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Indomethacin is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
Based on research, the following side effects have been observed when Indomethacin is used -
Moderate
Mild
Is the use of Indomethacin safe for pregnant women?
Indomethacin shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.
Is the use of Indomethacin safe during breastfeeding?
Women who are breastfeeding may experience severe harmful effects after taking Indomethacin. It should only be taken after medical advice.
What is the effect of Indomethacin on the Kidneys?
Effects of Indomethacin on kidney can be severe. It is not safe to use it without doctor's advice.
What is the effect of Indomethacin on the Liver?
Use of Indomethacin may be dangerous for the liver. Do not use it without doctor's advice.
What is the effect of Indomethacin on the Heart?
You may experience side effects on your heart after taking Indomethacin. If this happens, then discontinue its use. Consult your medical practitioner, and do as he/she suggests.
Indomethacin should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Indomethacin unless your doctor advises you to do so -
Is this Indomethacin habit forming or addictive?
Indomethacin is not addictive in nature.
Is it safe to drive or operate heavy machinery when consuming?
Indomethacin will not make you feel sleepy or drowsy. So you drive or operate machinery safely.
Is it safe?
Indomethacin is safe but it is important to consult a doctor before taking it.
Is it able to treat mental disorders?
Indomethacin is unable to treat or cure mental disorders.
Interaction between Food and Indomethacin
There isn't any research available on the side effects of taking Indomethacin with food.
Interaction between Alcohol and Indomethacin
Taking Indomethacin with alcohol can have severely harmful effects on your health.
Yes, Indomethacin can cause weight fluctuations (weight gain or loss). It is uncommon side effects of this drug and it occurs only in few cases. If you are experiencing rapid weight fluctuation after taking this drug then please inform your doctor and follow his/her instructions.
Yes, Indomethacin can cause stomach problems such as nausea, vomiting, and stomach pain. Please inform your doctor if you are experiencing these symptoms after taking this drug.
Yes, Indomethacin can increase blood pressure (BP) in some people, if taken a high dose. It may increase the chance of stroke and heart attack. Your healthcare practitioner will regularly monitor your blood pressure from time to time, to make sure that it is safe to use for your condition.
Indomethacin is presumed to work by blocking the synthesis of prostaglandins through inhibition of enzymes (cyclooxygenase-1 and -2 also known as COX-1 and -2) which is responsible for inflammation (swelling) in our body. This helps in effectively providing relief to the patient from and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
Yes, Indomethacin is safe to use, if taken in a prescribed amount for a specified time as advised by the doctor. However, few side effects are observed such as difficulty in breathing, intestinal bleeding, and swelling of the face, lips, tongue or throat. Do not hesitate to inform your doctor if you are facing any of the above.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 682-684
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 202
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Indocin SR (indomethacin)
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Indocin® I.V. (indomethacin)
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Indocin® (indomethacin)