Avastin

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Avastin Information

Avastin is a commercial drug that is prescribed in the form of Injection, Tablet. Primarily, it is used for the treatment of High Cholesterol. Avastin also has some secondary and off-label uses. These are listed below.

The optimal dosage of Avastin is largely dependent on the individual's body weight, medical history, gender and age. Individual symptoms and route of administration also determines the right dosage. Detailed information has been provided in the dosage section.

Common side effects of Avastin include Headache, Nasopharyngitis, Diarrhoea. Besides the aforementioned side effects, there are other adverse effects of Avastin as well, which are listed below. These side effects of Avastin are usually temporary and subside with the completion of treatment. If, however, they worsen or do not go away, please speak with your physician.

In addition, Avastin's effect is Severe during pregnancy and Mild for lactating mothers. Further, the section on Avastin related warnings talks about Avastin's effects on the liver, heart and kidney.

Avastin is contraindicated in people with pre-existing medical conditions like Liver Disease, Alcoholism as it can result in adverse effects. Other contraindications of Avastin have been discussed in the sections ahead.

Additionally, Avastin may also adversely react with other medicines. See below for a complete list.

In addition to the above precautions for Avastin, it is important to know that it is safe while driving, and is habit-forming.



Avastin Benefits & Uses

Avastin is used to treat the following -

Other Benefits

Avastin Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
13 - 18 years (Adolescent)
  • Disease: High Cholesterol
  • Before or After Meal: Either
  • Single Maximum Dose: 20 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult
  • Disease: High Cholesterol
  • Before or After Meal: Either
  • Single Maximum Dose: 40 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: High Cholesterol
  • Before or After Meal: Either
  • Single Maximum Dose: 40 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

Avastin Related Warnings

  • Is the use of Avastin safe for pregnant women?


    Avastin can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

    Severe
  • Is the use of Avastin safe during breastfeeding?


    Avastin has been seen to have minimal side effects on breastfeeding women.

    Mild
  • What is the effect of Avastin on the Kidneys?


    There may be some adverse effects on kidney after taking Avastin. If you observe any such side effects, stop taking this drug. Consume this medicine again only if your doctor advises you to do so.

    Moderate
  • What is the effect of Avastin on the Liver?


    There may be an adverse effect on the liver after taking Avastin. If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.

    Moderate
  • What is the effect of Avastin on the Heart?


    Avastin may have mild side effects on the heart. Most people will never see any effect on the heart.

    Mild


Severe Interaction of Avastin with Other Drugs

Avastin should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Avastin Contraindications

If you are suffering from any of the following diseases, you should not take Avastin unless your doctor advises you to do so -



Frequently asked Questions about Avastin

  • Is this Avastin habit forming or addictive?


    Forming a habit of Avastin has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can operate a vehicle or heavy machinery after taking Avastin since it does not cause drowsiness.

    Safe
  • Is it safe?


    Avastin is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Avastin is not used to treat mental disorders.

    No

Avastin Interactions with Food and Alcohol

  • Interaction between Food and Avastin


    Taking Avastin with some specific foods may delay its effect. Talk to your doctor about this.

    Mild
  • Interaction between Alcohol and Avastin


    Taking alcohol with Avastin can be dangerous.

    Severe


Frequently asked Questions about Avastin

Question almost 5 years ago

Can I take Avastin in the morning?

Dr. MBBS , General Physician, Other, Obstetrics & Gynaecology

Yes, Avastin can be taken in the morning. It can be taken anytime once in a day with food or without food or as advised by your doctor.

Question almost 5 years ago

Does Avastin cause hair loss?

Dr. MBBS , General Physician, Other, Obstetrics & Gynaecology

Yes, Avastin might cause hair loss but it occurs very rarely. This problem goes away after discontinuation of the drug. However, if you notice excessive hair loss then consult it with your doctor.

Question about 5 years ago

How does Avastin work?

Dr. Chinmaya Bal MBBS , General Physician

Avastin works by inhibiting an enzyme (HMG-CoA reductase) which is responsible for cholesterol synthesis in our body, its inhibition results in increased levels of HDL (good cholesterol) and decreased levels of LDL (bad cholesterol) which lowers the risk of developing heart disease and helps in preventing strokes

Question about 5 years ago

Can I use Avastin without consulting a doctor?

Dr. Ajay Kumar MBBS, MD , General Physician

No, Avastin is a prescription drug so do not take it without consulting a doctor. It can be harmful for the patient to take this medicine without a doctor's recommendation because it can cause very unpleasant side effects. Hence, patient should seek doctors advice before taking this medication by himself or herself.

Question about 5 years ago

How long can I safely use Avastin?

Dr. Vipin Khadse MBBS , General Physician

Use Avastin as advised by your doctor. Do not discontinue the drug suddenly or use it longer than prescribed by your doctor.



See all substitutes for Avastin


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Lipitor® (Atorvastatin Calcium)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 637-638

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 646-650

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