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Itr is a prescription medicine that is available as a Capsule, Drops, Tablet. It is primarily used for the treatment of Fungal Infections, Candidal Infection. Itr also has some secondary and off-label uses. These are listed below.
Medical history of the patient along with age and gender determines the dosage of Itr. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. This information has been provided in detail in the dosage section.
Some other side effects of Itr have been listed ahead. Usually, these side effects of Itr go away soon, and do not persist beyond the duration of the treatment. Please speak with your doctor if these side effects worsen or persist for a longer duration.
Itr's effect during pregnancy is Moderate and Severe while nursing. Warnings related to Itr's effects on the liver, heart and kidney, if any, have been listed below.
Itr is not recommended if you suffer from certain medical conditions as it can have adverse effects. Coronary Artery Disease (CAD), Heart Disease, Liver Disease are examples of such conditions. Other contraindications of Itr have been discussed in the sections ahead.
Drug reaction of Itr with other medicines has been reported. See below for a complete list.
You should also be aware that Itr is not safe while driving, and is not addiction.
Itr is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
Based on research, the following side effects have been observed when Itr is used -
Severe
Moderate
Mild
Is the use of Itr safe for pregnant women?
Itr can cause unwanted side effects in pregnant women. If you experience any side effects, stop taking Itr right away. Take your doctor's advice before taking it again.
Is the use of Itr safe during breastfeeding?
Taking Itr may lead to serious side effects if you are breastfeeding. Itr should not be taken by breastfeeding women unless prescribed by the doctor.
What is the effect of Itr on the Kidneys?
Itr rarely affects the kidneys.
What is the effect of Itr on the Liver?
Itr has very mild side effects on the liver.
What is the effect of Itr on the Heart?
Side effects of Itr rarely affect the heart.
Itr should not be taken with following medicines due to severe side effects it may cause to patients -
Life Threatening
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Itr unless your doctor advises you to do so -
Is this Itr habit forming or addictive?
Itr is not addictive in nature.
Is it safe to drive or operate heavy machinery when consuming?
You may feel sleepy or tired after taking Itr. So it is best to avoid driving.
Is it safe?
Itr should be used only after doctor's advice.
Is it able to treat mental disorders?
No, Itr cannot treat any kind of mental disorder.
Interaction between Food and Itr
Taking Itr with food does not harm your health.
Interaction between Alcohol and Itr
Taking Itr with alcohol can have severely harmful effects on your health.
No, usually Itr does not cause nephrotoxicity. However, patients suffering from kidney disorders should take precaution before taking this medicine and get there kidney function test's (KFT) done to ensure proper functioning of the kidney's.
Yes, Itr can sometimes affect the liver by increasing the secretion of liver enzymes which can damage the liver cells. Rare cases of serious hepatotoxicity (liver damage), including liver failure and death have been reported.
Itraconazole works by preventing the fungal infection to grow further. They inhibit cytochrome P450 enzyme 14- demethylase and block ergosterol synthesis. This action results in the destruction of cell membranes of the pathogen by limiting the growth of the fungus.
Yes, Itr is known to cause stomach upset such as indigestion, pancreatitis, stomach pain, diarrhea, constipation, gastritis, and nausea. Please inform your doctor if you are experiencing these symptoms after using this medication.
Yes, Itr can cause hair loss if taken for a long time. However, if you're experiencing hair loss after taking this drug for a short duration then inform your doctor without any further delay.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Sporanox ® (itraconazole)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 794-795