Digoxin

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  • Contains / Salt: Digoxin (0.25 mg)
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Digoxin Information

Digoxin is a prescription drug, available for use as Injection,Tablet,Liquid. Primarily, it is used for the treatment of Heart Failure, Arrhythmia. Digoxin also has some secondary and off-label uses. These are listed below.

The right dosage of Digoxin depends on the age, gender, and medical history of the patient. Individual symptoms and route of administration also determines the right dosage. Refer to the dosage section for a detailed discussion.

Apart from the aforementioned side effects, Digoxin can also lead to other problems, which have been listed below. Usually, these side effects of Digoxin go away soon, and do not persist beyond the duration of the treatment. If, however, they worsen or do not go away, please speak with your physician.

In addition, Digoxin's effect is Severe during pregnancy and Safe for lactating mothers. Further, the section on Digoxin related warnings talks about Digoxin's effects on the liver, heart and kidney.

Individuals suffering from medical conditions like Bradycardia (Slow Heart Rate), Hypercalcemia must refrain from the use of Digoxin since this can cause severe adverse effects. Other contraindications of Digoxin have been discussed in the sections ahead.

Besides this, Digoxin may also have severe interaction with some medicines. Refer to the list below for further details.

Along with the above-mentioned precautions, remember that taking Digoxin is considered not safe while driving, and is not addictive.



Digoxin Benefits & Uses

Digoxin is used to treat the following -

Main Benefits

Other Benefits

Digoxin Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Heart Failure
  • Before or After Meal: Either
  • Single Maximum Dose: 0.25 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice, dose may rarely increase 0.375-0.5 mg/day
Geriatric
  • Disease: Heart Failure
  • Before or After Meal: Either
  • Single Maximum Dose: 0.25 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice, dose may rarely increase 0.375-0.5 mg/day
13 - 18 years (Adolescent)
  • Disease: Heart Failure
  • Before or After Meal: Either
  • Single Maximum Dose: 5 mcg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice
2 - 12 years (Child)
  • Disease: Heart Failure
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 5 mcg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: For course duration follow doctor's advice, Initially given 17.5 mcg/kg for 3 dose

Digoxin Related Warnings

  • Is the use of Digoxin safe for pregnant women?


    Digoxin should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.

    Severe
  • Is the use of Digoxin safe during breastfeeding?


    Breastfeeding women can safely use Digoxin.

    Safe
  • What is the effect of Digoxin on the Kidneys?


    Digoxin rarely affects the kidneys.

    Mild
  • What is the effect of Digoxin on the Liver?


    Information about safety of Digoxin for the liver is not available since scientific research on this is yet to be done.

    Unknown
  • What is the effect of Digoxin on the Heart?


    Digoxin is rarely harmful for the heart.

    Mild


Severe Interaction of Digoxin with Other Drugs

Digoxin should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Digoxin Contraindications

If you are suffering from any of the following diseases, you should not take Digoxin unless your doctor advises you to do so -



Frequently asked Questions about Digoxin

  • Is this Digoxin habit forming or addictive?


    Forming a habit of Digoxin has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should do not do anything that requires concentration and attention as the Digoxin can make you feel drowsy.

    Dangerous
  • Is it safe?


    Digoxin should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Digoxin for mental disorders.

    No

Digoxin Interactions with Food and Alcohol

  • Interaction between Food and Digoxin


    Taking Digoxin with food is safe.

    Safe
  • Interaction between Alcohol and Digoxin


    Information about the interaction of Digoxin and alcohol is not currently available because this topic has not been researched yet.

    Unknown


Frequently asked Questions about Digoxin

Question almost 5 years ago

Can Digoxin cause weight loss?

Dr. OP Kholwad MBBS , General Physician

Yes, Digoxin can cause weight loss if it is taken in higher doses. Weight loss occurs especially in children and older age group (Geriatric). However, if you are experiencing rapid weight loss then discuss it with your doctor instantly.

Question almost 5 years ago

Does Digoxin cause constipation?

Dr. Kapil Sharma MBBS , General Physician

No, Digoxin does not cause constipation. However, if you are experiencing constipation after taking this drug, it may be due to some other medical conditions. Take precautionary methods if you suffer from constipation such as eating fibrous food, drink plenty of fluid, and take some laxative (Lactulose syrup).

Question about 5 years ago

How to take Digoxin?

Dr. B. K. Agrawal MBBS, MD , Cardiology, General Physician, Internal Medicine

Take Digoxin once daily or as advised by your doctor. It can be taken with or without food. Precautions must be taken in patients with hypertension, heart block, and improper kidney function.

Question almost 5 years ago

Can I take Digoxin without consulting a doctor?

Dr. Kuldeep Meena MBBS, MD , Cardiology, Neurology, Pediatrics, Dermatology, Pulmonology, Nephrology, General Physician, Other, Infectious Disease, Emergency Medicine, Allergy and Immunology, Internal Medicine, Multispeciality

No, Digoxin is a high alert and prescription drug so do not take it without consulting a doctor. It can be harmful to the patient to take this medicine without a doctor's recommendation because it can cause very unpleasant side effects. Hence, you should always consult a doctor before taking this medication by himself or herself.

Question over 4 years ago

Can I take metoprolol and Digoxin together?

Dr. Abhijit MBBS , General Physician

Avoid taking metoprolol and Digoxin together. Because metoprolol might slow the heart rate and increase the chances of side effects. However, if your doctor advises you to take both of these drugs at the same time then you can take them together.



See all substitutes for Digoxin


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 430-433

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 512-519

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Lanoxin® (digoxin)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Sigmaxin (digoxin)

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