Topirate

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Topirate Information

Topirate is a prescription medicine that is available as a Tablet. Epilepsy are some of its major therapeutic uses. Secondary and off-label uses of Topirate have also been mentioned below.

The right dosage of Topirate depends on the age, gender, and medical history of the patient. Individual symptoms and route of administration also determines the right dosage. Detailed information has been provided in the dosage section.

Besides the aforementioned side effects, there are other adverse effects of Topirate as well, which are listed below. These side effects of Topirate are usually temporary and subside with the completion of treatment. Consult your doctor if these side effects become worse or stay for a longer duration.

Topirate's effect during pregnancy is Moderate and Mild while nursing. Further, the section on Topirate related warnings talks about Topirate's effects on the liver, heart and kidney.

Topirate can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Topirate in conditions like Suicidal Tendency, Liver Disease. Some other conditions that can be affected by Topirate are listed in the contraindications section below.

Drug interactions for Topirate have been reported in the medical literature. See below for a complete list.

In addition to these precautions, you may also note that Topirate is not safe while driving, and is is not addictive in nature.



Topirate Benefits & Uses

Topirate is used to treat the following -

Main Benefits

Other Benefits

Topirate Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Migraine
  • Before or After Meal: Either
  • Single Maximum Dose: 25 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: gradually increases upto 50 mg twice daily
Geriatric
  • Disease: Migraine
  • Before or After Meal: Either
  • Single Maximum Dose: 25 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: gradually increases upto 50 mg twice daily
13 - 18 years (Adolescent)
  • Disease: Migraine
  • Before or After Meal: Either
  • Single Maximum Dose: 25 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: gradually increases upto 50 mg twice daily
2 - 12 years (Child)
  • Disease: Epilepsy
  • Before or After Meal: Either
  • Single Maximum Dose: 25 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: gradually increases upto 350 mg/day

Topirate Related Warnings

  • Is the use of Topirate safe for pregnant women?


    Topirate can have harmful effects in pregnant women. If you experience any discomfort after using Topirate, then discontinue the use and take your doctor's advice.

    Moderate
  • Is the use of Topirate safe during breastfeeding?


    Side effects of Topirate for breastfeeding are little to none, so you can take it without doctor's advice.

    Mild
  • What is the effect of Topirate on the Kidneys?


    Very few cases of side effects of Topirate on kidney have been reported.

    Mild
  • What is the effect of Topirate on the Liver?


    Topirate is rarely harmful for the liver.

    Mild
  • What is the effect of Topirate on the Heart?


    Topirate is completely safe for the heart.

    Safe


Severe Interaction of Topirate with Other Drugs

Topirate should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate



Topirate Contraindications

If you are suffering from any of the following diseases, you should not take Topirate unless your doctor advises you to do so -



Frequently asked Questions about Topirate

  • Is this Topirate habit forming or addictive?


    No, you will not get addicted to Topirate.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Topirate you may feel sleepy. So it is not advised to perform these activities.

    Dangerous
  • Is it safe?


    Yes, but take Topirate only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Yes, taking Topirate can treat mental disorders.

    Yes

Topirate Interactions with Food and Alcohol

  • Interaction between Food and Topirate


    It is safe to take Topirate with food.

    Safe
  • Interaction between Alcohol and Topirate


    Taking Topirate with alcohol can have severely harmful effects on your health.

    Severe


See all substitutes for Topirate


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1018-1019

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 420

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Topamax® (topiramate)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Trokendi XR (topiramate)



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