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Onset is a prescription medicine that is available as a Tablet, Injection. Nausea and Vomiting are some of its major therapeutic uses.
The optimal dosage of Onset is largely dependent on the individual's body weight, medical history, gender and age. Individual symptoms and route of administration also determines the right dosage. For detailed information on this, read through the dosage section.
Apart from the aforementioned side effects, Onset can also lead to other problems, which have been listed below. Usually, these side effects of Onset go away soon, and do not persist beyond the duration of the treatment. If, however, they worsen or do not go away, please speak with your physician.
Onset's effect during pregnancy is Safe and Mild while nursing. In addition, Onset's effects on the liver, heart and kidney are discussed below in the Onset related warnings section.
Onset is not recommended if you suffer from certain medical conditions as it can have adverse effects. Heart Disease, Calcium Deficiency, Potassium Deficiency are examples of such conditions. The section on Onset contraindications lists all such conditions.
Besides this, Onset may also have severe interaction with some medicines. See below for a complete list.
In addition to the above precautions for Onset, it is important to know that it is not safe while driving, and is not habit-forming.
Onset is used to treat the following -
Main Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
13 - 18 years (Adolescent) |
|
2 - 12 years (Child) |
|
Infant (1 month to 2 years) |
|
Is the use of Onset safe for pregnant women?
Pregnant women can take Onset safely.
Is the use of Onset safe during breastfeeding?
Onset has been seen to have minimal side effects on breastfeeding women.
What is the effect of Onset on the Kidneys?
Onset is completely safe for kidneys.
What is the effect of Onset on the Liver?
The liver can be affected by Onset. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Onset only after medical advice.
What is the effect of Onset on the Heart?
Onset may cause harmful effects on the heart. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.
Onset should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Onset unless your doctor advises you to do so -
Is this Onset habit forming or addictive?
No, you will not get addicted to Onset.
Is it safe to drive or operate heavy machinery when consuming?
You may feel sleepy or tired after taking Onset. So it is best to avoid driving.
Is it safe?
Onset is safe but it is important to consult a doctor before taking it.
Is it able to treat mental disorders?
No, the use of Onset in mental disorders is not effective.
Interaction between Food and Onset
Taking Onset with food does not harm your health.
Interaction between Alcohol and Onset
Consumption of alcohol and Onset together may have severe effects on your health.
Yes, Onset can be taken with pantoprazole as there are no records of any drug interaction. Pantoprazole is a proton pump inhibitor which is used for treating acidity. Acidity can be managed by avoiding eating acidic and spicy foods, avoiding smoking, and avoiding sleep within 3 hours of taking meals.
Yes, Onset can be taken for the treatment of irritable bowel syndrome with diarrhea. Irritable bowel syndrome is a common gastrointestinal disorder affecting a lot of people. It causes gas, abdominal discomfort and changes in the bowel movement like diarrhea or constipation. The disease can be controlled by altering the diet and eating more of fibre and less of fats, alcohol, caffeine and spicy food. Increasing physical activity and reducing stress can also help greatly.
Onset is a brand name for ondansetron. It belongs to a class of compounds known as serotonin type 3 receptor antagonists. It is available in the form of tablet and injection. It is used to prevent nausea and vomiting that is caused by anti-cancer drugs, chemotherapy and radiation therapy. It is also used to prevent post-surgical nausea and vomiting.
Onset is available in form of tablet, syrup, and injection. It should be taken as per your doctor's instructions. Ideally, Onset has to be taken with food to avoid stomach upset. The initial dose is usually taken half an hour before chemotherapy, 1 to 2 hours before radiation therapy and 1 hour before a surgery. Additional doses can be suggested by the doctor as per the individual requirements.
Yes, Onset is safe to be used in children from 6 months to 12 years of age. Apart from preventing nausea and vomiting related to chemotherapy and radiation, Onset can be used in this population group for managing acute gastritis. Acute gastritis presents itself as a self-limited infection with vomiting leading to dehydration and electrolyte imbalances. Always check with a child specialist and do not administer this drug yourself.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 947-948
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 668
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran (ondansetron hydrochloride)
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran® (ondansetron hydrochloride)