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Zolpidem Information

Zolpidem is a prescription medicine. It is primarily used for the treatment of Insomnia.

The optimal dosage of Zolpidem is largely dependent on the individual's body weight, medical history, gender and age. Individual symptoms and route of administration also determines the right dosage. Refer to the dosage section for a detailed discussion.

Besides the aforementioned side effects, there are other adverse effects of Zolpidem as well, which are listed below. Such side effects of Zolpidem normally do not last long and go away once the treatment is completed. However, if these continue for a longer time, consult your doctor right away.

It is also important to note that Zolpidem has a Moderate effect for pregnant women and Moderate effect on lactating mothers. Warnings related to Zolpidem's effects on the liver, heart and kidney, if any, have been listed below.

Zolpidem is not recommended if you suffer from certain medical conditions as it can have adverse effects. Depression, Angioedema are examples of such conditions. Other conditions have been mentioned below in the Zolpidem contraindications section.

Drug interactions for Zolpidem have been reported in the medical literature. See below for a complete list.

Along with the above-mentioned precautions, remember that taking Zolpidem is considered not safe while driving, and is not addictive.

  1. Zolpidem Benefits & Uses
  2. Zolpidem Dosage & How to Take
  3. Zolpidem Side Effects
  4. Zolpidem Related Warnings
  5. Severe Interaction of Zolpidem with Other Drugs
  6. Zolpidem Contraindications
  7. Frequently asked Questions about Zolpidem
  8. Zolpidem Interactions with Food and Alcohol

Zolpidem Benefits & Uses

Zolpidem is used to treat the following -

  1. Insomnia Primary

Zolpidem Dosage & How to Take

Find the right dosage based on disease and age

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Ingredients of Zolpidem


Zolpidem Side Effects

Based on research, the following side effects have been observed when Zolpidem is used -

  1. Fainting
  2. Uncoordinated Body Movements
  3. Memory problems
  4. Anxiety Mild
  5. Headache Mild
  6. Hallucinations
  7. Agitation
  8. Diarrhoea
  9. Nausea or vomiting
  10. Dizziness Mild
  11. Dry Mouth Mild
  12. Depression Moderate
  13. Drowsiness
  14. Back Pain Mild
  15. Fatigue Mild
  16. Low energy

Zolpidem Related Warnings

Is the use of Zolpidem safe for pregnant women?

Pregnant women may experience moderate side effects from Zolpidem. It is best to stop taking Zolpidem immediately and inform your doctor if you notice any discomfort.


Is the use of Zolpidem safe during breastfeeding?

Zolpidem may lead to some side effects in breastfeeding women. If you witness any unusal symptoms after taking Zolpidem, discontinue its use and call your doctor right away. Follow your doctor's advice regarding the use of Zolpidem.


What is the effect of Zolpidem on the Kidneys?

Using Zolpidem does not have any harmful effects on kidneys.


What is the effect of Zolpidem on the Liver?

Very few cases of side effects of Zolpidem on the liver have been reported.


What is the effect of Zolpidem on the Heart?

Using Zolpidem does not have any harmful effects on the heart.


Severe Interaction of Zolpidem with Other Drugs

Zolpidem should not be taken with following medicines due to severe side effects it may cause to patients -




    Zolpidem Contraindications

    If you are suffering from any of the following diseases, you should not take Zolpidem unless your doctor advises you to do so -

    1. Depression
    2. Angioedema
    3. Suicidal Tendency
    4. COPD (Chronic Obstructive Pulmonary Disease)

    Frequently asked Questions about Zolpidem

    Is this Zolpidem habit forming or addictive?

    Yes, Zolpidem can get addictive. Consume it only after doctor's advise.


    Is it safe to drive or operate heavy machinery when consuming?

    After taking Zolpidem, you should not drive or work on any heavy machine, as Zolpidem can make you drowsy.


    Is it safe?

    Zolpidem should be used only after doctor's advice.

    Safe, but take only on Doctor's advise

    Is it able to treat mental disorders?

    Yes, Zolpidem is useful in treating mental disorders.


    Zolpidem Interactions with Food and Alcohol

    Interaction between Food and Zolpidem

    Taking Zolpidem with food does not cause any problems.


    Interaction between Alcohol and Zolpidem

    Consumption of alcohol and Zolpidem together may have severe effects on your health.


    Zolpidem FAQs

    Question almost 2 years ago

    Does Zolpidem cause weight loss?

    Dr. Keshu Lal Damor MBBS , General Physician, Other, Obstetrics & Gynaecology

    No, Zolpidem does not cause weight changes (weight gain or loss). It has not been reported by the patients who are taking this drug. However, if you are experiencing any unusual weight changes then it might be due to some medical condition and you are advised to discuss it with your doctor.

    Question about 2 years ago

    How to take Zolpidem?

    Dr. Joydeep Sarkar MBBS , General Physician

    Take one tablet of Zolpidem at bedtime or as advised by your doctor. Ideally, oral Zolpidem should be taken empty stomach because the presence of food might affect the absorption of this drug from the stomach. Precautions must be taken in patients with obstructive sleep apnoea, myasthenia gravis, and compromised respiratory function.

    Question 11 months ago

    Can I take Zolpidem with Benadryl?

    Dr. Yogesh Kumar MBBS , General Physician

    Yes Zolpidem can be taken with Benadryl (diphenhydramine). Benadryl does not appear to interfere with the efficacy of Zolpidem. Hence, it is alright to take them together. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.

    Question about 1 year ago

    Is Zolpidem a benzodiazepine?

    Dr. Keshu Lal Damor MBBS , General Physician, Other, Obstetrics & Gynaecology

    No, Zolpidem is not a benzodiazepine. It is a nonbenzodiazepine drug that belongs to the class of drug known as imidazopyridine which produces sedative effects similar to the benzodiazepines.

    Question almost 2 years ago

    How long can I safely take Zolpidem?

    Dr. Kapil Sharma MBBS , General Physician

    Ideally, Zolpidem is given for the short-term management of insomnia. You are advised take it as per your doctor's advice. Do not take it longer than prescribed by your doctor to avoid unpleasant side effects.

    This medicine data has been created by -
    Vikas Chauhan
    B.Pharma, Pharmacy
    3 Years of Experience


    1. US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Ambien® (zolpidem tartrate)
    2. KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 406-407
    3. April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1296-1298
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