Paracetamol + Phenylephrine Tablet - Kuffery Plus Tablet

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Paracetamol + Phenylephrine Information

Paracetamol + Phenylephrine is a prescription medicine. Paracetamol + Phenylephrine also has some secondary and off-label uses. These are listed below.

Medical history of the patient along with age and gender determines the dosage of Paracetamol + Phenylephrine. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Refer to the dosage section for a detailed discussion.

While these are the most often observed Paracetamol + Phenylephrine side effects, there are can be others also. These have been listed below. Such side effects of Paracetamol + Phenylephrine normally do not last long and go away once the treatment is completed. If, however, they worsen or do not go away, please speak with your physician.

In addition, Paracetamol + Phenylephrine's effect is Moderate during pregnancy and Mild for lactating mothers. Further, the section on Paracetamol + Phenylephrine related warnings talks about Paracetamol + Phenylephrine's effects on the liver, heart and kidney.

Paracetamol + Phenylephrine can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Paracetamol + Phenylephrine in conditions like Kidney Disease, Liver Disease, Drug Allergies. The section on Paracetamol + Phenylephrine contraindications lists all such conditions.

Besides this, Paracetamol + Phenylephrine may also have severe interaction with some medicines. See below for a complete list.

You should also be aware that Paracetamol + Phenylephrine is not safe while driving, and is not addiction.



Paracetamol + Phenylephrine Benefits & Uses

Paracetamol + Phenylephrine is used to treat the following -

Other Benefits

Paracetamol + Phenylephrine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
13 - 18 years (Adolescent)
  • Disease: Blocked Nose (Nasal Congestion)
  • Before or After Meal: After Meal
  • Single Maximum Dose: 2 Tablet
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 4 hourly
  • Course Duration: 7 days
  • Special Instructions: strength 325 mg paracetamol and 5 mg phenylephrine
Adult
  • Disease: Blocked Nose (Nasal Congestion)
  • Before or After Meal: After Meal
  • Single Maximum Dose: 2 Tablet
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 4 hourly
  • Course Duration: 7 days
  • Special Instructions: strength 325 mg paracetamol and 5 mg phenylephrine
Geriatric
  • Disease: Blocked Nose (Nasal Congestion)
  • Before or After Meal: After Meal
  • Single Maximum Dose: 2 Tablet
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 4 hourly
  • Course Duration: 7 days
  • Special Instructions: strength 325 mg paracetamol and 5 mg phenylephrine


Paracetamol + Phenylephrine Side Effects

Based on research, the following side effects have been observed when Paracetamol + Phenylephrine is used -

Severe

Moderate

Mild

  • Swelling
  • Rash
  • Diarrhoea
  • Injection Site Allergic Reaction
  • Nausea or vomiting
  • Headache
  • Palpitations (fluttering in chest)
  • Restlessness
  • Tremor

Paracetamol + Phenylephrine Related Warnings

  • Is the use of Paracetamol + Phenylephrine safe for pregnant women?


    Paracetamol + Phenylephrine may cause moderate side effects during pregnancy. If you feel its harmful effects, then stop taking this drug immediately, and do not take Paracetamol + Phenylephrine again without your doctor's advice.

  • Is the use of Paracetamol + Phenylephrine safe during breastfeeding?


    Paracetamol + Phenylephrine may have very limited harmful effects for breastfeeding women.

  • What is the effect of Paracetamol + Phenylephrine on the Kidneys?


    Paracetamol + Phenylephrine rarely harms the kidneys.

  • What is the effect of Paracetamol + Phenylephrine on the Liver?


    Paracetamol + Phenylephrine has very mild side effects on the liver.

  • What is the effect of Paracetamol + Phenylephrine on the Heart?


    Paracetamol + Phenylephrine may have mild side effects on the heart. Most people will never see any effect on the heart.



Severe Interaction of Paracetamol + Phenylephrine with Other Drugs

Paracetamol + Phenylephrine should not be taken with following medicines due to severe side effects it may cause to patients -

Life Threatening

Severe

Moderate

Mild



Paracetamol + Phenylephrine Contraindications

If you are suffering from any of the following diseases, you should not take Paracetamol + Phenylephrine unless your doctor advises you to do so -



Frequently asked Questions about Paracetamol + Phenylephrine

  • Is this Paracetamol + Phenylephrine habit forming or addictive?


    No, you will not get addicted to Paracetamol + Phenylephrine.

Paracetamol + Phenylephrine Interactions with Food and Alcohol

  • Interaction between Food and Paracetamol + Phenylephrine


    Taking Paracetamol + Phenylephrine with food does not harm your health.

  • Interaction between Alcohol and Paracetamol + Phenylephrine


    Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Paracetamol + Phenylephrine.



Frequently asked Questions about Paracetamol + Phenylephrine

Question over 4 years ago

What are the interactions between Paracetamol + Phenylephrine and codeine?

Dr. Kuldeep Meena MBBS, MD , Cardiology, Neurology, Pediatrics, Dermatology, Pulmonology, Nephrology, General Physician, Other, Infectious Disease, Emergency Medicine, Allergy and Immunology, Internal Medicine, Multispeciality

No harmful interactions have been reported between Paracetamol + Phenylephrine and codeine. Do not take it until and unless prescribed. However, if you are experiencing any unpleasant medicinal side effects such as nausea, stomach pain, and tremors after taking Paracetamol + Phenylephrine. Inform your doctor immediately.

Question about 5 years ago

What are the uses of Paracetamol + Phenylephrine?

Dr. Haleema Yezdani MBBS , General Physician

Paracetamol + Phenylephrine is primarily used to reduce pain and fever. It can a for other conditions such as a headache, muscle aches, backache, toothaches, and colds.

Question about 5 years ago

Is it safe to use Paracetamol + Phenylephrine in pregnancy?

Paracetamol + Phenylephrine is being used by pregnant women for many years without any evident harmful effects on the baby. That's why it is usually recommended as the first-line painkiller for pregnant women. But it is not possible to say that this medicine is completely safe to use in pregnancy. You are highly recommended to check with your doctor/gynaecologist before taking any medicine even [medicine] during pregnancy.

Question about 5 years ago

Can I use Paracetamol + Phenylephrine in migraine?

Dr. Saurabh Shakya MBBS , General Physician

Yes, you can use Paracetamol + Phenylephrine in a migraine. Paracetamol and other NSAIDs are used in treating migraine. However, there are other medicines available that are better for treating migraine than Paracetamol + Phenylephrine. Please consult a doctor to know about these alternative medicines.

Question about 5 years ago

How does Paracetamol + Phenylephrine work?

Although it's believed that Paracetamol + Phenylephrine works mainly in the central nervous system (Brain and Spine). It prevents the release of prostaglandin, which is responsible for increasing pain and body temperature. It effectively reduces the intensity of pain signals to the brain.



See all substitutes for Paracetamol + Phenylephrine


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

KD Tripathi. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 206-207

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Acetaminophen (acetaminophen)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Ofirmev (acetaminophen)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Vazculep (phenylephrine hydrochloride)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 135-136

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1020-1022

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