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Pyrin is a prescription medicine that is available as a Tablet. Fever, Headache, Pain are some of its major therapeutic uses. Pyrin also has some secondary and off-label uses. These are listed below.
The optimal dosage of Pyrin is largely dependent on the individual's body weight, medical history, gender and age. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Detailed information has been provided in the dosage section.
Apart from the aforementioned side effects, Pyrin can also lead to other problems, which have been listed below. Such side effects of Pyrin normally do not last long and go away once the treatment is completed. Please speak with your doctor if these side effects worsen or persist for a longer duration.
In addition, Pyrin's effect is Safe during pregnancy and Safe for lactating mothers. It is important to know if Pyrin has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Pyrin related warnings section.
Pyrin is not recommended if you suffer from certain medical conditions as it can have adverse effects. Kidney Disease, Liver Disease, Drug Allergies are examples of such conditions. The section on Pyrin contraindications lists all such conditions.
Besides this, Pyrin may also have severe interaction with some medicines. Refer to the list below for further details.
In addition to the above precautions for Pyrin, it is important to know that it is safe while driving, and is habit-forming.
Pyrin is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
2 - 12 years (Child) |
|
13 - 18 years (Adolescent) |
|
Is the use of Pyrin safe for pregnant women?
Pyrin is safe for pregnant women.
Is the use of Pyrin safe during breastfeeding?
Pyrin is safe for breastfeeding women.
What is the effect of Pyrin on the Kidneys?
Pyrin has very mild side effects on the kidneys.
What is the effect of Pyrin on the Liver?
You may experience side effects on your liver after taking Pyrin. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.
What is the effect of Pyrin on the Heart?
Side effects of Pyrin rarely affect the heart.
Pyrin should not be taken with following medicines due to severe side effects it may cause to patients -
Life Threatening
Severe
Moderate
Mild
If you are suffering from any of the following diseases, you should not take Pyrin unless your doctor advises you to do so -
Is this Pyrin habit forming or addictive?
No, you will not get addicted to Pyrin.
Is it safe to drive or operate heavy machinery when consuming?
Yes, you can operate a vehicle or heavy machinery after taking Pyrin since it does not cause drowsiness.
Is it safe?
Yes, but consume Pyrin only on doctor's advice.
Is it able to treat mental disorders?
No, Pyrin cannot treat any kind of mental disorder.
Interaction between Food and Pyrin
Due to a lack of research, nothing can be said about the consequences of taking Pyrin together with food.
Interaction between Alcohol and Pyrin
Taking Pyrin with alcohol can have severely harmful effects on your health.
Pyrin is not recommended for back pain. However, It can be taken along with a painkiller for the treatment of back pain.
An overdose occurs when more than the required amount (toxic levels) of [medicine] is taken. Initial symptoms of Pyrin overdose includes loss of appetite, drowsiness, seizures, abdominal pain, nausea, and vomiting. Later progressive symptoms may include pain in your upper stomach, dark colored urine, yellowing of your skin or the white patches in your eyes, liver damage and in rare cases, it can also lead to coma. So, by any chance, if you have accidentally taken more than the required dose of Pyrin inform your doctor immediately.
Although it's believed that Pyrin works mainly in the central nervous system (Brain and Spine). It prevents the release of prostaglandin, which is responsible for increasing pain and body temperature. It effectively reduces the intensity of pain signals to the brain.
As we know Pyrin is most widely used 'over-the-counter' analgesic/antipyretic medicine. However, paracetamol overdose can cause serious adverse effects on the liver, it may be fatal. But fortunately, there is an antidote, N-acetylcysteine (NAC) given within 8 hours of Pyrin ingestion which usually can prevent all serious side effects of Pyrin poisoning. However, do not take NAC without consulting a doctor as your doctor will tell you the right way and methods to help you relieve from this drug poisoning.
Yes, you can use Pyrin in a migraine. Paracetamol and other NSAIDs are used in treating migraine. However, there are other medicines available that are better for treating migraine than Pyrin. Please consult a doctor to know about these alternative medicines.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
KD Tripathi. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 206-207
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Acetaminophen (acetaminophen)
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Ofirmev (acetaminophen)