Onsetrin

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  • Contains / Salt: Ondansetron (2 mg)
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Onsetrin Information

Onsetrin is a commercial drug that is prescribed in the form of Injection, Tablet. Nausea and Vomiting are some of its major therapeutic uses.

The right dosage of Onsetrin depends on the age, gender, and medical history of the patient. The condition it has been prescribed for, and the route of administration also determine the right dosage. This information has been provided in detail in the dosage section.

While these are the most often observed Onsetrin side effects, there are can be others also. These have been listed below. These side effects of Onsetrin are usually temporary and subside with the completion of treatment. Consult your doctor if these side effects become worse or stay for a longer duration.

Furthermore, you should know that effect of Onsetrin is Safe for pregnant women and Mild for women who are breastfeeding. In addition, Onsetrin's effects on the liver, heart and kidney are discussed below in the Onsetrin related warnings section.

Individuals suffering from medical conditions like Heart Disease, Calcium Deficiency, Potassium Deficiency must refrain from the use of Onsetrin since this can cause severe adverse effects. Some other conditions that can be affected by Onsetrin are listed in the contraindications section below.

Additionally, Onsetrin may also adversely react with other medicines. See below for a complete list.

In addition to these precautions, you may also note that Onsetrin is not safe while driving, and is is not addictive in nature.



Onsetrin Benefits & Uses

Onsetrin is used to treat the following -

Onsetrin Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
Geriatric
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
13 - 18 years (Adolescent)
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
2 - 12 years (Child)
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
Infant (1 month to 2 years)
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy. Given dose older then 6 month


Onsetrin Side Effects

Based on research, the following side effects have been observed when Onsetrin is used -

Moderate

Mild

Onsetrin Related Warnings

  • Is the use of Onsetrin safe for pregnant women?


    Pregnant women can take Onsetrin without worrying about any side effects.

    Safe
  • Is the use of Onsetrin safe during breastfeeding?


    Onsetrin may have very limited harmful effects for breastfeeding women.

    Mild
  • What is the effect of Onsetrin on the Kidneys?


    Onsetrin is not harmful for kidneys.

    Safe
  • What is the effect of Onsetrin on the Liver?


    Onsetrin may cause harmful effects on liver. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.

    Moderate
  • What is the effect of Onsetrin on the Heart?


    The heart can be affected by Onsetrin. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart the medicine only after medical advice.

    Moderate


Severe Interaction of Onsetrin with Other Drugs

Onsetrin should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Onsetrin Contraindications

If you are suffering from any of the following diseases, you should not take Onsetrin unless your doctor advises you to do so -



Frequently asked Questions about Onsetrin

  • Is this Onsetrin habit forming or addictive?


    Forming a habit of Onsetrin has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    You may feel sleepy or tired after taking Onsetrin. So it is best to avoid driving.

    Dangerous
  • Is it safe?


    Onsetrin is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Onsetrin in mental disorders is not effective.

    No

Onsetrin Interactions with Food and Alcohol

  • Interaction between Food and Onsetrin


    Taking Onsetrin with food is safe.

    Safe
  • Interaction between Alcohol and Onsetrin


    Consuming Onsetrin with alcohol can have many serious effects on your body.

    Severe


Frequently asked Questions about Onsetrin

Question over 4 years ago

Can Onsetrin be taken with tramadol?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

No, Onsetrin should not be ideally taken with tramadol as the action of both the drugs decreases upon concomitant use. Tramadol is an opioid medication used to treat mild to moderate pain. Take it only when a doctor has prescribed it. ​

Question almost 5 years ago

Does Onsetrin cause drowsiness?

Dr. Rahul Poddar MBBS, DNB, MBBS, DNB , General Surgery

Yes, Onsetrin may cause drowsiness because this drug has been reported to induce sleep. Ensure you do not drive or do some high precision work. To avoid excessive drowsiness with this medicine you are encouraged to take adequate night-time sleep, keeping distractions out of the bedroom, going to sleep and getting up at consistent times, eating light at lunchtime, putting in some form of a physical activity, avoiding taking naps during the day, and avoiding alcohol at night.

Question about 5 years ago

What is Onsetrin?

Dr Anjum Mujawar MBBS, MBBS , Emergency Medicine

Onsetrin is a brand name for ondansetron. It belongs to a class of compounds known as serotonin type 3 receptor antagonists. It is available in the form of tablet and injection. It is used to prevent nausea and vomiting that is caused by anti-cancer drugs, chemotherapy and radiation therapy. It is also used to prevent post-surgical nausea and vomiting. 

Question over 4 years ago

Can Onsetrin be used for anxiety?

Dr. Piyush Malav MBBS, MS , General Surgery

Yes, Onsetrin can be used for the symptom alleviation in anxiety, however, more clinical trials are needed to confirm this association. Anxiety can also be effectively managed by breathing deeply, practicing meditation, and not taking much stress. In case of severe anxiety please speak to your doctor.

Question over 4 years ago

Does Onsetrin cause headache?

Dr. MBBS , General Physician, Other, Obstetrics & Gynaecology

Yes, headache is one of the common side effects of Onsetrin. Apply balms and take a mild painkiller if a headache is of throbbing nature. Additionally, headaches can be prevented by doing yoga and meditation, by keeping away from electronic gadgets and computers, by eating light food and listening to relaxing music.



See all substitutes for Onsetrin


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 947-948

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 668

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran (ondansetron hydrochloride)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran® (ondansetron hydrochloride)



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