Glyrep

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10 Tablet in 1 Strip Out of Stock
₹ 15
10 TABLET 1 Strip ₹ 15
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  • Contains / Salt: Metformin (500 mg)
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Glyrep Information

Glyrep is a prescription drug, available for use as Tablet. It is typically used for the treatment of Diabetes.

The optimal dosage of Glyrep is largely dependent on the individual's body weight, medical history, gender and age. The condition it has been prescribed for, and the route of administration also determine the right dosage. Detailed information has been provided in the dosage section.

The most common side effects of Glyrep are Stomach Upset, Difficulty urinating. Apart from the aforementioned side effects, Glyrep can also lead to other problems, which have been listed below. These side effects of Glyrep are usually temporary and subside with the completion of treatment. Consult your doctor if these side effects become worse or stay for a longer duration.

Glyrep's effect during pregnancy is Mild and Moderate while nursing. In addition, Glyrep's effects on the liver, heart and kidney are discussed below in the Glyrep related warnings section.

Glyrep is contraindicated in people with pre-existing medical conditions like Congestive Heart Failure (CHF), Anemia, Shock as it can result in adverse effects. The section on Glyrep contraindications lists all such conditions.

Besides this, Glyrep may also have severe interaction with some medicines. See below for a complete list.

Along with the above-mentioned precautions, remember that taking Glyrep is considered safe while driving, and is addictive.



Glyrep Benefits & Uses

Glyrep is used to treat the following -

Main Benefits

Glyrep Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 500 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 500 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 500 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 500 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor


Glyrep Side Effects

Based on research, the following side effects have been observed when Glyrep is used -

Severe

  • Blurred vision

Moderate

Mild

  • Nausea or vomiting
  • Altered taste
  • Diarrhoea
  • पेट दर्द
  • Loss of appetite
  • Headache
  • पेट की गैस
  • Dyspepsia

Common

  • Stomach Upset
  • Difficulty urinating

Glyrep Related Warnings

  • Is the use of Glyrep safe for pregnant women?


    Pregnant women may get mild side effects from Glyrep.

    Mild
  • Is the use of Glyrep safe during breastfeeding?


    Breastfeeding women may feel side effects of Glyrep. If you see any side effects, stop taking Glyrep immediately and talk to your doctor. Take Glyrep again, only after your doctor's advice.

    Moderate
  • What is the effect of Glyrep on the Kidneys?


    Glyrep does not damage the kidneys.

    Safe
  • What is the effect of Glyrep on the Liver?


    Glyrep is completely safe for the liver.

    Safe
  • What is the effect of Glyrep on the Heart?


    Glyrep is completely safe for the heart.

    Safe


Severe Interaction of Glyrep with Other Drugs

Glyrep should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Glyrep Contraindications

If you are suffering from any of the following diseases, you should not take Glyrep unless your doctor advises you to do so -



Frequently asked Questions about Glyrep

  • Is this Glyrep habit forming or addictive?


    No, there is no any evidence that Glyrep is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can comfortably use machinery or drive after taking Glyrep since it will not make you feel sleepy.

    Safe
  • Is it safe?


    Glyrep should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Glyrep in mental disorders is not effective.

    No

Glyrep Interactions with Food and Alcohol

  • Interaction between Food and Glyrep


    Due to a lack of research, nothing can be said about the consequences of taking Glyrep together with food.

    Unknown
  • Interaction between Alcohol and Glyrep


    Taking alcohol with Glyrep can be dangerous.

    Severe


Frequently asked Questions about Glyrep

Question over 4 years ago

Does Glyrep cause low blood sugar (hypoglycemia)?

Dr. Ramraj MBBS , Other

Yes, Glyrep can cause low blood sugar (hypoglycemia). However, this can also occur if you delay or miss a meal, drink alcohol, exercise more than usual, can't eat due to stomach upset, and taking other antidiabetic medicine with metformin. So, regular monitoring of blood glucose level is needed and be cautious of symptoms of hypoglycemia, always keep glucose-rich food with you. 

Question almost 5 years ago

Does Glyrep cause sleep problems?

Dr. Ayush Pandey MBBS, PG Diploma , General Physician

Yes, Glyrep can cause some sleep problems, especially insomnia. On the other hand, Glyrep has proven to be useful for preventing sleep apnea. The exact relationship between Glyrep and sleep problems is still not clear, and further studies are needed for a clearer understanding.

Question over 4 years ago

How does Glyrep work for PCOS?

Dr. Sameer Awadhiya MBBS , Pediatrics

Glyrep increases the sensitivity of insulin, young women with PCOS often have elevated insulin levels and are more likely to develop diabetes. It is often prescribed for women with PCOS to help prevent diabetes. A lifestyle that includes healthy nutrition and daily exercise is the most important part of a PCOS treatment plan.

Question almost 5 years ago

Can I take Glyrep with statin?

Dr. R.K Singh MBBS , Diabetology

Yes, Glyrep can be taken with the statin. There is no serious or harmful interaction have been observed between them. Some studies say that it's possible your blood sugar (blood glucose) level may increase when you take a statin, which may lead to developing type 2 diabetes. The risk is small but important enough that the Food and Drug Administration (FDA) has issued a warning on statin labels regarding blood glucose levels and diabetes.

Question over 4 years ago

How does Glyrep increase lactic acidosis?

Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with Glyrep treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Glyrep induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst. 



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This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glucophage® (metformin hydrochloride)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275-276

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 825-826

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