Paroxetine

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  • Manufactured by: Jan Aushadhi
  • Contains / Salt: Paroxetine
  • Storage: translation missing: en.0

Paroxetine Information

Paroxetine is a prescription medicine. It is primarily used for the treatment of Depression. Paroxetine also has some secondary and off-label uses. These are listed below.

The correct dosage of Paroxetine depends on the patient's age, gender, and medical history. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. This information has been provided in detail in the dosage section.

Besides the aforementioned side effects, there are other adverse effects of Paroxetine as well, which are listed below. These side effects of Paroxetine are usually temporary and subside with the completion of treatment. However, if these continue for a longer time, consult your doctor right away.

Paroxetine's effect during pregnancy is Severe and Severe while nursing. In addition, Paroxetine's effects on the liver, heart and kidney are discussed below in the Paroxetine related warnings section.

Paroxetine is contraindicated in people with pre-existing medical conditions like Depression as it can result in adverse effects. Other contraindications of Paroxetine have been discussed in the sections ahead.

Drug interactions for Paroxetine have been reported in the medical literature. A complete list of these interactions is given below.

In addition to the above precautions for Paroxetine, it is important to know that it is not safe while driving, and is not habit-forming.


Paroxetine Benefits & Uses

Paroxetine is used to treat the following -

Main Benefits

Other Benefits

Paroxetine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Depression
  • Before or After Meal: After Meal
  • Single Maximum Dose: 20 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: dosage range: 20 - 40 mg/day
Geriatric
  • Disease: Depression
  • Before or After Meal: After Meal
  • Single Maximum Dose: 10 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage range: 10 - 40 mg/day

Paroxetine Side Effects

Based on research, the following side effects have been observed when Paroxetine is used -

Moderate

Mild

Paroxetine Related Warnings

  • Is the use of Paroxetine safe for pregnant women?


    Paroxetine has many dangerous side effects in pregnant women. If you are pregnant, do not consume Paroxetine without medical advice.

    Severe
  • Is the use of Paroxetine safe during breastfeeding?


    Women who are breastfeeding, may experience serious side effects after taking Paroxetine. So it is adviced to consult the doctor before using it.

    Severe
  • What is the effect of Paroxetine on the Kidneys?


    Paroxetine rarely affects the kidneys.

    Mild
  • What is the effect of Paroxetine on the Liver?


    Paroxetine is rarely harmful for the liver.

    Mild
  • What is the effect of Paroxetine on the Heart?


    Paroxetine is rarely harmful for the heart.

    Mild

Severe Interaction of Paroxetine with Other Drugs

Paroxetine should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Paracetamol,Chlorpheniramine,Dextromethorphan
    Paracetamol,Tramadol
      Dextromethorphan

      Moderate

      Mild


      Paroxetine Contraindications

      If you are suffering from any of the following diseases, you should not take Paroxetine unless your doctor advises you to do so -


      Frequently asked Questions about Paroxetine

      • Is this Paroxetine habit forming or addictive?


        Paroxetine does not cause addiction.

        No
      • Is it safe to drive or operate heavy machinery when consuming?


        After taking Paroxetine, you should not drive or work on any heavy machine, as Paroxetine can make you drowsy.

        Dangerous
      • Is it safe?


        Paroxetine is safe but it is important to consult a doctor before taking it.

        Safe, but take only on Doctor's advise
      • Is it able to treat mental disorders?


        Yes, Paroxetine is useful in treating mental disorders.

        Yes

      Paroxetine Interactions with Food and Alcohol

      • Interaction between Food and Paroxetine


        Taking Paroxetine with food does not harm your health.

        Safe
      • Interaction between Alcohol and Paroxetine


        Consumption of alcohol and Paroxetine together may have severe effects on your health.

        Severe

      Frequently asked Questions about Paroxetine

      Question over 4 years ago

      Is Paroxetine an anti-psychotic drug?

      Dr. Kapil Sharma MBBS , General Physician

      No, Paroxetine is not an antipsychotic drug. It contains paroxetine which belongs to the class of drugs known as selective serotonin reuptake inhibitors (SSRIs). It is used for the treatment of depression (major depressive disorder) and anxiety (generalized anxiety disorder). Paroxetine is also used in the treatment of obsessive-compulsive disorder (OCD) and panic disorder with or without agoraphobia.

      Question over 4 years ago

      Is Paroxetine addictive?

      Dr. Kapil Sharma MBBS , General Physician

      No, Paroxetine is not addictive. It has not been reported to cause addiction among those who are taking this drug.

      Question over 4 years ago

      Can Paroxetine cause suicidal and self-inflicting thoughts?

      Dr. Kapil Sharma MBBS , General Physician

      Patients who are suffering from major depressive disorder may experience a change in suicidal behavior, and self-inflicting thought whether they are taking Paroxetine or not and this risk may remain till significant remission of depression. If you are experiencing mood fluctuations, life-threatening, distorted thoughts after taking this drug, consult your doctor immediately without any further delay.

      Question almost 5 years ago

      Does Paroxetine cause weight fluctuation?

      Dr. Rahul Poddar MBBS, DNB, MBBS, DNB , General Surgery

      Yes, Paroxetine has been reported to cause weight fluctuation (weight gain or loss). It is a known side effect of this drug. However, if you experience any unusual sudden weight gain or loss after taking this drug, then consult it with your doctor without further delay.

      Question about 4 years ago

      Can I take Paroxetine and amitriptyline together?

      Dr. Gaurav MBBS , General Physician

      No, Paroxetine and amitriptyline cannot be taken together. Because this combination may increase serious side effects such as dry mouth, sedation, blurred vision, and urine retention. Before taking these two medicines together you must consult your doctor.


      See all substitutes for Paroxetine


      This medicine data has been created by -

      Vikas Chauhan
      B.Pharma, Pharmacy
      5 Years of Experience

      References

      April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 986-988

      KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 461

      US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Paxil® (paroxetine hydrochloride)

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