Asginase Information

Asginase is a commercial drug that is prescribed in the form of Injection. It is typically used for the treatment of Blood Cancer.

Medical history of the patient along with age and gender determines the dosage of Asginase. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Refer to the dosage section for a detailed discussion.

Asginase also has some side effects, the most common being Rash, Nausea or vomiting, Increased Liver Enzymes. Usually, these side effects of Asginase go away soon, and do not persist beyond the duration of the treatment. However, if these continue for a longer time, consult your doctor right away.

Furthermore, you should know that effect of Asginase is Moderate for pregnant women and Severe for women who are breastfeeding. It is important to know if Asginase has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Asginase related warnings section.

Individuals suffering from medical conditions like Bleeding, Pancreatitis must refrain from the use of Asginase since this can cause severe adverse effects. Other contraindications of Asginase have been discussed in the sections ahead.

Drug interactions for Asginase have been reported in the medical literature. See below for a complete list.

You should also be aware that Asginase is not safe while driving, and is not addiction.

Asginase Benefits & Uses
Asginase Dosage & How to Take
Asginase Side Effects
Asginase Related Warnings
Severe Interaction of Asginase with Other Drugs
Asginase Contraindications
Frequently asked Questions about Asginase
Asginase Interactions with Food and Alcohol

Asginase Benefits & Uses

Asginase is used to treat the following -

Other Benefits

Chronic Myelogenous Leukemia

Asginase Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
13 - 18 years (Adolescent)	Disease: Blood Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 200 units/kg Dosage Route: Parenteral Frequency: 1 daily Course Duration: 4 weeks Special Instructions: As prescribed by the doctor
2 - 12 years (Child)	Disease: Blood Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 200 units/kg Dosage Route: Parenteral Frequency: 1 daily Course Duration: 4 weeks Special Instructions: As prescribed by the doctor

Asginase Related Warnings

Is the use of Asginase safe for pregnant women?

Pregnant women may experience moderate side effects from Asginase. It is best to stop taking Asginase immediately and inform your doctor if you notice any discomfort.

Moderate
Is the use of Asginase safe during breastfeeding?

Women who are breastfeeding may experience severe harmful effects after taking Asginase. It should only be taken after medical advice.

Severe
What is the effect of Asginase on the Kidneys?

Asginase rarely harms the kidneys.

Mild
What is the effect of Asginase on the Liver?

There may be an adverse effect on the liver after taking Asginase. If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.

Moderate
What is the effect of Asginase on the Heart?

You can take Asginase without any fear of damage to the heart.

Safe

Severe Interaction of Asginase with Other Drugs

Asginase should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Thalidomide

Moderate

Acarbose

Alogliptin

Alogliptin Tablet

Metformin

Methotrexate

Carbamazepine

Asginase Contraindications

If you are suffering from any of the following diseases, you should not take Asginase unless your doctor advises you to do so -

Liver Disease
Bleeding
Pancreatitis
Diabetes

Frequently asked Questions about Asginase

Is this Asginase habit forming or addictive?

Forming a habit of Asginase has not been reported.

No
Is it safe to drive or operate heavy machinery when consuming?

No, you should not drive or operate heavy machinery after taking Asginase as you may feel sleepy.

Dangerous
Is it safe?

Yes, but take Asginase only as per medical advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

Asginase is unable to treat or cure mental disorders.

No

Asginase Interactions with Food and Alcohol

Interaction between Food and Asginase

Taking Asginase with food does not harm your health.

Safe
Interaction between Alcohol and Asginase

It is difficult to say anything about the effect of Asginase and alcohol. No research has been done on this yet.

Unknown

See all substitutes for Asginase

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Elspar® (Asparaginase)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 868-869

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 190-191

Asginase