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What is fatigue?

Fatigue is an overpowering and extreme tiredness that may not be relieved by rest. Fatigue due to illnesses, overexertion or disturbance in sleep, diet or routine activities lasts for less than 6 months and generally improves with rest. Chronic fatigue occurs without a definite cause and continues for more than 6 months. A psychological disturbance is frequently associated with fatigue or chronic fatigue syndrome.

What are its main associated signs and symptoms?

Amidst the numerous signs and symptoms associated with fatigue, some of the most important ones are as follows:

  • Fatigue is an important symptom of chronic fatigue syndrome or myalgic encephalomyelitis (ME) and is characterised by:
    • Significant decrease in capacity to carry out daily activities which were possible before the onset of fatigue.
    • Extreme exhaustion after routine activities that was not experienced before ME.
    • No relief in fatigue after rest and sleep.
    • Increase in tiredness and other symptoms that may last for days after a mental or physical activity.
  • Problems with memory and thinking, difficulty with concentration and increased emotional sensitivity
  • Disorder in sleep pattern (excessive sleep, lack of sleep, disturbed sleep)
  • Headache, dizziness and blurred vision
  • Lack of energy, with muscle and joint pain
  • Frequent sore throat
  • Disturbances in digestion (Read more: Indigestion treatment)
  • Flu-like symptoms
  • Lymph nodes may be painful and tender

What are its main causes?

The different causes attributed to fatigue include:

How is it diagnosed and treated?

Doctors order various laboratory tests and other investigations to rule out different causes of fatigue. History and physical examination play an important role in diagnosing fatigue without any definite cause.

  • History regarding:
    • Onset and duration of symptoms
    • Daily routine, triggers, previous diseases and treatments, etc.
  • Physical examination includes:
    • Examination of lymph nodes and checking for swelling of feet
    • Chest examination for abnormality in heartbeats and breathing trouble
    • Examination of the nervous system and the thyroid gland
  • Investigations and lab tests include:
    • Blood test: Complete blood count (CBC), erythrocyte sedimentation rate (ESR) and thyroid profile
    • Urine tests
    • X-ray chest and electrocardiogram (ECG)
  • Other special tests are done depending on the cause of fatigue

Treatment comprises:

  • Treatment of the cause responsible for fatigue
    • Medicines for cancer, infections, depression, thyroid problems, etc.
  • Management of symptoms through
    • Regular moderate exercise
    • Dividing the task into small units
    • Taking frequent breaks while working
    • Undertaking smaller tasks at a time
    • Meditation and yoga
    • Adequate rest and sleep
  1. Medicines for Fatigue
  2. Doctors for Fatigue
Dr. Gaurav Chauhan

Dr. Gaurav Chauhan

सामान्य चिकित्सा

Dr. Sushila Kataria

Dr. Sushila Kataria

सामान्य चिकित्सा

Dr. Sanjay Mittal

Dr. Sanjay Mittal

सामान्य चिकित्सा

Medicines for Fatigue

Medicines listed below are available for Fatigue. Please note that you should not take any medicines without doctor consultation. Taking any medicine without doctor's consultation can cause serious problems.

Medicine NamePack SizePrice (Rs.)
VasograinVasograin Tablet75
SaridonSaridon Tablet27
NeuroxetinNeuroxetin 20 Mg/0.5 Mg Capsule37
ADEL 28 Plevent DropADEL 28 Plevent Drop200
Schwabe Lathyrus sativus CHSchwabe Lathyrus sativus 1000 CH96
Rejunuron DlRejunuron Dl 30 Mg/750 Mg Capsule52
ADEL 29 Akutur DropADEL 29 Akutur Drop200
SBL Selenium DilutionSBL Selenium Dilution 1000 CH86
Dulane MDulane M 20 Mg/1.5 Mg Tablet81
SBL Arnica Montana Hair Oil Arnica Montana Hair Oil56
Schwabe Sabal PentarkanSchwabe Sabal Pentarkan 128
Dumore MDumore M Capsule103
ADEL 31 Upelva DropADEL 31 Upelva Drop200
DuotopDuotop 20 Mg/1.5 Mg Tablet46
Schwabe Silicea TabletSchwabe Silicea Biochemic Tablet 200X560
Duvanta ForteDuvanta Forte Capsule66
Schwabe Aletris farinosa MTSchwabe Aletris farinosa MT 388
Duvanta NpDuvanta Np 20 Mg/500 Mcg Tablet38
ADEL 34 Ailgeno DropADEL 34 Ailgeno Drop200
Duxet MDuxet M 20 Mg/1500 Mcg Capsule54
ADEL 36 Pollon DropADEL 36 Pollon Drop200
Duzela MDuzela M 20 Mg/1.5 Mg Tablet81
Bjain Silicea LMBjain Silicea 0/1 LM39
Nerv DxNerv Dx Capsule43

Do you or anyone in your family have this disease? Please do a survey and help others


  1. American Academy of Family Physicians [Internet]. Leawood (KS); Fatigue: An Overview
  2. Center for Disease Control and Prevention [internet], Atlanta (GA): US Department of Health and Human Services; Symptoms of ME/CFS
  3. NHS Inform. Coping with fatigue. National health information service, Scotland. [internet].
  4. NHS Inform. Chronic fatigue syndrome (CFS). National health information service, Scotland. [internet].
  5. Better health channel. Department of Health and Human Services [internet]. State government of Victoria; Fatigue
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