Ondanbic

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Ondanbic Information

Ondanbic is a commercial drug that is prescribed in the form of Syrup, Tablet. It is typically used for the treatment of Nausea and Vomiting.

Medical history of the patient along with age and gender determines the dosage of Ondanbic. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Detailed information has been provided in the dosage section.

While these are the most often observed Ondanbic side effects, there are can be others also. These have been listed below. Such side effects of Ondanbic normally do not last long and go away once the treatment is completed. If, however, they worsen or do not go away, please speak with your physician.

In addition, Ondanbic's effect is Safe during pregnancy and Mild for lactating mothers. Further, the section on Ondanbic related warnings talks about Ondanbic's effects on the liver, heart and kidney.

Ondanbic is not recommended if you suffer from certain medical conditions as it can have adverse effects. Heart Disease, Calcium Deficiency, Potassium Deficiency are examples of such conditions. The section on Ondanbic contraindications lists all such conditions.

Drug interactions for Ondanbic have been reported in the medical literature. See below for a complete list.

Along with the above-mentioned precautions, remember that taking Ondanbic is considered not safe while driving, and is not addictive.



Ondanbic Benefits & Uses

Ondanbic is used to treat the following -

Ondanbic Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Nausea and Vomiting
  • Before or After Meal: Either
  • Single Maximum Dose: 8 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 2 days
  • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy
Geriatric
  • Disease: Nausea and Vomiting
  • Before or After Meal: Either
  • Single Maximum Dose: 8 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 2 days
  • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy
13 - 18 years (Adolescent)
  • Disease: Nausea and Vomiting
  • Before or After Meal: Either
  • Single Maximum Dose: 8 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 5 days
  • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy
2 - 12 years (Child)
  • Disease: Nausea and Vomiting
  • Before or After Meal: Either
  • Single Maximum Dose: 4 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: 5 days
  • Special Instructions: Give first dose 30 minutes before the start of emetogenic chemotherapy

Ondanbic Related Warnings

  • Is the use of Ondanbic safe for pregnant women?


    Pregnant women can take Ondanbic without worrying about any side effects.

    Safe
  • Is the use of Ondanbic safe during breastfeeding?


    Side effects of Ondanbic for breastfeeding are little to none, so you can take it without doctor's advice.

    Mild
  • What is the effect of Ondanbic on the Kidneys?


    Ondanbic does not damage the kidneys.

    Safe
  • What is the effect of Ondanbic on the Liver?


    Ondanbic can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Ondanbic on the Heart?


    The heart can be affected by Ondanbic. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart the medicine only after medical advice.

    Moderate


Severe Interaction of Ondanbic with Other Drugs

Ondanbic should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Ondanbic Contraindications

If you are suffering from any of the following diseases, you should not take Ondanbic unless your doctor advises you to do so -



Frequently asked Questions about Ondanbic

  • Is this Ondanbic habit forming or addictive?


    No, there is no any evidence that Ondanbic is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should do not do anything that requires concentration and attention as the Ondanbic can make you feel drowsy.

    Dangerous
  • Is it safe?


    Yes, but take Ondanbic only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Ondanbic cannot treat any kind of mental disorder.

    No

Ondanbic Interactions with Food and Alcohol

  • Interaction between Food and Ondanbic


    It is safe to take Ondanbic with food.

    Safe
  • Interaction between Alcohol and Ondanbic


    Taking Ondanbic with alcohol can have severely harmful effects on your health.

    Severe


Frequently asked Questions about Ondanbic

Question about 5 years ago

How to take Ondanbic?

Dr. Saurabh Shakya MBBS , General Physician

Ondanbic is available in form of tablet, syrup, and injection. It should be taken as per your doctor's instructions. Ideally, Ondanbic has to be taken with food to avoid stomach upset. The initial dose is usually taken half an hour before chemotherapy, 1 to 2 hours before radiation therapy and 1 hour before a surgery. Additional doses can be suggested by the doctor as per the individual requirements.

Question over 4 years ago

Can Ondanbic be taken with pantoprazole?

Dr. Ramraj Meena MBBS , General Physician

Yes, Ondanbic can be taken with pantoprazole as there are no records of any drug interaction. Pantoprazole is a proton pump inhibitor which is used for treating acidity. Acidity can be managed by avoiding eating acidic and spicy foods, avoiding smoking, and avoiding sleep within 3 hours of taking meals.

Question almost 5 years ago

Does Ondanbic cause constipation?

Dr. Ashish Mishra MBBS , Pathology

Yes, Ondanbic can cause constipation. Some of the other side effects are a headache and dizziness. Constipation is a debilitating disorder which can be prevented by drinking a lot of water, eating more of fiber, exercising more, taking herbal laxatives, taking probiotic food, and avoiding dairy products. 

Question about 5 years ago

How does Ondanbic work?

Dr. Uday Nath Sahoo MBBS , Internal Medicine

Ondanbic belongs to a class of compounds known as 5 -HT3 receptor antagonists. It blocks the action of serotonin completely at the 5-HT3 receptor sites present in our brain (vomiting centre) which provides relief to the patient from nausea and vomiting.

Question about 5 years ago

Can Ondanbic be taken for irritable bowel syndrome with diarrhea?

Dr. Vipin Khadse MBBS , General Physician

Yes, Ondanbic can be taken for the treatment of irritable bowel syndrome with diarrhea. Irritable bowel syndrome is a common gastrointestinal disorder affecting a lot of people. It causes gas, abdominal discomfort and changes in the bowel movement like diarrhea or constipation. The disease can be controlled by altering the diet and eating more of fibre and less of fats, alcohol, caffeine and spicy food. Increasing physical activity and reducing stress can also help greatly. 



See all substitutes for Ondanbic


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 947-948

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 668

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran (ondansetron hydrochloride)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran® (ondansetron hydrochloride)



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