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Chloramphenicol + Dexamethasone + Polymyxin B is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
13 - 18 years (Adolescent) |
|
2 - 12 years (Child) |
|
Adult |
|
Geriatric |
|
Is the use of Chloramphenicol + Dexamethasone + Polymyxin B safe for pregnant women?
The effects of Chloramphenicol + Dexamethasone + Polymyxin B on pregnant women are unknown since no research has been done to ascertain it yet.
Is the use of Chloramphenicol + Dexamethasone + Polymyxin B safe during breastfeeding?
In the absence of any scientific study about the side effects of Chloramphenicol + Dexamethasone + Polymyxin B in breastfeeding women, information on safety of Chloramphenicol + Dexamethasone + Polymyxin B is unavailable.
What is the effect of Chloramphenicol + Dexamethasone + Polymyxin B on the Kidneys?
Very few cases of side effects of Chloramphenicol + Dexamethasone + Polymyxin B on kidney have been reported.
What is the effect of Chloramphenicol + Dexamethasone + Polymyxin B on the Liver?
Chloramphenicol + Dexamethasone + Polymyxin B does not damage the liver.
What is the effect of Chloramphenicol + Dexamethasone + Polymyxin B on the Heart?
You can take Chloramphenicol + Dexamethasone + Polymyxin B without any fear of damage to the heart.
Chloramphenicol + Dexamethasone + Polymyxin B should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Chloramphenicol + Dexamethasone + Polymyxin B unless your doctor advises you to do so -
Is this Chloramphenicol + Dexamethasone + Polymyxin B habit forming or addictive?
Forming a habit of Chloramphenicol + Dexamethasone + Polymyxin B has not been reported.
Interaction between Food and Chloramphenicol + Dexamethasone + Polymyxin B
Taking Chloramphenicol + Dexamethasone + Polymyxin B with food does not harm your health.
Interaction between Alcohol and Chloramphenicol + Dexamethasone + Polymyxin B
Information about the interaction of Chloramphenicol + Dexamethasone + Polymyxin B and alcohol is not currently available because this topic has not been researched yet.
Yes, Chloramphenicol + Dexamethasone + Polymyxin B can be taken with ibuprofen. No harmful drug interaction has been reported between them. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.
Chloramphenicol + Dexamethasone + Polymyxin B is bacteriostatic at the therapeutic dose that means it inhibits the growth of the bacteria but it can be bactericidal at higher doses. It works by inhibiting the protein synthesis in bacteria which it needs to survive. In the absence of protein synthesis, the bacterial growth is stunned and slowed.
The dosage of Chloramphenicol + Dexamethasone + Polymyxin B may vary from case to case as it depends on the type of infection and severity of the infection. You are recommended to take this drug as per your doctor's instructions. Chloramphenicol + Dexamethasone + Polymyxin B should be taken empty stomach because food may affect absorption of this drug. Precautions must be taken in patients with improper liver or kidney function.
Discontinuing Chloramphenicol + Dexamethasone + Polymyxin B on your own can increase the chances of bacterial resistance and infection relapse. It is recommended that you always consult your doctor if you have decided to discontinue this medicine.
Chloramphenicol + Dexamethasone + Polymyxin B contains chloramphenicol which is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It works by inhibiting the protein synthesis in bacteria which needs to survive. In the absence of protein, the bacterial growth is stunned and slowed. It can also kill the bacteria in higher doses. Chloramphenicol + Dexamethasone + Polymyxin B is effective against a wide range of both gram negative and gram positive bacteria such as Salmonella species, Rickettsia species, Neisseria meningitidis, Escherichia coli, Haemophilus influenzae, and Staphylococcus pneumoniae.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Chloromycetin sodium succinate (chaloramphenicol sodium succinate)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 739-742
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 362-366
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 289
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Decadron® (dexamethasone)
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Hemady™ (dexamethasone)
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Hexadrol® (dexamethasone sodium phosphate)
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Polymyxin B
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 759