Mifepristone

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  • Contains / Salt: Mifepristone

Mifepristone Information



Mifepristone Benefits & Uses

Mifepristone is used to treat the following -

Other Benefits

Mifepristone Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Cushing's Syndrome
  • Before or After Meal: With meal
  • Single Maximum Dose: 300 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Cushing's Syndrome
  • Before or After Meal: With meal
  • Single Maximum Dose: 300 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult(Female)
  • Disease: Abortion
  • Before or After Meal: Either
  • Single Maximum Dose: 200 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: once only
  • Course Duration: 3 days
  • Special Instructions: 24 to 48 hrs after 1st dose patient should place two 200 mcg misoprostol tablets in each cheek pouch and swallow it after 30min


Mifepristone Side Effects

Based on research, the following side effects have been observed when Mifepristone is used -

Severe

Moderate

Mild

Common

  • Uterine Cramps
  • Uterine Bleeding

Mifepristone Related Warnings

  • Is the use of Mifepristone safe for pregnant women?


    Mifepristone shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

    Severe
  • Is the use of Mifepristone safe during breastfeeding?


    Mifepristone may lead to some side effects in breastfeeding women. If you witness any unusal symptoms after taking Mifepristone, discontinue its use and call your doctor right away. Follow your doctor's advice regarding the use of Mifepristone.

    Moderate
  • What is the effect of Mifepristone on the Kidneys?


    Very few cases of side effects of Mifepristone on kidney have been reported.

    Mild
  • What is the effect of Mifepristone on the Liver?


    You may experience side effects on your liver after taking Mifepristone. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.

    Moderate
  • What is the effect of Mifepristone on the Heart?


    Mifepristone has very mild side effects on the heart.

    Mild


Severe Interaction of Mifepristone with Other Drugs

Mifepristone should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate

Mild



Mifepristone Contraindications

If you are suffering from any of the following diseases, you should not take Mifepristone unless your doctor advises you to do so -



Frequently asked Questions about Mifepristone

  • Is this Mifepristone habit forming or addictive?


    Mifepristone does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should do not do anything that requires concentration and attention as the Mifepristone can make you feel drowsy.

    Dangerous
  • Is it safe?


    Yes, but consume Mifepristone only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Mifepristone is unable to treat or cure mental disorders.

    No

Mifepristone Interactions with Food and Alcohol

  • Interaction between Food and Mifepristone


    Due to the absence of research, it is difficult to say how Mifepristone and food will interact.

    Unknown
  • Interaction between Alcohol and Mifepristone


    Due to lack of research, there is no information about the side effects of taking Mifepristone with alcohol.

    Unknown


Frequently asked Questions about Mifepristone

Question over 4 years ago

Can I take Mifepristone with alcohol?

Dr. Bharat MBBS , General Physician

No harmful interactions are found between Mifepristone and alcohol, it does not reduce the effectiveness of the drug. However, alcohol can cause liver damage and dehydration in some people which may increase the severity of side effects, if taken together. So, it is better to avoid taking Mifepristone with alcohol.

Question about 5 years ago

How to use Mifepristone?

Dr. Tarun kumar MBBS , Other

Take Mifepristone as directed by your doctor. After taking Mifepristone you should wait 24 to 48 hours for the onset of bleeding. Please consult your doctor, before taking the abortion pill. In case of heavy bleeding contact your doctor without any delay.

Question about 5 years ago

Does Mifepristone cause bleeding?

Dr. Kishan Barnwal MBBS , General Physician

Mifepristone alone does not cause bleeding, although some women may experience light bleeding after taking misoprostol.

Question almost 5 years ago

What are the symptoms of Mifepristone overdose?

Dr. Ayush Pandey MBBS, PG Diploma , General Physician

Mifepristone overdose, should be observed closely for signs of adrenal failure, trouble breathing. Symptoms of overdose may include: severe vaginal bleeding, Nausea, vomiting, diarrhea, weakness, or dizziness may occur.

Question about 5 years ago

What does Mifepristone treat?

Dr. Ayush Pandey MBBS, PG Diploma , General Physician

Mifepristone is used in combination with misoprostol to terminate early pregnancy. Early pregnancy means it has been 10 weeks or less since your last menstrual cycle began. It is also used to control hyperglycemia in people with Cushing syndrome.



See all substitutes for Mifepristone


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 858-859

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 319-320

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Mifeprex® (mifepristone)



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