Amitril Plus

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  • Manufactured by: Sigmund Promedica
  • Contains / Salt: Amitriptyline (12.5 mg) + Chlordiazepoxide (5 mg)

Amitril Plus Information

Amitril Plus is a prescription drug, available for use as Tablet. Primarily, it is used for the treatment of Depression, Anxiety.

Medical history of the patient along with age and gender determines the dosage of Amitril Plus. Individual symptoms and route of administration also determines the right dosage. Detailed information has been provided in the dosage section.

The most common side effects of Amitril Plus are Drowsiness, Dizziness, Bloating or fullness. Besides the aforementioned side effects, there are other adverse effects of Amitril Plus as well, which are listed below. These side effects of Amitril Plus are usually temporary and subside with the completion of treatment. Consult your doctor if these side effects become worse or stay for a longer duration.

In addition, Amitril Plus's effect is Moderate during pregnancy and Moderate for lactating mothers. It is important to know if Amitril Plus has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Amitril Plus related warnings section.

Amitril Plus is contraindicated in people with pre-existing medical conditions like Suicidal Tendency as it can result in adverse effects. Some other conditions that can be affected by Amitril Plus are listed in the contraindications section below.

Besides this, Amitril Plus may also have severe interaction with some medicines. See below for a complete list.

Along with the above-mentioned precautions, remember that taking Amitril Plus is considered not safe while driving, and is not addictive.


Amitril Plus Benefits & Uses

Amitril Plus is used to treat the following -

Amitril Plus Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease:
  • Before or After Meal: Either
  • Single Maximum Dose: 1 Tablet
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 4 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: strength 25 mg amitriptyline and 10 mg chlordiazepoxide
Geriatric
  • Disease:
  • Before or After Meal: Either
  • Single Maximum Dose: 1 Tablet
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 4 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: strength 25 mg amitriptyline and 10 mg chlordiazepoxide

Amitril Plus Side Effects

Based on research, the following side effects have been observed when Amitril Plus is used -

Mild

  • Tremor
  • Confusion
  • Weakness

Common

Amitril Plus Related Warnings

  • Is the use of Amitril Plus safe for pregnant women?


    Amitril Plus can cause unwanted side effects in pregnant women. If you experience any side effects, stop taking Amitril Plus right away. Take your doctor's advice before taking it again.

    Moderate
  • Is the use of Amitril Plus safe during breastfeeding?


    If you are breastfeeding, you may experience some harmful effects of Amitril Plus. In case you experience any of these, discontinue its use until you consult your doctor.

    Moderate
  • What is the effect of Amitril Plus on the Kidneys?


    Very few cases of side effects of Amitril Plus on kidney have been reported.

    Mild
  • What is the effect of Amitril Plus on the Liver?


    Very few cases of side effects of Amitril Plus on the liver have been reported.

    Mild
  • What is the effect of Amitril Plus on the Heart?


    Side effects of Amitril Plus rarely affect the heart.

    Mild

Severe Interaction of Amitril Plus with Other Drugs

Amitril Plus should not be taken with following medicines due to severe side effects it may cause to patients -

Severe


Amitril Plus Contraindications

If you are suffering from any of the following diseases, you should not take Amitril Plus unless your doctor advises you to do so -


Frequently asked Questions about Amitril Plus

  • Is this Amitril Plus habit forming or addictive?


    Yes, Amitril Plus can get addictive. Consume it only after doctor's advise.

    Yes
  • Is it safe to drive or operate heavy machinery when consuming?


    You may feel sleepy or tired after taking Amitril Plus. So it is best to avoid driving.

    Dangerous
  • Is it safe?


    Amitril Plus is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Yes, in many cases, taking Amitril Plus can help with mental disorders.

    Yes

Amitril Plus Interactions with Food and Alcohol

  • Interaction between Food and Amitril Plus


    It is safe to take Amitril Plus with food.

    Safe
  • Interaction between Alcohol and Amitril Plus


    Consult your doctor before consuming alcohol while taking Amitril Plus as it can have severe side effects.

    Severe

Frequently asked Questions about Amitril Plus

Question over 6 years ago

Does Amitril Plus cause dry mouth?

Dr. Roshni Poonja MBBS , General Physician, Internal Medicine

Yes, Amitril Plus can cause dry mouth. It is a common side effect of it. If you experience excess dry mouth after taking this drug, please consult your doctor and follow his/her instructions.

Question over 6 years ago

Can I take Amitril Plus With Paracetamol?

Dr. Ram Saini MD, MBBS , General Physician

Yes, Amitril Plus can be taken with paracetamol. No harmful interactions have been reported between them. However, if you feel any discomfort after taking these two medicines together, please consult your doctor. 

Question over 7 years ago

What is Amitril Plus?

Dr. Uday Nath Sahoo MBBS , Internal Medicine

Amitril Plus is a brand name of amitriptyline. It is a prescription drug that belongs to the class of medications called tricyclic antidepressant. It is used primarily for treating symptoms of depression, anxiety, and tension. This medicine also helps in inducing sleep. Amitril Plus is also prescribed to get relieved from neuropathic pain.

Question over 6 years ago

Can I take Amitril Plus with antihistamine?

Dr. Ramraj MBBS , Other

Using Amitril Plus together with antihistamines may increase unpleasant drug-induced side effects such as dizziness, drowsiness, and difficulty in breathing. Avoid taking these medicines together or consult your doctor before taking these two medicine at the same time.

Question over 6 years ago

Can I take Amitril Plus for anxiety?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

Yes, Amitril Plus can be taken for anxiety. However, you are recommended to seek medical advice and choose the right treatment for anxiety. Do not continue taking this medicine endlessly without doctor consultation.


See all substitutes for Amitril Plus


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
7 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Amitriptyline Hydrochloride

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 454,458

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 145-147

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Librium® C-IV (chlordiazepoxide HCl)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 401-403

Package Leaflet [Internet]: LIBRIUM. Labiana Pharmaceuticals

Product Description [Internet]: LIMBITROL®. USFDA

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