Defnalone

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  • Manufactured by: Lupin Ltd
  • Contains / Salt: Deflazacort (6 mg)
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Defnalone Information

Defnalone, a prescription drug, is manufactured in various forms such as Tablet, Suspension. Allergy, Asthma, Rheumatic Disorder are some of its major therapeutic uses. Defnalone also has some secondary and off-label uses. These are listed below.

The correct dosage of Defnalone depends on the patient's age, gender, and medical history. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Refer to the dosage section for a detailed discussion.

Some other side effects of Defnalone have been listed ahead. Usually, these side effects of Defnalone go away soon, and do not persist beyond the duration of the treatment. Consult your doctor if these side effects become worse or stay for a longer duration.

In addition, Defnalone's effect is Severe during pregnancy and Severe for lactating mothers. In addition, Defnalone's effects on the liver, heart and kidney are discussed below in the Defnalone related warnings section.

Defnalone can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Defnalone in conditions like Diabetes. Other conditions have been mentioned below in the Defnalone contraindications section.

Besides this, Defnalone may also have severe interaction with some medicines. A complete list of these interactions is given below.

You should also be aware that Defnalone is safe while driving, and is addiction.



Defnalone Benefits & Uses

Defnalone is used to treat the following -

Other Benefits

Defnalone Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Duchenne Muscular Dystrophy
  • Before or After Meal: With meal
  • Single Maximum Dose: 0.9 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Duchenne Muscular Dystrophy
  • Before or After Meal: With meal
  • Single Maximum Dose: 0.9 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

Defnalone Related Warnings

  • Is the use of Defnalone safe for pregnant women?


    Defnalone has many dangerous side effects in pregnant women. If you are pregnant, do not consume Defnalone without medical advice.

    Severe
  • Is the use of Defnalone safe during breastfeeding?


    Women who are breastfeeding, may experience serious side effects after taking Defnalone. So it is adviced to consult the doctor before using it.

    Severe
  • What is the effect of Defnalone on the Kidneys?


    Defnalone may cause harmful effects on kidney. if you feel its having any such effect, then stop taking this drug, and restart only on your doctor's advice.

    Moderate
  • What is the effect of Defnalone on the Liver?


    Defnalone may cause harmful effects on liver. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.

    Moderate
  • What is the effect of Defnalone on the Heart?


    Defnalone can have moderate side effects on the heart. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate


Severe Interaction of Defnalone with Other Drugs

Defnalone should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Defnalone Contraindications

If you are suffering from any of the following diseases, you should not take Defnalone unless your doctor advises you to do so -



Frequently asked Questions about Defnalone

  • Is this Defnalone habit forming or addictive?


    No, there is no any evidence that Defnalone is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Defnalone does not cause dizziness or sleep, so you can drive a vehicle or operate machinery also.

    Safe
  • Is it safe?


    Yes, but consume Defnalone only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Defnalone in mental disorders is not effective.

    No

Defnalone Interactions with Food and Alcohol

  • Interaction between Food and Defnalone


    Due to a lack of research, nothing can be said about the consequences of taking Defnalone together with food.

    Unknown
  • Interaction between Alcohol and Defnalone


    Due to lack of research, there is no information about the side effects of taking Defnalone with alcohol.

    Unknown


Frequently asked Questions about Defnalone

Question almost 5 years ago

Is Defnalone safe to use?

Dr. Saikat Mukherjee MBBS , General Physician

Yes, Defnalone is safe to use, if taken in prescribed amount for a specified time as advised by the doctor. However, some side effects are observed at regular doses these are joint pain, dizziness, stomach upset, and headache. Do not hesitate to inform your doctor if you are facing any of the above.

Question almost 5 years ago

Does Defnalone contain steroids?

Dr. Ramraj MBBS , Other

Yes, Defnalone belongs to the class of drugs called steroids (corticosteroid) which are used to treat allergic and inflammatory conditions. They should not be confused with anabolic-androgenic steroids which some body-builders use, without prescription to build muscle mass.

Question almost 5 years ago

Can I take Defnalone with Paracetamol?

Dr. Saikat Mukherjee MBBS , General Physician

Yes, Defnalone can be taken with paracetamol. No harmful drug interaction has been reported between them. However, if you feel any discomfort do discuss with your doctor.

Question about 5 years ago

How does Defnalone work?

Dr. R.K Singh MBBS , Diabetology

Defnalone works by suppressing body's normal immune response to inflammation (swelling). This results in reduced inflammation (swelling) and provides relief from the symptoms associated with the Duchenne muscular dystrophy.

Question about 5 years ago

Can I take Defnalone without consulting a doctor?

Dr. Vedprakash Verma MBBS, MD , Cardiology

No, Defnalone is a prescription drug so do not take it without consulting a doctor. It can be harmful for the patient to take this medicine without a doctor's recommendation because it suppresses the immune system that causes low immunity. Low immunity can further lead to multiple infections of bacterial and viral origins.



See all substitutes for Defnalone


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 289

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Emflaza™ (deflazacort)

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