Peeline M

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Peeline M Information

Peeline M, a prescription drug, is manufactured in various forms such as Tablet. Other than this, Peeline M has some other therapeutic uses, which have been discussed ahead.

The correct dosage of Peeline M depends on the patient's age, gender, and medical history. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. This information has been provided in detail in the dosage section.

The side effects typically associated with Peeline M include Stomach Upset, Difficulty urinating, Muscle Ache. Apart from the aforementioned side effects, Peeline M can also lead to other problems, which have been listed below. These side effects of Peeline M are usually temporary and subside with the completion of treatment. Please speak with your doctor if these side effects worsen or persist for a longer duration.

Furthermore, you should know that effect of Peeline M is Moderate for pregnant women and Moderate for women who are breastfeeding. In addition, Peeline M's effects on the liver, heart and kidney are discussed below in the Peeline M related warnings section.

Individuals suffering from medical conditions like Congestive Heart Failure (CHF), Anemia, Shock must refrain from the use of Peeline M since this can cause severe adverse effects. The section on Peeline M contraindications lists all such conditions.

Drug reaction of Peeline M with other medicines has been reported. See below for a complete list.

In addition to these precautions, you may also note that Peeline M is safe while driving, and is is addictive in nature.



Peeline M Benefits & Uses

Peeline M is used to treat the following -

Other Benefits

  • Diabetes Type 2

Peeline M Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 515 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: strength 15 mg pioglitazone and 500 mg metformin
Geriatric
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 865 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: strength 15 mg pioglitazone and 850 mg metformin

Peeline M Related Warnings

  • Is the use of Peeline M safe for pregnant women?


    Peeline M may have some side effects during pregnancy. Pregnant women should discontinue the use of Peeline M, and talk to their doctor, if they notice any discomfort.

  • Is the use of Peeline M safe during breastfeeding?


    If you are breastfeeding, you may experience some harmful effects of Peeline M. In case you experience any of these, discontinue its use until you consult your doctor.

  • What is the effect of Peeline M on the Kidneys?


    Peeline M rarely affects the kidneys.

  • What is the effect of Peeline M on the Liver?


    Peeline M can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

  • What is the effect of Peeline M on the Heart?


    Peeline M can have moderate side effects on the heart. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.



Severe Interaction of Peeline M with Other Drugs

Peeline M should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Peeline M Contraindications

If you are suffering from any of the following diseases, you should not take Peeline M unless your doctor advises you to do so -



Frequently asked Questions about Peeline M

  • Is this Peeline M habit forming or addictive?


    Peeline M does not cause addiction.

Peeline M Interactions with Food and Alcohol

  • Interaction between Food and Peeline M


    Information is not available on the interaction of any foods with Peeline M, due to a lack of research on this.

  • Interaction between Alcohol and Peeline M


    Taking [medicine] and alcohol at the same time may lead to mild side effects. Contact your doctor right away if you observe any side effects.



Frequently asked Questions about Peeline M

Question over 4 years ago

How does Peeline M work for PCOS?

Dr. Sameer Awadhiya MBBS , Pediatrics

Peeline M increases the sensitivity of insulin, young women with PCOS often have elevated insulin levels and are more likely to develop diabetes. It is often prescribed for women with PCOS to help prevent diabetes. A lifestyle that includes healthy nutrition and daily exercise is the most important part of a PCOS treatment plan.

Question over 4 years ago

How does Peeline M increase lactic acidosis?

Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with Peeline M treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Peeline M induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst. 

Question about 5 years ago

How does Peeline M help in weight loss?

Dr. Sameer Awadhiya MBBS , Pediatrics

Peeline M helps in weight loss by reducing appetite and food intake. It also increases the insulin sensitivity in your body to work more effectively. This lead to decreased glucose production increases the use of glucose and decrease the fat deposition further helps in weight loss. However, Peeline M is not approved for weight loss, this is an off-label use.

Question over 4 years ago

Can I take Peeline M with a beta-blocker?

Dr. Sameer Awadhiya MBBS , Pediatrics

Yes, you can take Peeline M with a beta-blocker. People with diabetes tend to develop heart disease or stroke at an earlier age than the general population. One reason for this is that high glucose levels increase your risk of high blood pressure (hypertension). No harmful interactions are seen between them. However, a recent study suggests that beta-blockers can decrease the plasma level of Peeline M and long-term use can increase lactic acid and uric acid in the blood.

Question over 4 years ago

Does Peeline M cause stomach ulcers?

Dr. Mayank Yadav MBBS , General Physician

Yes, Peeline M commonly cause stomach upset like diarrhea, abdominal pain, nausea, and vomiting. To avoid these side effects you should take Peeline M with your meal and increase the dose gradually.



See all substitutes for Peeline M


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glucophage® (metformin hydrochloride)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275-276

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 825-826

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Actos (pioglitazone hydrochloride)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 276-277

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1032-1033

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