Isotret

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  • Manufactured by: Zydus Cadila
  • Contains / Salt: Isotretinoin (20 mg)

Isotret Information

Isotret is a commercial drug that is prescribed in the form of Capsule. Pimples are some of its major therapeutic uses.

The optimal dosage of Isotret is largely dependent on the individual's body weight, medical history, gender and age. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. For detailed information on this, read through the dosage section.

Apart from the aforementioned side effects, Isotret can also lead to other problems, which have been listed below. These side effects of Isotret are usually temporary and subside with the completion of treatment. However, if these continue for a longer time, consult your doctor right away.

In addition, Isotret's effect is Severe during pregnancy and Moderate for lactating mothers. It is important to know if Isotret has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Isotret related warnings section.

Isotret is contraindicated in people with pre-existing medical conditions like Depression as it can result in adverse effects. Other conditions have been mentioned below in the Isotret contraindications section.

Besides this, Isotret may also have severe interaction with some medicines. A complete list of these interactions is given below.

Along with the above-mentioned precautions, remember that taking Isotret is considered safe while driving, and is addictive.


Isotret Benefits & Uses

Isotret is used to treat the following -

Main Benefits

Isotret Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease:
  • Before or After Meal: After Meal
  • Single Maximum Dose: 0.5 mg/kg
  • Dosage Form: Capsule
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 5 months
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease:
  • Before or After Meal: After Meal
  • Single Maximum Dose: 0.5 mg/kg
  • Dosage Form: Capsule
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 5 months
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease:
  • Before or After Meal: After Meal
  • Single Maximum Dose: 0.5 mg/kg
  • Dosage Form: Capsule
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: 5 months
  • Special Instructions: As prescribed by the doctor

Isotret Side Effects

Based on research, the following side effects have been observed when Isotret is used -

Moderate

  • Hypercholesterolaemia
  • Increased Liver Enzymes

Mild

Isotret Related Warnings

  • Is the use of Isotret safe for pregnant women?


    Pregnant women may get severe side effects after taking Isotret. If you are pregnant, do not take Isotret without a doctor's advice.

    Severe
  • Is the use of Isotret safe during breastfeeding?


    Isotret may lead to some side effects in breastfeeding women. If you witness any unusal symptoms after taking Isotret, discontinue its use and call your doctor right away. Follow your doctor's advice regarding the use of Isotret.

    Moderate
  • What is the effect of Isotret on the Kidneys?


    Isotret has very mild side effects on the kidneys.

    Mild
  • What is the effect of Isotret on the Liver?


    There may be an adverse effect on the liver after taking Isotret. If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.

    Moderate
  • What is the effect of Isotret on the Heart?


    The heart can be affected by Isotret. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart the medicine only after medical advice.

    Moderate

Severe Interaction of Isotret with Other Drugs

Isotret should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Isotret Contraindications

If you are suffering from any of the following diseases, you should not take Isotret unless your doctor advises you to do so -


Frequently asked Questions about Isotret

  • Is this Isotret habit forming or addictive?


    Isotret does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Isotret will not make you feel sleepy or drowsy. So you drive or operate machinery safely.

    Safe
  • Is it safe?


    Yes, but take Isotret only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Isotret in mental disorders is not effective.

    No

Isotret Interactions with Food and Alcohol

  • Interaction between Food and Isotret


    Isotret may take longer to act if you eat some foods while taking it. Follow your doctor's advice on this.

    Mild
  • Interaction between Alcohol and Isotret


    Drinking alcohol while taking Isotret may lead to slight side effects. If you experience any side effects, contact your doctor.

    Mild

See all substitutes for Isotret


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
7 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 718-719

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 894-895

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Accutane® (isotretinoin)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Absorica™ (isotretinoin)

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