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Nicophenicol is a commercial drug that is prescribed in the form of Capsule. It is primarily used for the treatment of Bacterial Infections. Nicophenicol also has some secondary and off-label uses. These are listed below.
The optimal dosage of Nicophenicol is largely dependent on the individual's body weight, medical history, gender and age. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Detailed information has been provided in the dosage section.
Besides the aforementioned side effects, there are other adverse effects of Nicophenicol as well, which are listed below. Usually, these side effects of Nicophenicol go away soon, and do not persist beyond the duration of the treatment. Please speak with your doctor if these side effects worsen or persist for a longer duration.
Furthermore, you should know that effect of Nicophenicol is Severe for pregnant women and Severe for women who are breastfeeding. Further, the section on Nicophenicol related warnings talks about Nicophenicol's effects on the liver, heart and kidney.
Nicophenicol is contraindicated in people with pre-existing medical conditions like Kidney Disease, Liver Disease as it can result in adverse effects. Other contraindications of Nicophenicol have been discussed in the sections ahead.
Additionally, Nicophenicol may also adversely react with other medicines. See below for a complete list.
You should also be aware that Nicophenicol is safe while driving, and is addiction.
Nicophenicol is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
13 - 18 years (Adolescent) |
|
Is the use of Nicophenicol safe for pregnant women?
Nicophenicol shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.
Is the use of Nicophenicol safe during breastfeeding?
Taking Nicophenicol may lead to serious side effects if you are breastfeeding. Nicophenicol should not be taken by breastfeeding women unless prescribed by the doctor.
What is the effect of Nicophenicol on the Kidneys?
Nicophenicol has very mild side effects on the kidneys.
What is the effect of Nicophenicol on the Liver?
You may experience side effects on your liver after taking Nicophenicol. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.
What is the effect of Nicophenicol on the Heart?
The heart can be affected by Nicophenicol. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart the medicine only after medical advice.
Nicophenicol should not be taken with following medicines due to severe side effects it may cause to patients -
Moderate
If you are suffering from any of the following diseases, you should not take Nicophenicol unless your doctor advises you to do so -
Is this Nicophenicol habit forming or addictive?
Nicophenicol is not addictive in nature.
Is it safe to drive or operate heavy machinery when consuming?
Nicophenicol will not make you feel sleepy or drowsy. So you drive or operate machinery safely.
Is it safe?
Yes, Nicophenicol is safe but you must consult your doctor before taking it.
Is it able to treat mental disorders?
Nicophenicol is unable to treat or cure mental disorders.
Interaction between Food and Nicophenicol
When consumed with certain foods, Nicophenicol may take longer to have an effect. Contact your doctor about this.
Interaction between Alcohol and Nicophenicol
Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Nicophenicol.
Yes, Nicophenicol may cause gray baby syndorme in newborn infants especially in premature baby, if this drug is given in higher doses. Gray baby syndrome is a rare side effect that occurs due to accumulation of the chloramphenicol in the newborn infant. The cause of gray baby syndrome is that the newborn baby lacks the some liver enzymes which are necessary to metabolize and removes this drug from the body. The accumulation of the chloramphenicol in the body leads to toxicity which causes development of symptoms such as vomiting, gray color of the skin, blue discoloration of lips and skin. To avoid gray baby syndrome the doses of Nicophenicol must be lowered and adjusted as per the need.
Yes, Nicophenicol can cause blurred vision (optic neuritis) but this occurs in a few cases only. It is a known side effect of this drug and it is reversible in nature. Usually, the vision is restored after discontinuation of this drug.
Yes, Nicophenicol can be taken with ibuprofen. No harmful drug interaction has been reported between them. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.
Discontinuing Nicophenicol on your own can increase the chances of bacterial resistance and infection relapse. It is recommended that you always consult your doctor if you have decided to discontinue this medicine.
Nicophenicol contains chloramphenicol which is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It works by inhibiting the protein synthesis in bacteria which needs to survive. In the absence of protein, the bacterial growth is stunned and slowed. It can also kill the bacteria in higher doses. Nicophenicol is effective against a wide range of both gram negative and gram positive bacteria such as Salmonella species, Rickettsia species, Neisseria meningitidis, Escherichia coli, Haemophilus influenzae, and Staphylococcus pneumoniae.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Chloromycetin sodium succinate (chaloramphenicol sodium succinate)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 739-742