Topirain

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  • Contains / Salt: Topiramate (50 mg)
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Topirain Information

Topirain is a commercial drug that is prescribed in the form of Tablet. Epilepsy are some of its major therapeutic uses. Secondary and off-label uses of Topirain have also been mentioned below.

The optimal dosage of Topirain is largely dependent on the individual's body weight, medical history, gender and age. The condition it has been prescribed for, and the route of administration also determine the right dosage. Detailed information has been provided in the dosage section.

Apart from the aforementioned side effects, Topirain can also lead to other problems, which have been listed below. Normally, these side effects of Topirain are not long lasting and go away when the treatment is finished. Please speak with your doctor if these side effects worsen or persist for a longer duration.

Topirain's effect during pregnancy is Moderate and Mild while nursing. Further, the section on Topirain related warnings talks about Topirain's effects on the liver, heart and kidney.

Topirain can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Topirain in conditions like Suicidal Tendency, Liver Disease. Some other conditions that can be affected by Topirain are listed in the contraindications section below.

Additionally, Topirain may also adversely react with other medicines. A complete list of these interactions is given below.

You should also be aware that Topirain is not safe while driving, and is not addiction.



Topirain Benefits & Uses

Topirain is used to treat the following -

Main Benefits

Other Benefits

Topirain Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Migraine
  • Before or After Meal: Either
  • Single Maximum Dose: 25 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: gradually increases upto 50 mg twice daily
Geriatric
  • Disease: Migraine
  • Before or After Meal: Either
  • Single Maximum Dose: 25 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: gradually increases upto 50 mg twice daily
13 - 18 years (Adolescent)
  • Disease: Migraine
  • Before or After Meal: Either
  • Single Maximum Dose: 25 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: gradually increases upto 50 mg twice daily
2 - 12 years (Child)
  • Disease: Epilepsy
  • Before or After Meal: Either
  • Single Maximum Dose: 25 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: gradually increases upto 350 mg/day


Topirain Side Effects

Based on research, the following side effects have been observed when Topirain is used -

Moderate

Mild

  • Dizziness
  • Sleepiness
  • Nausea or vomiting
  • Paresthesia
  • Diarrhoea
  • Fatigue
  • पेट दर्द
  • Tiredness

Topirain Related Warnings

  • Is the use of Topirain safe for pregnant women?


    Topirain may cause moderate side effects during pregnancy. If you feel its harmful effects, then stop taking this drug immediately, and do not take Topirain again without your doctor's advice.

    Moderate
  • Is the use of Topirain safe during breastfeeding?


    Side effects of Topirain on breastfeeding women are very mild.

    Mild
  • What is the effect of Topirain on the Kidneys?


    Very few cases of side effects of Topirain on kidney have been reported.

    Mild
  • What is the effect of Topirain on the Liver?


    Topirain has very mild side effects on the liver.

    Mild
  • What is the effect of Topirain on the Heart?


    There are no any side effects of Topirain for the heart.

    Safe


Severe Interaction of Topirain with Other Drugs

Topirain should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate



Topirain Contraindications

If you are suffering from any of the following diseases, you should not take Topirain unless your doctor advises you to do so -



Frequently asked Questions about Topirain

  • Is this Topirain habit forming or addictive?


    Topirain is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should not drive or operate heavy machinery after taking Topirain as you may feel sleepy.

    Dangerous
  • Is it safe?


    Yes, but consume Topirain only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Yes, in many cases, taking Topirain can help with mental disorders.

    Yes

Topirain Interactions with Food and Alcohol

  • Interaction between Food and Topirain


    Taking Topirain with food does not harm your health.

    Safe
  • Interaction between Alcohol and Topirain


    Consumption of alcohol and Topirain together may have severe effects on your health.

    Severe


See all substitutes for Topirain


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1018-1019

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 420

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Topamax® (topiramate)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Trokendi XR (topiramate)



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