Clozapine



  • Manufactured by:
  • Contains / Salt: Clozapine


Clozapine Information



Clozapine Benefits & Uses

Clozapine is used to treat the following -

Main Benefits

Other Benefits

Clozapine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Schizophrenia
  • Before or After Meal: After Meal
  • Single Maximum Dose: 12.5 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: gradually increase 25 - 50 mg/day over a period of 2 week up to target dose of 300 - 450 mg/day
Geriatric
  • Disease: Schizophrenia
  • Before or After Meal: After Meal
  • Single Maximum Dose: 12.5 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: gradually increase 25 - 50 mg/day over a period of 2 week up to target dose of 300 - 450 mg/day


Clozapine Side Effects

Based on research, the following side effects have been observed when Clozapine is used -

Moderate

Mild

Common

  • Blurred vision

Clozapine Related Warnings

  • Is the use of Clozapine safe for pregnant women?


    Pregnant women may get mild side effects from Clozapine.

    Mild
  • Is the use of Clozapine safe during breastfeeding?


    Clozapine should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

    Severe
  • What is the effect of Clozapine on the Kidneys?


    Very few cases of side effects of Clozapine on kidney have been reported.

    Mild
  • What is the effect of Clozapine on the Liver?


    Side effects of Clozapine rarely affect the liver.

    Mild
  • What is the effect of Clozapine on the Heart?


    Clozapine can have moderate side effects on the heart. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate


Severe Interaction of Clozapine with Other Drugs

Clozapine should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate

AcarboseChlorpheniramine,Dextromethorphan,Paracetamol,Phenylephrine
    Paracetamol,Tramadol


      Clozapine Contraindications

      If you are suffering from any of the following diseases, you should not take Clozapine unless your doctor advises you to do so -



      Frequently asked Questions about Clozapine

      • Is this Clozapine habit forming or addictive?


        Forming a habit of Clozapine has not been reported.

        No
      • Is it safe to drive or operate heavy machinery when consuming?


        No, you should not drive or operate heavy machinery after taking Clozapine as you may feel sleepy.

        Dangerous
      • Is it safe?


        Yes, but consume Clozapine only on doctor's advice.

        Safe, but take only on Doctor's advise
      • Is it able to treat mental disorders?


        Yes, this Clozapine works for mental disorders.

        Yes

      Clozapine Interactions with Food and Alcohol

      • Interaction between Food and Clozapine


        When consumed with certain foods, Clozapine may take longer to have an effect. Contact your doctor about this.

        Mild
      • Interaction between Alcohol and Clozapine


        Taking Clozapine with alcohol can have severely harmful effects on your health.

        Severe


      See all substitutes for Clozapine


      This medicine data has been created by -

      Vikas Chauhan

      B.Pharma, Pharmacy
      5 Years of Experience


      References

      US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Clozaril® (clozapine)

      KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 175,471

      April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 56-58

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