Mesna(Zydus) Information

Mesna(Zydus) is a prescription drug, available for use as Injection. Hemorrhagic Cystitis are some of its major therapeutic uses.

The right dosage of Mesna(Zydus) depends on the age, gender, and medical history of the patient. Individual symptoms and route of administration also determines the right dosage. This information has been provided in detail in the dosage section.

The most common side effects of Mesna(Zydus) are Lightheadedness. While these are the most often observed Mesna(Zydus) side effects, there are can be others also. These have been listed below. Such side effects of Mesna(Zydus) normally do not last long and go away once the treatment is completed. Please speak with your doctor if these side effects worsen or persist for a longer duration.

Furthermore, you should know that effect of Mesna(Zydus) is Safe for pregnant women and Moderate for women who are breastfeeding. It is important to know if Mesna(Zydus) has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Mesna(Zydus) related warnings section.

Other conditions have been mentioned below in the Mesna(Zydus) contraindications section.

Besides this, Mesna(Zydus) may also have severe interaction with some medicines. See below for a complete list.

In addition to the above precautions for Mesna(Zydus), it is important to know that it is not safe while driving, and is not habit-forming.

Mesna(Zydus) Benefits & Uses
Mesna(Zydus) Dosage & How to Take
Mesna(Zydus) Side Effects
Mesna(Zydus) Related Warnings
Severe Interaction of Mesna(Zydus) with Other Drugs
Mesna(Zydus) Contraindications
Frequently asked Questions about Mesna(Zydus)
Mesna(Zydus) Interactions with Food and Alcohol

Mesna(Zydus) Benefits & Uses

Mesna(Zydus) is used to treat the following -

Main Benefits

Hemorrhagic Cystitis

Mesna(Zydus) Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Hemorrhagic Cystitis Before or After Meal: As advised by a physician Single Maximum Dose: 200 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: hemorrhagic cystitis induced by ifosfamide or cyclophosphamide, dosage of mesna at least 20% (w/w) of the ifosfamide dosage
Geriatric	Disease: Hemorrhagic Cystitis Before or After Meal: As advised by a physician Single Maximum Dose: 200 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: hemorrhagic cystitis induced by ifosfamide or cyclophosphamide, dosage of mesna at least 20% (w/w) of the ifosfamide dosage

Mesna(Zydus) Side Effects

Based on research, the following side effects have been observed when Mesna(Zydus) is used -

Moderate

Constipation (Read More - Home remedies for constipation)
Chest Pain
Peripheral Edema

Mild

Nausea or vomiting
Headache
पेट दर्द
Flushing
Diarrhoea
Fever (Read More - Home remedies for fever)
Fatigue
Insomnia
Loss of appetite
Drowsiness

Common

Lightheadedness

Mesna(Zydus) Related Warnings

Is the use of Mesna(Zydus) safe for pregnant women?

Pregnant women can take Mesna(Zydus) without worrying about any side effects.

Safe
Is the use of Mesna(Zydus) safe during breastfeeding?

If you are breastfeeding, you may experience some harmful effects of Mesna(Zydus). In case you experience any of these, discontinue its use until you consult your doctor.

Moderate
What is the effect of Mesna(Zydus) on the Kidneys?

Mesna(Zydus) is not harmful for kidneys.

Safe
What is the effect of Mesna(Zydus) on the Liver?

Mesna(Zydus) is completely safe for the liver.

Safe
What is the effect of Mesna(Zydus) on the Heart?

Mesna(Zydus) is not harmful for the heart.

Safe

Severe Interaction of Mesna(Zydus) with Other Drugs

Mesna(Zydus) should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate

Warfarin

Mesna(Zydus) Contraindications

If you are suffering from any of the following diseases, you should not take Mesna(Zydus) unless your doctor advises you to do so -

Rheumatoid Arthritis

Frequently asked Questions about Mesna(Zydus)

Is this Mesna(Zydus) habit forming or addictive?

No, you will not get addicted to Mesna(Zydus).

No
Is it safe to drive or operate heavy machinery when consuming?

No, you should not drive or operate heavy machinery after taking Mesna(Zydus) as you may feel sleepy.

Dangerous
Is it safe?

Mesna(Zydus) should be used only after doctor's advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, the use of Mesna(Zydus) in mental disorders is not effective.

No

Mesna(Zydus) Interactions with Food and Alcohol

Interaction between Food and Mesna(Zydus)

Due to the absence of research, it is difficult to say how Mesna(Zydus) and food will interact.

Unknown
Interaction between Alcohol and Mesna(Zydus)

Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Mesna(Zydus).

Unknown

See all substitutes for Mesna(Zydus)

Mesna Injection - ₹33
Mesolit Injection - ₹89
Mistabron 200 Respirator Solution - ₹204
Mistabron 600 Respirator Solution - ₹185
Uromitexan Injection - ₹103
Mesna Injection - ₹103

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Mesnex (mesna)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 860, 876

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 822-824

Mesna(Zydus)