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Silymarin + Ursodiol (Ursodeoxycholic Acid) is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
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Geriatric |
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Based on research, the following side effects have been observed when Silymarin + Ursodiol (Ursodeoxycholic Acid) is used -
Common
Is the use of Silymarin + Ursodiol (Ursodeoxycholic Acid) safe for pregnant women?
Pregnant women may experience moderate side effects from Silymarin + Ursodiol (Ursodeoxycholic Acid). It is best to stop taking Silymarin + Ursodiol (Ursodeoxycholic Acid) immediately and inform your doctor if you notice any discomfort.
Is the use of Silymarin + Ursodiol (Ursodeoxycholic Acid) safe during breastfeeding?
Women who are breastfeeding may experience severe harmful effects after taking Silymarin + Ursodiol (Ursodeoxycholic Acid). It should only be taken after medical advice.
What is the effect of Silymarin + Ursodiol (Ursodeoxycholic Acid) on the Kidneys?
There may be some severe side effects of Silymarin + Ursodiol (Ursodeoxycholic Acid) on your kidney. Do not take it unless a doctor says so.
What is the effect of Silymarin + Ursodiol (Ursodeoxycholic Acid) on the Liver?
Silymarin + Ursodiol (Ursodeoxycholic Acid) is not harmful for the liver.
What is the effect of Silymarin + Ursodiol (Ursodeoxycholic Acid) on the Heart?
Silymarin + Ursodiol (Ursodeoxycholic Acid) may cause harmful effects on the heart. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.
Silymarin + Ursodiol (Ursodeoxycholic Acid) should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Silymarin + Ursodiol (Ursodeoxycholic Acid) unless your doctor advises you to do so -
Is this Silymarin + Ursodiol (Ursodeoxycholic Acid) habit forming or addictive?
Silymarin + Ursodiol (Ursodeoxycholic Acid) does not cause addiction.
Is it safe to drive or operate heavy machinery when consuming?
No, you should do not do anything that requires concentration and attention as the Silymarin + Ursodiol (Ursodeoxycholic Acid) can make you feel drowsy.
Is it safe?
Yes, but take Silymarin + Ursodiol (Ursodeoxycholic Acid) only as per medical advice.
Is it able to treat mental disorders?
Silymarin + Ursodiol (Ursodeoxycholic Acid) is unable to treat or cure mental disorders.
Interaction between Food and Silymarin + Ursodiol (Ursodeoxycholic Acid)
Due to the absence of research, it is difficult to say how Silymarin + Ursodiol (Ursodeoxycholic Acid) and food will interact.
Interaction between Alcohol and Silymarin + Ursodiol (Ursodeoxycholic Acid)
Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Silymarin + Ursodiol (Ursodeoxycholic Acid).
Silymarin + Ursodiol (Ursodeoxycholic Acid) is used in the treatment of fatty liver in combination with other drugs. It helps in improving liver functions with assists in speedy recovery.
Silymarin + Ursodiol (Ursodeoxycholic Acid) contains silymarin which is a polyphenolic flavonoid obtained from plant milk thistle (Silybum marianum). It is presumed that Silymarin + Ursodiol (Ursodeoxycholic Acid) works through multiple mechanisms. It prevents the formation of reactive oxygen species (free radicals) that damages the liver which affects its normal functioning. It also reduces the inflammation and stimulates the liver cells to produce proteins.
Yes, Silymarin + Ursodiol (Ursodeoxycholic Acid) lowers the SGPT (serum glutamic pyruvic transaminase or alanine transaminase) levels in the blood. This occurs due to the hepatoprotective (liver protective) action of this drug which helps in preventing the liver damage that lowers the SGPT levels in our blood.
Yes, Silymarin + Ursodiol (Ursodeoxycholic Acid) lowers cholesterol levels in the blood because it inhibits the synthesis of bad cholesterol (LDL and VLDL) and it also increases the levels of good cholesterol (HDL) in our body.
No, Silymarin + Ursodiol (Ursodeoxycholic Acid) should not be discontinued without doctors advice. You are recommended to always consult a doctor before discontinuing this medicine.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1344-1345
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 671
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Urso 250® / Urso Forte® (ursodiol)
Highlights of Prescribing Information [Internet]: URSO 250® / URSO Forte® (ursodiol) TABLETS . Initial U.S. Approval: 1997
Gholamreza Karimi,1,* Maryam Vahabzadeh,2 Parisa Lari,2 Marziyeh Rashedinia,2 and Mohammad Moshiri2 [Internet]: “Silymarin”, a Promising Pharmacological Agent for Treatment of Diseases. PMCID: PMC3586829 PMID: 23492971