicine without a doctor's recommendation because it can cause unpleasant side effects. Hence, the patient should seek doctors advice before taking this medication by himself or herself.

Question over 4 years ago

Can Methofast raise blood pressure?

Dr. Gaurav MBBS , General Physician

No, Methofast does not raise blood pressure (hypertension). It has not been reported by the patients who are taking this drug.

Question about 5 years ago

How to take Methofast?

Dr. Kuldeep Meena MBBS, MD , Cardiology, Neurology, Pediatrics, Dermatology, Pulmonology, Nephrology, General Physician, Other, Infectious Disease, Emergency Medicine, Allergy and Immunology, Internal Medicine, Multispeciality

The dosage of this drug may vary depending on the diagnosis and the patient's medical condition. Take Methofast as advised by your doctor. Ideally, oral Methofast has to be taken empty stomach because the presence of food might affect the absorption of this drug from the stomach. Precautions must be taken in patients with bone marrow depression, and improper liver or kidney function.

Question almost 5 years ago

Is Methofast safe to use?

Dr. , General Physician

Yes, Methofast is safe to use, if taken in prescribed amount and duration as advised by the doctor. However, certain side effects have been associated with this drug such as gingivitis (inflammation of gum), mouth ulcers, and diarrhoea. If you experience above-mentioned side effects after taking this medicine then inform your doctor and follow his/her instructions.



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This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Methotrexate

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 862-863

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 832-834



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