Temozolomide



  • Manufactured by:
  • Contains / Salt: Temozolomide


Temozolomide Information



Temozolomide Benefits & Uses

Temozolomide is used to treat the following -

Other Benefits

Temozolomide Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Brain Tumour
  • Before or After Meal: Either
  • Single Maximum Dose: 125 mg
  • Dosage Form: Capsule
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 7 weeks
  • Special Instructions: Given 75 mg/m2 orally once a day, Concomitant phase with focal radiotherapy
Geriatric
  • Disease: Brain Tumour
  • Before or After Meal: Either
  • Single Maximum Dose: 125 mg
  • Dosage Form: Capsule
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 7 weeks
  • Special Instructions: Given 75 mg/m2 orally once a day, Concomitant phase with focal radiotherapy
13 - 18 years (Adolescent)
  • Disease: Anaplastic Astrocytoma
  • Before or After Meal: Either
  • Single Maximum Dose: 200 mg
  • Dosage Form: Capsule
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 5 days
  • Special Instructions: First 5 days of each treatment cycle, 150 mg/meter square
2 - 12 years (Child)
  • Disease: Anaplastic Astrocytoma
  • Before or After Meal: Either
  • Single Maximum Dose: 120 mg
  • Dosage Form: Capsule
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 5 days
  • Special Instructions: First 5 days of each treatment cycle, 150 mg/meter square, dose 3 years and older children


Temozolomide Side Effects

Based on research, the following side effects have been observed when Temozolomide is used -

Severe

Moderate

  • Rash

Mild

Temozolomide Related Warnings

  • Is the use of Temozolomide safe for pregnant women?


    Pregnant women may get severe side effects after taking Temozolomide. If you are pregnant, do not take Temozolomide without a doctor's advice.

    Severe
  • Is the use of Temozolomide safe during breastfeeding?


    Women who are breastfeeding, may experience serious side effects after taking Temozolomide. So it is adviced to consult the doctor before using it.

    Severe
  • What is the effect of Temozolomide on the Kidneys?


    Temozolomide rarely affects the kidneys.

    Mild
  • What is the effect of Temozolomide on the Liver?


    Very few cases of side effects of Temozolomide on the liver have been reported.

    Mild
  • What is the effect of Temozolomide on the Heart?


    Temozolomide may have mild side effects on the heart. Most people will never see any effect on the heart.

    Mild


Severe Interaction of Temozolomide with Other Drugs

Temozolomide should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Temozolomide Contraindications

If you are suffering from any of the following diseases, you should not take Temozolomide unless your doctor advises you to do so -



Frequently asked Questions about Temozolomide

  • Is this Temozolomide habit forming or addictive?


    Temozolomide does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Temozolomide, you should not drive or work on any heavy machine, as Temozolomide can make you drowsy.

    Dangerous
  • Is it safe?


    Yes, but consume Temozolomide only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Temozolomide is unable to treat or cure mental disorders.

    No

Temozolomide Interactions with Food and Alcohol

  • Interaction between Food and Temozolomide


    It is safe to take Temozolomide with food.

    Safe
  • Interaction between Alcohol and Temozolomide


    Information about the interaction of Temozolomide and alcohol is not currently available because this topic has not been researched yet.

    Unknown


See all substitutes for Temozolomide


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Temodar® (temozolomide)



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