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Niofine, a prescription drug, is manufactured in various forms such as Tablet, Powder. It is primarily used for the treatment of Fungal Infections, Nail Fungus. Secondary and off-label uses of Niofine have also been mentioned below.
The right dosage of Niofine depends on the age, gender, and medical history of the patient. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Refer to the dosage section for a detailed discussion.
Niofine also has some side effects, the most common being Abdominal Pain, Headache, Flatulence. Some other side effects of Niofine have been listed ahead. Normally, these side effects of Niofine are not long lasting and go away when the treatment is finished. Please speak with your doctor if these side effects worsen or persist for a longer duration.
Furthermore, you should know that effect of Niofine is Safe for pregnant women and Severe for women who are breastfeeding. Warnings related to Niofine's effects on the liver, heart and kidney, if any, have been listed below.
Some other conditions that can be affected by Niofine are listed in the contraindications section below.
Drug interactions for Niofine have been reported in the medical literature. See below for a complete list.
You should also be aware that Niofine is not safe while driving, and is not addiction.
Niofine is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
13 - 18 years (Adolescent) |
|
2 - 12 years (Child) |
|
Is the use of Niofine safe for pregnant women?
Pregnant women can take Niofine without worrying about any side effects.
Is the use of Niofine safe during breastfeeding?
Niofine may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.
What is the effect of Niofine on the Kidneys?
Niofine can have moderate side effects on the kidney. If you notice any harmful effects, stop taking this drug right away. Consult your doctor before using this medicine again.
What is the effect of Niofine on the Liver?
Niofine can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.
What is the effect of Niofine on the Heart?
Niofine is completely safe for the heart.
Niofine should not be taken with following medicines due to severe side effects it may cause to patients -
Moderate
Mild
If you are suffering from any of the following diseases, you should not take Niofine unless your doctor advises you to do so -
Is this Niofine habit forming or addictive?
No, you will not get addicted to Niofine.
Is it safe to drive or operate heavy machinery when consuming?
No, you should not drive or operate heavy machinery after taking Niofine as you may feel sleepy.
Is it safe?
Yes, but take Niofine only as per medical advice.
Is it able to treat mental disorders?
No, the use of Niofine in mental disorders is not effective.
Interaction between Food and Niofine
You can take Niofine with food.
Interaction between Alcohol and Niofine
No research has been done on this till date. Therefore, it is not known what the effect of taking Niofine with alcohol will be.
Niofine and amoxicillin can be taken together, as there are no reported harmful interactions between them. However, it doesn't mean that no interaction could exist. Please take if prescribed by a doctor only do not self-medicate.
No, Niofine does not affect the sperm count in males, however, if you're experiencing any reproductive disorder after taking this medication, please inform your doctor.
Yes, Niofine can sometimes affect the liver by increasing the secretion of liver enzymes which can damage the liver cells. Rare cases of serious hepatotoxicity (liver damage), including liver failure have been reported. Hence a routine liver function test should be conducted when taking this drug for a long time.
Niofine works by preventing the fungal infection to grow further. They inhibit cytochrome P450 enzyme 14- demethylase and block ergosterol synthesis. This action results in the destruction of cell membranes of the pathogen by limiting the growth of the fungus. Hence, in this way, it kills fungus and protect us from infection.
Niofine can be taken orally and applied topically. An oral form such as tablet should be taken with or without food and avoid caffeine intake while on medicine. Duration and dose of the course will vary according to the severity of the antifungal infection. The topical form of medicine should be applied to the affected area twice daily or as adviced by a doctor, do not apply more or less as recommended by healthcare practitioners.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Lamisil (terbinafine hydrochloride)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 795-796
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 174-177