Naloxone

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Naloxone Information



Naloxone Benefits & Uses

Naloxone is used to treat the following -

Main Benefits

Other Benefits

Naloxone Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Opioid Toxicity
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: Dose given up to 10 mg, IV, SC dose are also same
Geriatric
  • Disease: Opioid Toxicity
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: Dose given up to 10 mg, IV, SC dose are also same
13 - 18 years (Adolescent)
  • Disease: Opioid Toxicity
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 2 mg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: Dose for 5 to 17 years old children and weighing more than 20 kg
2 - 12 years (Child)
  • Disease: Opioid Toxicity
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.1 mg/kg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: Dose for 2 - 5 years old children only and younger than 20 kg
Infant (1 month to 2 years)
  • Disease: Opioid Toxicity
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.1 mg/kg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Neonates (0 to 1 month)
  • Disease: Opioid Toxicity
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.1 mg/kg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

Naloxone Related Warnings

  • Is the use of Naloxone safe for pregnant women?


    Pregnant women can take Naloxone safely.

    Safe
  • Is the use of Naloxone safe during breastfeeding?


    Naloxone is completely safe for breastfeeding women.

    Safe
  • What is the effect of Naloxone on the Kidneys?


    Naloxone has very mild side effects on the kidneys.

    Mild
  • What is the effect of Naloxone on the Liver?


    Very few cases of side effects of Naloxone on the liver have been reported.

    Mild
  • What is the effect of Naloxone on the Heart?


    Naloxone is rarely harmful for the heart.

    Mild


Severe Interaction of Naloxone with Other Drugs

Naloxone should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate



Naloxone Contraindications

If you are suffering from any of the following diseases, you should not take Naloxone unless your doctor advises you to do so -



Frequently asked Questions about Naloxone

  • Is this Naloxone habit forming or addictive?


    Naloxone is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, it is safe to do these activities or work after taking Naloxone as it does not make you drowsy.

    Safe
  • Is it safe?


    Naloxone should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Naloxone for mental disorders.

    No

Naloxone Interactions with Food and Alcohol

  • Interaction between Food and Naloxone


    Taking Naloxone with food does not cause any problems.

    Safe
  • Interaction between Alcohol and Naloxone


    No research has been done on this till date. Therefore, it is not known what the effect of taking Naloxone with alcohol will be.

    Unknown


See all substitutes for Naloxone


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 890-892

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 483

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Narcan® (naloxone hydrochloride)



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